World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
51
Citations
7761
World Ranking
2515
National Ranking
170

Overview

Christine Sers is affiliated with Charité - University Medicine Berlin in Germany and has a significant body of research focused on medicine, particularly in oncology and molecular biology. Their work spans a variety of studies related to cancer research, with a notable emphasis on cancer genomics, diagnostics, and treatment strategies.

Their research topics cover a broad range of areas, including:

  • Cancer Genomics and Diagnostics
  • Colorectal Cancer Treatments and Studies
  • Cancer Cells and Metastasis
  • Neuroendocrine Tumor Research Advances
  • Lung Cancer Research Studies
  • Single-cell and spatial transcriptomics
  • Pancreatic and Hepatic Oncology Research

Christine Sers has published extensively in the following venues, indicating an established presence in both preprint and peer-reviewed journals:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Advances in Biological Regulation
  • Oncogene
  • Cell Reports

Key recent publications by Christine Sers include:

  • Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinoma, 2021, Oncogene
  • Mitogen-activated protein kinase activity drives cell trajectories in colorectal cancer, 2021, EMBO Molecular Medicine
  • Combination Therapies with CDK4/6 Inhibitors to Treat KRAS- Mutant Pancreatic Cancer, 2022, Cancer Research
  • Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers, 2020, Cell Reports
  • KRAS inhibitors: resistance drivers and combinatorial strategies, 2024, Trends in cancer

Frequent co-authors in Christine Sers' work include:

  • David Horst
  • Markus Morkel
  • Philip Bischoff
  • Nils Blüthgen
  • Dieter Beule

Their main fields of study are Medicine and Biochemistry, Genetics and Molecular Biology, with specific focus areas in Oncology, Molecular Biology, Cancer Research, Epidemiology, and Pulmonary and Respiratory Medicine. Research activity reflects ongoing contributions targeted at understanding cancer biology at molecular and clinical levels.

Best Publications

  • Caveolin-1 is down-regulated in human ovarian carcinoma and acts as a candidate tumor suppressor gene.

    Kai Wiechen;Luda Diatchenko;Alexander Agoulnik;K. Michael Scharff

  • A genome-wide survey of RAS transformation targets

    Johannes Zuber;Oleg I. Tchernitsa;Bernd Hinzmann;Anne-Chantal Schmitz

  • Down-Regulation of Caveolin-1, a Candidate Tumor Suppressor Gene, in Sarcomas

    Kai Wiechen;Christine Sers;Alexander Agoulnik;Katharina Arlt

  • Strong negative feedback from Erk to Raf confers robustness to MAPK signalling

    Raphaela Fritsche‐Guenther;Franziska Witzel;Franziska Witzel;Anja Sieber;Ricarda Herr

  • An Alu element-associated hypermethylation variant of the POMC gene is associated with childhood obesity.

    Peter Kuehnen;Mona Mischke;Susanna Wiegand;Christine Sers

  • Network quantification of EGFR signaling unveils potential for targeted combination therapy

    Bertram Klinger;Bertram Klinger;Anja Sieber;Raphaela Fritsche‐Guenther;Franziska Witzel;Franziska Witzel

  • Ras-mediated deregulation of the circadian clock in cancer.

    Angela Relógio;Philippe Thomas;Paula Medina-Pérez;Silke Reischl

  • A Helminth Immunomodulator Exploits Host Signaling Events to Regulate Cytokine Production in Macrophages

    Christian Klotz;Thomas Ziegler;Ana Sofia Figueiredo;Sebastian Rausch

  • HMGA2 gene is a promising target for ovarian cancer silencing therapy.

    Anastasia Malek;Elena Bakhidze;Aurelia Noske;Christine Sers

  • Similar but different: distinct roles for KRAS and BRAF oncogenes in colorectal cancer development and therapy resistance

    Markus Morkel;Pamela Riemer;Pamela Riemer;Hendrik Bläker;Christine Sers;Christine Sers

  • Growth-inhibitory activity and downregulation of the class II tumor-suppressor gene H-rev107 in tumor cell lines and experimental tumors.

    Christine Sers;Urban Emmenegger;Knut Husmann;Katharina Bucher

  • In the presence of bone marrow stromal cells human multiple myeloma cells become independent of the IL-6/gp130/STAT3 pathway

    Manik Chatterjee;Dirk Hönemann;Suzanne Lentzsch;Kurt Bommert

  • Nitric oxide mediates apoptosis induction selectively in transformed fibroblasts compared to nontransformed fibroblasts.

    Stefanie Heigold;Christine Sers;Wibke Bechtel;Boris Ivanovas

  • A 2015 update on predictive molecular pathology and its role in targeted cancer therapy: a review focussing on clinical relevance.

    M Dietel;K Jöhrens;M V Laffert;M Hummel

  • Personalized medicine and development of targeted therapies: The upcoming challenge for diagnostic molecular pathology. A review.

    Manfred Dietel;Christine Sers

  • Immunocytochemistry reveals RANKL expression of myeloma cells.

    Orhan Sezer;Ulrike Heider;Christian Jakob;Ivana Zavrski

  • Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinoma.

    Philip Bischoff;Philip Bischoff;Alexandra Trinks;Alexandra Trinks;Benedikt Obermayer;Jan Patrick Pett

  • KRAS genotyping of paraffin-embedded colorectal cancer tissue in routine diagnostics: comparison of methods and impact of histology.

    Wilko Weichert;Christiane Schewe;Annika Lehmann;Christine Sers

  • EGFR mutation detection in NSCLC—assessment of diagnostic application and recommendations of the German Panel for Mutation Testing in NSCLC

    Roland Penzel;Christine Sers;Yuan Chen;Ulrich Lehmann-Mühlenhoff

  • Loss of Gelsolin expression in human ovarian carcinomas.

    Aurelia Noske;Carsten Denkert;Hagen Schober;Christine Sers

Frequent Co-Authors

Reinhold Schäfer
Reinhold Schäfer Charité - University Medicine Berlin
Manfred Dietel
Manfred Dietel Charité - University Medicine Berlin
Johannes Zuber
Johannes Zuber Research Institute of Molecular Pathology
Ulf Leser
Ulf Leser Humboldt-Universität zu Berlin
Carsten Denkert
Carsten Denkert Philipp University of Marburg
Wilko Weichert
Wilko Weichert Technical University of Munich
Hanspeter Herzel
Hanspeter Herzel Humboldt-Universität zu Berlin
André Rosenthal
André Rosenthal Institute of Molecular Biotechnology
David Capper
David Capper Charité - University Medicine Berlin
Bernhard G. Herrmann
Bernhard G. Herrmann Max Planck Society

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Molecular Biology opens doors to a range of online degrees and career pathways in the USA. Many students start by earning a nursing degree and later advance with bridge programs. Programs like capella university vs wgu rn to bsn can help you compare different online RN to BSN options to find a pathway that matches your goals and study style.

Affordability is a key concern for many learners. Finding the cheapest bsn to msn online programs can make further education accessible without overwhelming debt. Many of the top online programs are offered by non profit universities, which often deliver high-quality education with flexible schedules.

Additionally, there are excellent options for active military, veterans, and their families. Discovering online colleges for military can ensure the support and flexibility needed to balance service and study. Whatever your route, online degrees in biology and healthcare can launch you into a rewarding career or pave the way for advanced research opportunities.

Best Scientists Citing Christine Sers

Trending Scientists

Recently Published Articles