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Medicine

D-Index
79
Citations
23225
World Ranking
17547
National Ranking
8778

Overview

Lewis B. Holmes is a researcher primarily affiliated with Harvard University in the United States with a focus in the field of Medicine. Their work spans several subfields including Pediatrics, Perinatology and Child Health, Public Health, Environmental and Occupational Health, Psychiatry and Mental Health, Surgery, and Infectious Diseases.

The scientist's research covers multiple main topics, with notable attention to pharmacological effects and toxicity studies, pregnancy and medication impact, epilepsy research and treatment, prenatal screening and diagnostics, congenital limb and hand anomalies, assisted reproductive technology and twin pregnancy, and congenital anomalies and fetal surgery.

Holmes has published extensively in various academic venues. Frequent publication outlets include:

  • Birth Defects Research
  • American Journal of Medical Genetics Part A
  • UNC Libraries
  • The Lancet
  • Clinical Infectious Diseases

Recent papers from Holmes and collaborators illustrate their diverse research interests. These include:

  • "Limited surface examination to evaluate potential teratogens in a resource-limited setting" (2021, Birth Defects Research)
  • "Efficacy and safety of dolutegravir with emtricitabine and tenofovir alafenamide fumarate or tenofovir disoproxil fumarate, and efavirenz, emtricitabine, and tenofovir disoproxil fumarate HIV antiretroviral therapy regimens started in pregnancy (IMPAACT 2010/VESTED): a multicentre, open-label, randomised, controlled, phase 3 trial" (2021, The Lancet)
  • "Global birth defects app: An innovative tool for describing and coding congenital anomalies at birth in low resource settings" (2021, Birth Defects Research)
  • "Weight Changes and Adverse Pregnancy Outcomes With Dolutegravir- and Tenofovir Alafenamide Fumarate-Containing Antiretroviral Treatment Regimens During Pregnancy and Postpartum" (2024, Clinical Infectious Diseases)
  • "Neuropsychological effects in children exposed to anticonvulsant monotherapy during gestation: Phenobarbital, carbamazepine, and phenytoin" (2022, Epilepsy & Behavior)

Collaboration forms a key part of Holmes's research practice. Frequent coauthors include:

  • Roger Shapiro
  • Hanah Nasri
  • Anne-Therese Hunt
  • Kevin Knowles
  • William Murtaugh

Best Publications

  • The Teratogenicity of Anticonvulsant Drugs

    Lewis B. Holmes;Elizabeth A. Harvey;Brent A. Coull;Kelly B. Huntington

  • Comparative safety of antiepileptic drugs during pregnancy

    S. Hernández-Díaz;C.R. Smith;A. Shen;R. Mittendorf

  • Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome

    M Bamshad;R C Lin;D J Law;W C Watkins

  • Guidelines for case classification for the National Birth Defects Prevention Study.

    Sonja A Rasmussen;Richard S Olney;Lewis B Holmes;Angela E Lin

  • Practice parameter update: management issues for women with epilepsy - focus on pregnancy (an evidence-based review): teratogenesis and perinatal outcomes. Report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society

    C. L. Harden;K. J. Meador;P. B. Pennell;W. A. Hauser

  • Increased rate of major malformations in offspring exposed to valproate during pregnancy

    D. F. Wyszynski;M. Nambisan;T. Surve;R. M. Alsdorf

  • Antidepressant Use in Pregnancy and the Risk of Cardiac Defects

    K.F. Huybrechts;K. Palmsten;J. Avorn;L.S. Cohen

  • Metabolic Control and Progression of Retinopathy: The Diabetes in Early Pregnancy Study

    Emily Y. Chew;James L. Mills;Boyd E Metzger;Nancy A. Remaley

  • Neural-Tube Defects and Antiretroviral Treatment Regimens in Botswana

    Rebecca Zash;Lewis Holmes;Modiegi Diseko;Denise L. Jacobson

  • Practice Parameter update: Management issues for women with epilepsy—Focus on pregnancy (an evidence-based review): Vitamin K, folic acid, blood levels, and breastfeeding: Report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society

    C. L. Harden;P. B. Pennell;B. S. Koppel;C. A. Hovinga

  • Malformations due to presumed spontaneous mutations in newborn infants.

    Kathryn Nelson;Lewis B. Holmes

  • Congenital abnormalities in Brazilian children associated with misoprostol misuse in first trimester of pregnancy

    Claudette Hajaj Gonzalez;Maria Joaquina Marques-Dias;Chong Ae Kim;Sofia M M Sugayama

  • Practice Parameter update: Management issues for women with epilepsy—Focus on pregnancy (an evidence-based review): Obstetrical complications and change in seizure frequency Report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society

    C. L. Harden;J. Hopp;T. Y. Ting;P. B. Pennell

  • Etiologic heterogeneity of neural-tube defects.

    Lewis B. Holmes;Shirley G. Driscoll;Leonard Atkins

  • INCREASED FREQUENCY OF ISOLATED CLEFT PALATE IN INFANTS EXPOSED TO LAMOTRIGINE DURING PREGNANCY

    L. B. Holmes;E. J. Baldwin;C. R. Smith;E. Habecker

  • Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review): II. Teratogenesis and perinatal outcomes: Report of the Quality Standards Subcommittee and Therapeutics and Technology Subcommittee of the American Academy of Neurology and the American Epilepsy Society.

    Cynthia L. Harden;Cynthia L. Harden;Kimford J. Meador;Page B. Pennell;W. Allen Hauser

  • Molecular and Clinical Analyses of Greig Cephalopolysyndactyly and Pallister-Hall Syndromes: Robust Phenotype Prediction from the Type and Position of GLI3 Mutations

    Jennifer J. Johnston;Isabelle Olivos-Glander;Christina Killoran;Emma Elson

  • Predictive value of minor anomalies. I. Association with major malformations

    Kathleen A. Leppig;Kathleen A. Leppig;Martha M. Werler;Martha M. Werler;Cristina I. Cann;Cristina I. Cann;Catherine A. Cook;Catherine A. Cook

  • The AED (antiepileptic drug) pregnancy registry: a 6-year experience.

    Lewis B. Holmes;Diego F. Wyszynski;Ellice Lieberman

  • Novel HOXA13 Mutations and the Phenotypic Spectrum of Hand-Foot-Genital Syndrome

    Frances R. Goodman;Chiara Bacchelli;Angela F. Brady;Louise A. Brueton

Frequent Co-Authors

James L. Mills
James L. Mills National Institutes of Health
Sonia Hernandez-Diaz
Sonia Hernandez-Diaz Harvard University
Boyd E. Metzger
Boyd E. Metzger Northwestern University
Brent A. Coull
Brent A. Coull Harvard University
Page B. Pennell
Page B. Pennell University of Pittsburgh
Jacqueline A. French
Jacqueline A. French New York University
Hershel Jick
Hershel Jick Boston University
Ellice Lieberman
Ellice Lieberman Brigham and Women's Hospital
Richard H. Finnell
Richard H. Finnell Baylor College of Medicine
Beryl R. Benacerraf
Beryl R. Benacerraf Harvard University

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