H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology D-index 59 Citations 12,290 172 World Ranking 1770 National Ranking 873

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Antibody

Eckhard R. Podack mainly investigates Cell biology, Cytotoxic T cell, Perforin, Immunology and Cytolysis. His Cell biology research is multidisciplinary, relying on both Natural killer T cell, Cell membrane, CD28, Lymphocyte and Membrane glycoproteins. Eckhard R. Podack combines subjects such as T cell, Gene expression, Molecular biology and CD8 with his study of Cytotoxic T cell.

Eckhard R. Podack has included themes like Cellular immunity, Granzyme B and CTL* in his Perforin study. His Immunology research includes elements of Natural killer cell and Cancer research. His work carried out in the field of Cytolysis brings together such families of science as MACPF, Lymphokine-activated killer cell, Biophysics, Lysis and Membrane protein.

His most cited work include:

  • Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice (1581 citations)
  • Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules (340 citations)
  • Structure and function of human perforin. (287 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Immunology, Perforin, Cytotoxic T cell, Cell biology and Molecular biology. Immunology is represented through his CD8, Immune system, T cell, Antigen and Antibody research. Eckhard R. Podack has researched Perforin in several fields, including Fas ligand, Natural killer cell and Cytolysis.

His Cytotoxic T cell study incorporates themes from Apoptosis, Cancer research and Lymphocyte. The Cell biology study combines topics in areas such as Natural killer T cell, IL-2 receptor, CTL* and MACPF. Eckhard R. Podack works mostly in the field of Molecular biology, limiting it down to topics relating to Cytokine and, in certain cases, Tumor necrosis factor alpha.

He most often published in these fields:

  • Immunology (44.20%)
  • Perforin (31.00%)
  • Cytotoxic T cell (25.07%)

What were the highlights of his more recent work (between 2012-2021)?

  • Immunology (44.20%)
  • Perforin (31.00%)
  • Immune system (16.98%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Immunology, Perforin, Immune system, Cell biology and T cell. Eckhard R. Podack regularly ties together related areas like Cytotoxic T cell in his Immunology studies. His Cytotoxic T cell research is multidisciplinary, incorporating elements of Molecular biology and Antigen.

His biological study spans a wide range of topics, including Infectious disease, Gene expression, Microbiology and Bacteria. His Cell biology research integrates issues from Experimental autoimmune encephalomyelitis, Complement membrane attack complex and Cytolysis. The study incorporates disciplines such as Tumor microenvironment, Spleen, Cancer research and Lymphocyte in addition to T cell.

Between 2012 and 2021, his most popular works were:

  • Immunological mechanisms of the antitumor effects of supplemental oxygenation. (253 citations)
  • Systemic oxygenation weakens the hypoxia and hypoxia inducible factor 1α-dependent and extracellular adenosine-mediated tumor protection (95 citations)
  • Pulmonary Nontuberculous Mycobacterial Infection. A Multisystem, Multigenic Disease. (84 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Antibody

Eckhard R. Podack spends much of his time researching Immunology, Microbiology, Perforin, Cell biology and Immune system. His Immunology study integrates concerns from other disciplines, such as Cytotoxic T cell and Cancer research. His Microbiology research also works with subjects such as

  • Ubiquitin ligase, NEDD8, Yersinia pseudotuberculosis and Ubiquitin most often made with reference to Effector,
  • MACPF that connect with fields like Innate immune system,
  • Cytolysis, Messenger RNA and Molecular biology most often made with reference to Intracellular.

His research in Perforin intersects with topics in Macrophage, RNA interference, Gene expression and Intracellular parasite. His Cell biology research incorporates themes from Complement membrane attack complex and FOXP3. His studies in Immune system integrate themes in fields like Candidate Gene Analysis, Bronchiectasis, Cystic fibrosis and Connective tissue, Pathology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

David Kägi;Birgit Ledermann;Kurt Bürki;Peter Seiler.
Nature (1994)

2521 Citations

Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules

Eckhard R. Podack;John Ding-E Young;Zanvil A. Cohn.
Proceedings of the National Academy of Sciences of the United States of America (1985)

525 Citations

Structure and function of human perforin.

Mathias G. Lichtenheld;Kristin J. Olsen;Ping Lu;David M. Lowrey.
Nature (1988)

438 Citations

Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity

John Ding E. Young;Hans Hengartner;Eckhard R. Podack;Zanvil A. Cohn.
Cell (1986)

420 Citations

Cytolytic T cell granules. Isolation, structural, biochemical, and functional characterization.

Eckhard R. Podack;Paula J. Konigsberg;Paula J. Konigsberg.
Journal of Experimental Medicine (1984)

418 Citations

The role of cell-mediated cytotoxicity in acute GVHD after MHC-matched allogeneic bone marrow transplantation in mice.

Matthew B. Baker;Norman H. Altman;Eckhard R. Podack;Robert B. Levy.
Journal of Experimental Medicine (1996)

395 Citations

A central role of perforin in cytolysis

Eckhard R. Podack;Hans Hengartner;Mathias G. Lichtenheld.
Annual Review of Immunology (1991)

383 Citations

Assembly of two types of tubules with putative cytolytic function by cloned natural killer cells

Eckhard R. Podack;Gunther Dennert.
Nature (1983)

329 Citations

Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation

Sunil S Metkar;Baikun Wang;Miguel Aguilar-Santelises;Srikumar M Raja.
Immunity (2002)

329 Citations

The ninth component of complement and the pore-forming protein (perforin 1) from cytotoxic T cells: structural, immunological, and functional similarities.

John Ding E. Young;Zanvil A. Cohn;Eckhard R. Podack.
Science (1986)

317 Citations

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