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Medicine
Germany
2026

D-Index & Metrics

Medicine

D-Index
146
Citations
137520
World Ranking
1311
National Ranking
63

Research.com Recognitions

  • 2026 - Research.com Medicine in Germany Leader Award
  • 2023 - Research.com Medicine in Germany Leader Award

Overview

Werner Hacke is affiliated with Heidelberg University in Germany and has a significant research presence in the field of Medicine, with a primary focus on stroke and cerebrovascular diseases. Their work encompasses a broad spectrum of topics related to acute ischemic stroke management, stroke rehabilitation and recovery, and cerebrovascular and carotid artery diseases.

The main topics covered in their publications include:

  • Acute Ischemic Stroke Management
  • Stroke Rehabilitation and Recovery
  • Cerebrovascular and Carotid Artery Diseases
  • Venous Thromboembolism Diagnosis and Management
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Cardiovascular Health and Disease Prevention

Their research spans several subfields such as Epidemiology, Neurology, Rehabilitation, Pulmonary and Respiratory Medicine, and Internal Medicine.

Werner Hacke has published extensively in peer-reviewed journals. Some of their recent papers include:

  • World Stroke Organization (WSO): Global Stroke Fact Sheet 2022, published in International Journal of Stroke (2022)
  • Challenging the Ischemic Core Concept in Acute Ischemic Stroke Imaging, published in Stroke (2020)
  • Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data, published in The Lancet (2020)
  • Carotid endarterectomy or stenting or best medical treatment alone for moderate-to-severe asymptomatic carotid artery stenosis: 5-year results of a multicentre, randomised controlled trial, published in The Lancet Neurology (2022)
  • Surgical Decompression for Space-Occupying Hemispheric Infarction, published in JAMA Neurology (2020)

Werner Hacke frequently collaborates with other researchers in brain and stroke research. Notable coauthors include:

  • Stephen M. Davis
  • Geoffrey A. Donnan
  • Götz Thomalla
  • Jens Fiehler
  • Steven Warach

Key journals where Werner Hacke has published multiple articles include:

  • Stroke
  • Neurological Research and Practice
  • European Stroke Journal
  • International Journal of Stroke
  • The Lancet

The body of research contributed by Werner Hacke centers on acute interventions for stroke patients, diagnostic approaches including imaging techniques, and longer-term stroke recovery and rehabilitation. The involvement in studies on carotid artery stenosis and surgical treatments for hemispheric infarction illustrates an interest in both clinical and interventional neuroscience.

Best Publications

  • Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation

    Manesh R. Patel;Kenneth W. Mahaffey;Jyotsna Garg;Guohua Pan

  • Thrombolysis with Alteplase 3 to 4.5 Hours After Acute Ischemic Stroke

    Werner Hacke;Markku Kaste;Erich Bluhmki;Miroslav Brozman

  • Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke

    Jeffrey L. Saver;Mayank Goyal;Alain Bonafe;Hans Christoph Diener

  • Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II)

    Werner Hacke;Markku Kaste;Cesare Fieschi;Rüdiger von Kummer

  • Intravenous Thrombolysis With Recombinant Tissue Plasminogen Activator for Acute Hemispheric Stroke: The European Cooperative Acute Stroke Study (ECASS)

    Hacke W;Kaste M;Fieschi C;Toni D

  • Clopidogrel and Aspirin versus Aspirin Alone for the Prevention of Atherothrombotic Events

    Deepak L. Bhatt;Keith A.A. Fox;Werner Hacke;Peter B. Berger

  • Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials

    Werner Hacke;Geoffrey Donnan;Cesare Fieschi;Markku Kaste

  • Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials

    Jonathan Emberson;Kennedy R Lees;Patrick Lyden;Lisa Blackwell

  • Guidelines for management of ischaemic stroke and transient ischaemic attack 2008

    Peter A. Ringleb;Marie Germaine Bousser;Gary Ford;Philip Bath

  • Point-of-Care International Normalized Ratio Testing Accelerates Thrombolysis in Patients With Acute Ischemic Stroke Using Oral Anticoagulants

    Timolaos Rizos;Christian Herweh;Ekkehart Jenetzky;Christoph Lichy

  • Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study

    Nils Wahlgren;Niaz Ahmed;Antoni Dávalos;Gary A Ford

  • Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials.

    Kennedy R Lees;Erich Bluhmki;Rüdiger von Kummer;Thomas G Brott

  • 30 day results from the SPACE trial of stent-protected angioplasty versus carotid endarterectomy in symptomatic patients: a randomised non-inferiority trial.

    Ringleb Pa;Allenberg J;Brückmann H

  • Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials

    Katayoun Vahedi;Jeannette Hofmeijer;Eric Juettler;Eric Vicaut

  • 'Malignant' Middle Cerebral Artery Territory Infarction: Clinical Course and Prognostic Signs

    Hacke W;Schwab S;Horn M;Spranger M

  • Carotid artery stenting compared with endarterectomy in patients with symptomatic carotid stenosis (International Carotid Stenting Study): an interim analysis of a randomised controlled trial

    Jörg Ederle;Joanna Dobson;Joanna Dobson;Roland L. Featherstone;Leo H. Bonati;Leo H. Bonati

  • Recommendations on Angiographic Revascularization Grading Standards for Acute Ischemic Stroke A Consensus Statement

    Osama O. Zaidat;Albert J. Yoo;Pooja Khatri;Thomas A. Tomsick

  • Updated European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist anticoagulants in patients with non-valvular atrial fibrillation.

    Hein Heidbuchel;Peter Verhamme;Marco Alings;Matthias Antz

  • Risk Factors, Outcome, and Treatment in Subtypes of Ischemic Stroke The German Stroke Data Bank

    Armin J. Grau;Christian Weimar;Florian Buggle;Alexander Heinrich

  • The Desmoteplase in Acute Ischemic Stroke Trial (DIAS): A Phase II MRI-Based 9-Hour Window Acute Stroke Thrombolysis Trial With Intravenous Desmoteplase

    Werner Hacke;Greg Albers;Yasir Al-Rawi;Julien Bogousslavsky

Frequent Co-Authors

Peter A. Ringleb
Peter A. Ringleb University Hospital Heidelberg
Stefan Schwab
Stefan Schwab University of Erlangen-Nuremberg
Keith A.A. Fox
Keith A.A. Fox University of Edinburgh
Graeme J. Hankey
Graeme J. Hankey University of Western Australia
Peter D. Schellinger
Peter D. Schellinger Ruhr University Bochum
Markku Kaste
Markku Kaste University of Helsinki
Manesh R. Patel
Manesh R. Patel Duke University
Kennedy R. Lees
Kennedy R. Lees University of Glasgow
Kenneth W. Mahaffey
Kenneth W. Mahaffey Stanford University
Richard C. Becker
Richard C. Becker University of Cincinnati

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