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Immunology

D-Index
50
Citations
15357
World Ranking
4189
National Ranking
1911

Overview

Joan E. Durbin is affiliated with Rutgers, The State University of New Jersey in the United States. Their research primarily focuses on the fields of Medicine and Immunology and Microbiology, with subfields including Epidemiology, Immunology, Infectious Diseases, and Pulmonary and Respiratory Medicine. The scientist's work covers several interconnected topics related to respiratory viral infections and immune system responses.

Durbin's main research topics include:

  • Respiratory viral infections research
  • Interferon and immune responses
  • Immune response and inflammation
  • Influenza virus research studies
  • Pneumonia and respiratory infections
  • COVID-19 clinical research studies
  • SARS-CoV-2 and COVID-19 research

Their recent published papers showcase a focus on viral infections and immune mechanisms:

  • "COVID-19 and emerging viral infections: The case for interferon lambda" (2020), published in The Journal of Experimental Medicine
  • "Critical role of interferons in gastrointestinal injury repair" (2021), published in Nature Communications
  • "The In Vivo Source of Type I and Type III IFNs is Pathogen Dependent" (2021), published in bioRxiv (Cold Spring Harbor Laboratory)
  • "An intranasal recombinant NDV-BRSV Fopt vaccine is safe and reduces lesion severity in a colostrum-deprived calf model of RSV infection" (2022), published in Scientific Reports
  • "Influenza A Virus Inhibits Alveolar Fluid Clearance in BALB/c Mice" (2020), published in UNC Libraries

The frequent co-authors of Joan E. Durbin include:

  • Sergei V. Kotenko
  • Amariliz Rivera
  • Russell K. Durbin
  • Vanessa Espinosa
  • Jian-Da Lin

Durbin's research has been disseminated through various publication venues, reflecting a diverse range of peer-reviewed journals and repositories:

  • The Journal of Experimental Medicine
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • UNC Libraries

Overall, Joan E. Durbin's contributions focus on understanding immune responses and viral pathogenesis, particularly within respiratory and gastrointestinal contexts. The overlap between interferon signaling pathways and clinical infectious diseases forms a central theme in their scholarly output.

Best Publications

  • Targeted Disruption of the Mouse Stat1 Gene Results in Compromised Innate Immunity to Viral Disease

    Joan E Durbin;Renée Hackenmiller;M.Celeste Simon;David E Levy

  • Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems

    Adolfo García-Sastre;Andrej Egorov;Demetrius Matassov;Sabine Brandt

  • Differential viral induction of distinct interferon-α genes by positive feedback through interferon regulatory factor-7

    Isabelle Marié;Joan E. Durbin;David E. Levy

  • VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents

    David F Stojdl;Brian D Lichty;Benjamin R tenOever;Jennifer M Paterson

  • Coordinated and distinct roles for IFN-alpha beta, IL-12, and IL-15 regulation of NK cell responses to viral infection.

    Khuong B. Nguyen;Thais P. Salazar-Mather;Marc Y Dalod;Jeffrey B. Van Deusen

  • Fatal Leukemia in Interleukin 15 Transgenic Mice Follows Early Expansions in Natural Killer and Memory Phenotype Cd8+ T Cells

    Todd A. Fehniger;Kazuhiro Suzuki;Anand Ponnappan;Jeffrey B. VanDeusen

  • Human Cytomegalovirus Inhibits Major Histocompatibility Complex Class II Expression By Disruption of the Jak/Stat Pathway

    Daniel M. Miller;Brian M. Rahill;Jeremy M. Boss;Michael Dale Lairmore

  • The Role of Interferon in Influenza Virus Tissue Tropism

    Adolfo García-Sastre;Russell K. Durbin;Hongyong Zheng;Peter Palese

  • Interferon alpha/beta-mediated inhibition and promotion of interferon gamma: STAT1 resolves a paradox.

    Khuong B. Nguyen;Leslie P. Cousens;Lesley A. Doughty;Gary C. Pien

  • Induction and function of type I and III interferon in response to viral infection

    David E Levy;Isabelle J Marié;Joan E Durbin

  • Type I IFN Modulates Innate and Specific Antiviral Immunity

    J E Durbin;A Fernandez-Sesma;C K Lee;T D Rao

  • Lambda Interferon Is the Predominant Interferon Induced by Influenza A Virus Infection In Vivo

    Nancy A. Jewell;Troy Cline;Sara E. Mertz;Sergey V. Smirnov

  • Interferon induction and function at the mucosal surface

    Russell K. Durbin;Sergei V. Kotenko;Joan E. Durbin

  • Recovery of Paramyxovirus Simian Virus 5 with a V Protein Lacking the Conserved Cysteine-rich Domain: The Multifunctional V Protein Blocks both Interferon-β Induction and Interferon Signaling

    Biao He;Reay G. Paterson;Nicola Stock;Joan E. Durbin

  • Plasticity and Virus Specificity of the Airway Epithelial Cell Immune Response during Respiratory Virus Infection

    Ioannis Ioannidis;Beth McNally;Meredith Willette;Mark E. Peeples;Mark E. Peeples

  • The Role of IFN in Respiratory Syncytial Virus Pathogenesis

    Joan E. Durbin;Joan E. Durbin;Teresa R. Johnson;Russell K. Durbin;Russell K. Durbin;Sara E. Mertz;Sara E. Mertz

  • Differential Type I Interferon Induction by Respiratory Syncytial Virus and Influenza A Virus In Vivo

    Nancy A. Jewell;Negin Vaghefi;Sara E. Mertz;Parvis Akter

  • COVID-19 and emerging viral infections: The case for interferon lambda.

    Ludmila Prokunina-Olsson;Noémie Alphonse;Noémie Alphonse;Ruth E. Dickenson;Joan E. Durbin

  • Acute phase response factor and additional members of the interferon-stimulated gene factor 3 family integrate diverse signals from cytokines, interferons, and growth factors.

    R Raz;J E Durbin;D E Levy

  • Type III interferon is a critical regulator of innate antifungal immunity

    Vanessa Espinosa;Orchi Dutta;Constance McElrath;Peicheng Du

  • RAPID COMMUNICATION Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems

    Adolfo Garcõ Âa-Sastre;Andrej Egorov;Demetrius Matassov;Sabine Brandt

Frequent Co-Authors

David E. Levy
David E. Levy New York University
R. Stokes Peebles
R. Stokes Peebles Vanderbilt University
Christine A. Biron
Christine A. Biron Brown University
Michael A. Caligiuri
Michael A. Caligiuri City Of Hope National Medical Center
Lauren O. Bakaletz
Lauren O. Bakaletz The Ohio State University
Adolfo García-Sastre
Adolfo García-Sastre Icahn School of Medicine at Mount Sinai
Robert A. Lamb
Robert A. Lamb Northwestern University
Abhay R. Satoskar
Abhay R. Satoskar The Ohio State University
Antonis E. Koromilas
Antonis E. Koromilas McGill University
Mark E. Peeples
Mark E. Peeples The Ohio State University

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