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Hisakata Yamada

Hisakata Yamada

D-Index & Metrics

Immunology

D-Index
44
Citations
7875
World Ranking
4775
National Ranking
184

Overview

Hisakata Yamada is affiliated with Kyushu University in Japan and has contributed extensively to the fields of Medicine and Immunology and Microbiology. Their research primarily focuses on Immunology, Rheumatology, Radiology, Nuclear Medicine and Imaging, Oncology, and Immunology and Allergy.

The main topics covered in Yamada's work include:

  • Rheumatoid Arthritis Research and Therapies
  • T-cell and B-cell Immunology
  • Monoclonal and Polyclonal Antibodies Research
  • Systemic Lupus Erythematosus Research
  • Immunotherapy and Immune Responses
  • Immune cells in cancer
  • Lymphoma Diagnosis and Treatment

Yamada has published in several scientific journals with notable frequency in these venues:

  • Modern Rheumatology
  • Immunological Medicine
  • The Journal of Immunology
  • Cancer Immunology Immunotherapy
  • Frontiers in Immunology

Selected recent papers by Yamada demonstrate research into T-cell immunology and autoimmune conditions, including rheumatoid arthritis. Examples of these papers are:

  • "Activation of TLR4 signaling inhibits progression of osteosarcoma by stimulating CD8-positive cytotoxic lymphocytes," 2020, Cancer Immunology Immunotherapy
  • "Autoreactivity of Peripheral Helper T Cells in the Joints of Rheumatoid Arthritis," 2021, The Journal of Immunology
  • "Human PD-1hiCD8+ T Cells Are a Cellular Source of IL-21 in Rheumatoid Arthritis," 2021, Frontiers in Immunology
  • "Type 1 helper T cells generate CXCL9/10-producing T-bet+ effector B cells potentially involved in the pathogenesis of rheumatoid arthritis," 2020, Cellular Immunology
  • "The Search for the Pathogenic T Cells in the Joint of Rheumatoid Arthritis: Which T-Cell Subset Drives Autoimmune Inflammation?," 2023, International Journal of Molecular Sciences

The scientist has collaborated frequently with a number of colleagues, including Toshifumi Fujiwara, Hiroaki Niiro, Yukio Akasaki, Yasuharu Nakashima, and Daisuke Hara, each with multiple joint publications.

Best Publications

  • Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

    Eri Taniguchi Ishikawa;Tetsuaki Ishikawa;Tetsuaki Ishikawa;Yasu S Morita;Kenji Toyonaga

  • Resident Vδ1+ γδ T Cells Control Early Infiltration of Neutrophils after Escherichia coli Infection via IL-17 Production

    Kensuke Shibata;Hisakata Yamada;Hiromitsu Hara;Kenji Kishihara

  • The Cytokine RANKL Produced by Positively Selected Thymocytes Fosters Medullary Thymic Epithelial Cells that Express Autoimmune Regulator

    Yu Hikosaka;Takeshi Nitta;Izumi Ohigashi;Kouta Yano

  • Th1 but not Th17 cells predominate in the joints of patients with rheumatoid arthritis

    Hisakata Yamada;Yasuharu Nakashima;Ken Okazaki;Taro Mawatari

  • C-type lectin MCL is an FcRγ-coupled receptor that mediates the adjuvanticity of mycobacterial cord factor.

    Yasunobu Miyake;Kenji Toyonaga;Daiki Mori;Shigeru Kakuta

  • Identification of CD25+ γδ T Cells As Fetal Thymus-Derived Naturally Occurring IL-17 Producers

    Kensuke Shibata;Hisakata Yamada;Risa Nakamura;Xun Sun

  • The molecular pathogenesis of collagen-induced arthritis in mice--a model for rheumatoid arthritis.

