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Immunology

D-Index
46
Citations
9859
World Ranking
4594
National Ranking
2072

Overview

Niki M. Moutsopoulos is affiliated with the National Institutes of Health in the United States. Their research primarily spans medicine, immunology and microbiology, and biochemistry, genetics, and molecular biology. They have a substantial focus on immunology, periodontics, molecular biology, genetics, and epidemiology within these fields.

The scientist's work addresses key areas including oral microbiology and periodontitis research, immune response and inflammation, neutrophil, myeloperoxidase and oxidative mechanisms, oral health pathology and treatment, gut microbiota and health, salivary gland disorders and functions, as well as immunodeficiency and autoimmune disorders.

Recent papers authored or co-authored by Niki M. Moutsopoulos include:

  • "Human oral mucosa cell atlas reveals a stromal-neutrophil axis regulating tissue immunity" (2021, Cell)
  • "Regulation of host-microbe interactions at oral mucosal barriers by type 17 immunity" (2020, Science Immunology)
  • "Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier" (2021, Science)
  • "Aberrant type 1 immunity drives susceptibility to mucosal fungal infections" (2021, Science)
  • "Neutrophil extracellular traps and extracellular histones potentiate IL-17 inflammation in periodontitis" (2023, The Journal of Experimental Medicine)

Frequent co-authors in their publications include Teresa Greenwell-Wild, D. Williams, Lakmali M. Silva, Nicolás Dutzan, and T Ikeuchi. These collaborations contribute to the breadth of their research output.

Their work has been published in venues noteworthy for scientific research, including Science, Immunity, Journal of Dental Research, Cell, and bioRxiv (Cold Spring Harbor Laboratory).

Best Publications

  • Aggregatibacter actinomycetemcomitans–induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis

    Maximilian F. Konig;Loreto Abusleme;Jesper Reinholdt;Robert J. Palmer

  • Human oral mucosa cell atlas reveals a stromal-neutrophil axis regulating tissue immunity.

    Drake Winslow Williams;Teresa Greenwell-Wild;Laurie Brenchley;Nicolas Dutzan;Nicolas Dutzan

  • Low-grade inflammation in chronic infectious diseases: paradigm of periodontal infections.

    Niki M. Moutsopoulos;Phoebus N. Madianos

  • Tissue-Specific Immunity at the Oral Mucosal Barrier

    Niki M. Moutsopoulos;Joanne E. Konkel

  • Systemic and Local Interleukin-17 and Linked Cytokines Associated with Sjögren’s Syndrome Immunopathogenesis

    Gikas E. Katsifis;Sofia Rekka;Niki M. Moutsopoulos;Stanley Pillemer

  • TGF‐β: a mobile purveyor of immune privilege

    Sharon M. Wahl;Jie Wen;Niki Moutsopoulos

  • A dysbiotic microbiome triggers T H 17 cells to mediate oral mucosal immunopathology in mice and humans.

    Nicolas Dutzan;Nicolas Dutzan;Tetsuhiro Kajikawa;Loreto Abusleme;Loreto Abusleme;Teresa Greenwell-Wild

  • Defective Neutrophil Recruitment in Leukocyte Adhesion Deficiency Type I Disease Causes Local IL-17-driven Inflammatory Bone Loss

    Niki M. Moutsopoulos;Joanne Konkel;Mojgan Sarmadi;Mehmet A. Eskan

  • Tumor necrosis factor‐alpha (TNF‐α) is a therapeutic target for impaired cutaneous wound healing

    Gillian S. Ashcroft;Moon Jin Jeong;Moon Jin Jeong;Jason J. Ashworth;Matthew Hardman

  • Redefined clinical features and diagnostic criteria in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy

    Elise M.N. Ferre;Stacey R. Rose;Sergio D. Rosenzweig;Peter D. Burbelo

  • Characterization of the human immune cell network at the gingival barrier

    Nicolas Dutzan;Joanne E Konkel;Teresa Greenwell-Wild;Niki M Moutsopoulos

  • DEL-1 promotes macrophage efferocytosis and clearance of inflammation

    Ioannis Kourtzelis;Ioannis Kourtzelis;Xiaofei Li;Ioannis Mitroulis;Ioannis Mitroulis;Daniel Grosser

  • On-going Mechanical Damage from Mastication Drives Homeostatic Th17 Cell Responses at the Oral Barrier.

    Nicolas Dutzan;Loreto Abusleme;Hayley Bridgeman;Teresa Greenwell-Wild

  • Wound healing: immunological aspects.

    Afrodite K. Tsirogianni;Niki Maria Moutsopoulos;Haralampos M. Moutsopoulos

  • Porphyromonas gingivalis promotes Th17 inducing pathways in chronic periodontitis

    Niki M. Moutsopoulos;Heather M. Kling;Nikola Angelov;Wenwen Jin

  • Regulation of host-microbe interactions at oral mucosal barriers by type 17 immunity

    Sarah L. Gaffen;Niki M. Moutsopoulos

  • Foxp3+ T-Regulatory Cells in Sjögren's Syndrome: Correlation with the Grade of the Autoimmune Lesion and Certain Adverse Prognostic Factors

    Maria I. Christodoulou;Efstathia K. Kapsogeorgou;Niki M. Moutsopoulos;Haralampos M. Moutsopoulos

  • Augmented Interferon-α Pathway Activation in Patients With Sjögren's Syndrome Treated With Etanercept

    Clio P. Mavragani;Timothy B. Niewold;Niki M. Moutsopoulos;Stanley R. Pillemer

  • Oral manifestations of systemic autoimmune and inflammatory diseases: diagnosis and clinical management.

    Jacqueline W. Mays;Mojgan Sarmadi;Niki M. Moutsopoulos

  • Interleukin-12 and Interleukin-23 Blockade in Leukocyte Adhesion Deficiency Type 1.

    Niki M. Moutsopoulos;Christa S. Zerbe;Teresa Wild;Nicolas Dutzan

  • The management of Sjögren's syndrome.

    Clio P Mavragani;Niki M Moutsopoulos;Haralampos M Moutsopoulos

Frequent Co-Authors

Sharon M. Wahl
Sharon M. Wahl National Institutes of Health
George Hajishengallis
George Hajishengallis University of Pennsylvania
Michail S. Lionakis
Michail S. Lionakis National Institute of Allergy and Infectious Diseases
Haralampos M. Moutsopoulos
Haralampos M. Moutsopoulos National and Kapodistrian University of Athens
Steven M. Holland
Steven M. Holland National Institute of Allergy and Infectious Diseases
Alfredo A. Molinolo
Alfredo A. Molinolo University of California, San Diego
Maria I. Morasso
Maria I. Morasso National Institutes of Health
Alexandra F. Freeman
Alexandra F. Freeman National Institute of Allergy and Infectious Diseases
Peter J. Munson
Peter J. Munson Center for Information Technology

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