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Immunology

D-Index
59
Citations
21836
World Ranking
3377
National Ranking
232

Overview

Manfred B. Lutz is affiliated with the University of Würzburg in Germany and conducts research primarily within the fields of Immunology and Microbiology as well as Medicine. Their academic work spans several subfields, notably Immunology, Neurology, Oncology, Cell Biology, and Cellular and Molecular Neuroscience.

The scientist's main research topics include:

  • Immune cells in cancer
  • Immune Response and Inflammation
  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • Inflammation biomarkers and pathways
  • Parkinson's Disease Mechanisms and Treatments

Among recent publications featuring Manfred B. Lutz's contributions are:

  • Neurodegeneration by α-synuclein-specific T cells in AAV-A53T-α-synuclein Parkinson's disease mice (2022, Brain Behavior and Immunity)
  • IL-12 from endogenous cDC1, and not vaccine DC, is required for Th1 induction (2020, JCI Insight)
  • Therapies for tuberculosis and AIDS: myeloid-derived suppressor cells in focus (2020, Journal of Clinical Investigation)
  • Guidelines for mouse and human DC generation (2022, European Journal of Immunology)
  • Transient regulatory T-cell targeting triggers immune control of multiple myeloma and prevents disease progression (2021, Leukemia)

The venues most frequently publishing their work include:

  • Frontiers in Immunology
  • European Journal of Immunology
  • JCI Insight
  • Cellular Immunology
  • Trillium Immunologie

Manfred B. Lutz has collaborated regularly with a number of co-authors, including:

  • Haisam Alattar
  • Laura Cyran
  • Andreas Beilhack
  • Nelita du Plessis
  • I Eckert

Best Publications

  • An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow.

    M. B. Lutz;N. Kukutsch;A. L. J. Ogilvie;S. Rössner

  • Nomenclature of monocytes and dendritic cells in blood.

    Loems Ziegler-Heitbrock;Petronela Ancuta;Suzanne Crowe;Marc Dalod;Marc Dalod

  • Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?

    Manfred B Lutz;Gerold Schuler

  • The Conduit System Transports Soluble Antigens from the Afferent Lymph to Resident Dendritic Cells in the T Cell Area of the Lymph Node

    Michael Sixt;Nobuo Kanazawa;Manuel Selg;Thomas Samson

  • Repetitive Injections of Dendritic Cells Matured with Tumor Necrosis Factor α Induce Antigen-specific Protection of Mice from Autoimmunity

    Mauritius Menges;Susanne Rößner;Constanze Voigtländer;Heike Schindler

  • Immature dendritic cells generated with low doses of GM‐CSF in the absence of IL‐4 are maturation resistant and prolong allograft survival in vivo

    M B Lutz;R M Suri;M Niimi;A L Ogilvie

  • Human CD4 CD25 Regulatory, Contact-dependent T Cells Induce Interleukin 10-producing, Contact-independent Type 1-like Regulatory T Cells

    Detlef Dieckmann;Cord Henrik Bruett;Heidi Ploettner;Manfred Bernhard Lutz

  • Immobilized chemokine fields and soluble chemokine gradients cooperatively shape migration patterns of dendritic cells

    Kathrin Schumann;Tim Lämmermann;Markus Bruckner;Daniel F. Legler

  • Matrix metalloproteinases 9 and 2 are necessary for the migration of Langerhans cells and dermal dendritic cells from human and murine skin.

    Gudrun Ratzinger;Patrizia Stoitzner;Susanne Ebner;Manfred B. Lutz

  • Myeloid‐derived suppressor cell activation by combined LPS and IFN‐γ treatment impairs DC development

    Verena Greifenberg;Eliana Ribechini;Susanne Rößner;Manfred B. Lutz

  • CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice

    Christian Weber;Svenja Meiler;Yvonne Döring;Miriam Koch

  • The production of IFN-gamma by IL-12/IL-18-activated macrophages requires STAT4 signaling and is inhibited by IL-4.

    Heike Schindler;Manfred B. Lutz;Martin Röllinghoff;Christian Bogdan

  • Subsets, expansion and activation of myeloid-derived suppressor cells

    Eliana Ribechini;Verena Greifenberg;Sarah Sandwick;Manfred B. Lutz

  • Dendritic cells process exogenous viral proteins and virus-like particles for class I presentation to CD8+ cytotoxic T lymphocytes

    Martin F. Bachmann;Manfre D. B. Lutz;Guy T. Layton;Stephen J. Harris

  • Myeloid dendritic cell precursors generated from bone marrow suppress T cell responses via cell contact and nitric oxide production in vitro

    Susanne Rössner;Constanze Voigtländer;Carsten Wiethe;Jens Hänig

  • Increased Frequency of Myeloid-derived Suppressor Cells during Active Tuberculosis and after Recent Mycobacterium tuberculosis Infection Suppresses T-Cell Function

    Nelita du Plessis;Laurianne Loebenberg;Magdalena Kriel;Florian von Groote-Bidlingmaier

  • Culture of bone marrow cells in GM-CSF plus high doses of lipopolysaccharide generates exclusively immature dendritic cells which induce alloantigen-specific CD4 T cell anergy in vitro.

    Manfred B. Lutz;Nicole A. Kukutsch;Mauritius Menges;Susanne Rößner

  • Skin-Derived Dendritic Cells Can Mediate Deletional Tolerance of Class I-Restricted Self-Reactive T Cells

    Jason Waithman;Rhys S. Allan;Hiroshi Kosaka;Hiroaki Azukizawa

  • Intracellular routes and selective retention of antigens in mildly acidic cathepsin D/lysosome-associated membrane protein-1/MHC class II-positive vesicles in immature dendritic cells.

    M. B. Lutz;P. Rovere;M. J. Kleijmeer;M. Rescigno

  • Differential Functions of IL-4 Receptor Types I and II for Dendritic Cell Maturation and IL-12 Production and Their Dependency on GM-CSF

    Manfred B. Lutz;Markus Schnare;Mauritius Menges;Susanne Rössner

Frequent Co-Authors

Gerold Schuler
Gerold Schuler University of Erlangen-Nuremberg
Alexander Steinkasserer
Alexander Steinkasserer University of Erlangen-Nuremberg
Gerhard Walzl
Gerhard Walzl Stellenbosch University
Nikolaus Romani
Nikolaus Romani Innsbruck Medical University
Pieter J. M. Leenen
Pieter J. M. Leenen Erasmus University Rotterdam
Patrizia Stoitzner
Patrizia Stoitzner Innsbruck Medical University
Paola Ricciardi-Castagnoli
Paola Ricciardi-Castagnoli Toscana Life Sciences Foundation
Thomas Reinheckel
Thomas Reinheckel University of Freiburg
Harald Wajant
Harald Wajant University of Würzburg
Michael Sixt
Michael Sixt Institute of Science and Technology Austria

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