    Rikard Holmdahl;Robert Bockermann;Johan Bäcklund;Hisakata Yamada

  • Glucocorticoids Drive Diurnal Oscillations in T Cell Distribution and Responses by Inducing Interleukin-7 Receptor and CXCR4

    Akihiro Shimba;Guangwei Cui;Shizue Tani-ichi;Makoto Ogawa

  • The LTB4-BLT1 Axis Mediates Neutrophil Infiltration and Secondary Injury in Experimental Spinal Cord Injury

    Hirokazu Saiwai;Yasuyuki Ohkawa;Hisakata Yamada;Hiromi Kumamaru

  • Macrophage Infiltration Predicts a Poor Prognosis for Human Ewing Sarcoma

    Toshifumi Fujiwara;Jun-ichi Fukushi;Shunsaku Yamamoto;Yoshihiro Matsumoto

  • Notch-Hes1 pathway is required for the development of IL-17-producing γδ T cells.

    Kensuke Shibata;Hisakata Yamada;Tetsuya Sato;Takashi Dejima

  • Type I interferon limits influenza virus-induced acute lung injury by regulation of excessive inflammation in mice

    Yojiro Arimori;Risa Nakamura;Hisakata Yamada;Kensuke Shibata

  • Ly6C+Ly6G− Myeloid‐derived suppressor cells play a critical role in the resolution of acute inflammation and the subsequent tissue repair process after spinal cord injury

    Hirokazu Saiwai;Hiromi Kumamaru;Yasuyuki Ohkawa;Kensuke Kubota

  • Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation

    Kazuhito Gotoh;Yoshihiko Tanaka;Akihiko Nishikimi;Risa Nakamura

  • Tyrosine Kinase 2 Plays Critical Roles in the Pathogenic CD4 T Cell Responses for the Development of Experimental Autoimmune Encephalomyelitis

    Akiko Oyamada;Hiori Ikebe;Momoe Itsumi;Hirokazu Saiwai

  • IL-17 production by γδ T cells is important for the antitumor effect of Mycobacterium bovis bacillus Calmette-Guérin treatment against bladder cancer.

    Ario Takeuchi;Takashi Dejima;Hisakata Yamada;Kensuke Shibata

  • IFN-γ–Producing and IL-17–Producing γδ T Cells Differentiate at Distinct Developmental Stages in Murine Fetal Thymus

    Kensuke Shibata;Hisakata Yamada;Masataka Nakamura;Shinya Hatano

  • Pristane, a Non-Antigenic Adjuvant, Induces MHC Class II-Restricted, Arthritogenic T Cells in the Rat

    Jens Holmberg;Jonatan Tuncel;Hisakata Yamada;Shemin Lu

  • Protective Role of Naturally Occurring Interleukin-17A-Producing γδ T Cells in the Lung at the Early Stage of Systemic Candidiasis in Mice

    Takashi Dejima;Kensuke Shibata;Hisakata Yamada;Hiromitsu Hara

  • Direct isolation and RNA-seq reveal environment-dependent properties of engrafted neural stem/progenitor cells

    Hiromi Kumamaru;Yasuyuki Ohkawa;Hirokazu Saiwai;Hisakata Yamada

  • Tyk2-Signaling Plays an Important Role in Host Defense against Escherichia coli through IL-23-Induced IL-17 Production by γδ T Cells

    Risa Nakamura;Kensuke Shibata;Hisakata Yamada;Kazuya Shimoda

Frequent Co-Authors

Yasunobu Yoshikai
Yasunobu Yoshikai Kyushu University
Yukihide Iwamoto
Yukihide Iwamoto Kyushu University
Kikuo Nomoto
Kikuo Nomoto Kyushu University
Eckhard R. Podack
Eckhard R. Podack University of Miami
Yoichiro Iwakura
Yoichiro Iwakura Tokyo University of Science
Seiji Naito
Seiji Naito Kyushu University
Yasuyuki Ohkawa
Yasuyuki Ohkawa Kyushu University
Koichi Akashi
Koichi Akashi Kyushu University
Kazuya Shimoda
Kazuya Shimoda University of Miyazaki
Hiroaki Niiro
Hiroaki Niiro Kyushu University

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