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D-Index & Metrics

Engineering and Technology

D-Index
59
Citations
15942
World Ranking
2305
National Ranking
722

Overview

Bruno C. Hancock is affiliated with Pfizer in the United States and has contributed extensively to research in engineering, with a focus on pharmaceutical sciences and related subfields such as molecular biology, biomedical engineering, materials chemistry, pharmaceutical science, and spectroscopy.

The scientist's research prominently covers topics including drug solubility and delivery systems, crystallization and solubility studies, protein purification and stability, analytical chemistry and chromatography, computational drug discovery methods, crystallography and molecular interactions, and extraction and separation processes.

Bruno C. Hancock has published several papers in notable scientific journals. Selected recent papers include:

  • Prediction of the Relative Free Energies of Drug Polymorphs above Zero Kelvin (2020, Crystal Growth & Design)
  • The Role of Titanium Dioxide (E171) and the Requirements for Replacement Materials in Oral Solid Dosage Forms: An IQ Consortium Working Group Review (2022, Journal of Pharmaceutical Sciences)
  • A Comparison of Methods for Computing Relative Anhydrous-Hydrate Stability with Molecular Simulation (2022, Crystal Growth & Design)
  • Titanium Dioxide (E171 Grade) and the Search For Replacement Opacifiers and Colorants: Supplier Readiness Survey, Case Studies and Regulatory Perspective (2023, Journal of Pharmaceutical Sciences)
  • Patient Acceptability and Preferences for Solid Oral Dosage Form Drug Product Attributes: A Scoping Review (2024, Patient Preference and Adherence)

The scientist frequently collaborates with other researchers, with several coauthors appearing multiple times in their work. Notable collaborators include Geoffrey P. F. Wood, Eric Dybeck, Guangxu Sun, Michael A. Bellucci, and Shuhao Wen.

Bruno's research has been published mainly in these venues:

  • Journal of Pharmaceutical Sciences
  • Crystal Growth & Design
  • Patient Preference and Adherence
  • Molecular Pharmaceutics
  • International Journal of Pharmaceutics

Best Publications

  • Characteristics and Significance of the Amorphous State in Pharmaceutical Systems

    Bruno C. Hancock;George Zografi

  • What is the true solubility advantage for amorphous pharmaceuticals

    Bruno C. Hancock;Michael Parks

  • The relationship between the glass transition temperature and the water content of amorphous pharmaceutical solids.

    Bruno C. Hancock;George Zografi

  • Crystallization of Indomethacin from the Amorphous State below and above Its Glass Transition Temperature

    Minoru Yoshioka;Bruno C. Hancock;George Zografi

  • CHARACTERIZATION OF THE TIME SCALES OF MOLECULAR MOTION IN PHARMACEUTICALLY IMPORTANT GLASSES

    Sheri L. Shamblin;Xiaolin Tang;Liuquan Chang;Bruno C. Hancock

  • The use of solubility parameters in pharmaceutical dosage form design

    Bruno C. Hancock;Peter York;Raymond C. Rowe

  • Modelling the mechanical behaviour of pharmaceutical powders during compaction

    C.-Y. Wu;O.M. Ruddy;A.C. Bentham;B.C. Hancock

  • A modified Drucker-Prager Cap model for die compaction simulation of pharmaceutical powders

    L.H. Han;J.A. Elliott;A.C. Bentham;A. Mills

  • Differential scanning calorimetry: applications in drug development.

    Sophie-Dorothée Clas;Chad R. Dalton;Bruno C. Hancock

  • Process Modeling in the Pharmaceutical Industry using the Discrete Element Method

    William R. Ketterhagen;Mary T. am Ende;Bruno C. Hancock

  • Predicting discharge dynamics from a rectangular hopper using the discrete element method (DEM)

    Anshu Anand;Jennifer S. Curtis;Carl R. Wassgren;Bruno C. Hancock

  • Predicting the flow mode from hoppers using the discrete element method

    William R. Ketterhagen;Jennifer S. Curtis;Carl R. Wassgren;Bruno C. Hancock

  • Numerical and experimental investigation of capping mechanisms during pharmaceutical tablet compaction

    C.-Y. Wu;B.C. Hancock;A. Mills;A.C. Bentham

  • Molecular mobility of amorphous pharmaceuticals determined using differential scanning calorimetry

    Bruno C Hancock;Sheri L Shamblin

  • Granular segregation in discharging cylindrical hoppers: A discrete element and experimental study

    William R. Ketterhagen;Jennifer S. Curtis;Carl R. Wassgren;Angela Kong

  • Modeling granular segregation in flow from quasi-three-dimensional, wedge-shaped hoppers

    William R. Ketterhagen;Jennifer S. Curtis;Carl R. Wassgren;Bruno C. Hancock

  • The relative densities of pharmaceutical powders, blends, dry granulations, and immediate-release tablets

    Bruno C. Hancock;Joshua T. Colvin;Matthew P. Mullarney;Andrey V. Zinchuk

  • Interpretation of Relaxation Time Constants for Amorphous Pharmaceutical Systems

    Sheri L. Shamblin;Bruno C. Hancock;Yves Dupuis;Michael J. Pikal

  • The use of solution theories for predicting water vapor absorption by amorphous pharmaceutical solids: a test of the Flory-Huggins and Vrentas models.

    Bruno C. Hancock;George Zografi

  • A numerical study of granular shear flows of rod-like particles using the discrete element method

    Y. Guo;C. Wassgren;W. Ketterhagen;B. Hancock

  • A simple predictive model for the tensile strength of binary tablets

    Chuan-Yu Wu;Serena M. Best;A. Craig Bentham;Bruno C. Hancock

Frequent Co-Authors

Carl Wassgren
Carl Wassgren Purdue University West Lafayette
James A. Elliott
James A. Elliott University of Cambridge
George Zografi
George Zografi University of Wisconsin–Madison
Chuan-Yu Wu
Chuan-Yu Wu University of Surrey
Serena M. Best
Serena M. Best University of Cambridge
Peter York
Peter York University of Bradford
Michael J. Pikal
Michael J. Pikal University of Connecticut
Ruth E. Cameron
Ruth E. Cameron University of Cambridge
William Bonfield
William Bonfield University of Cambridge
Makoto Mark Taketo
Makoto Mark Taketo Kyoto University

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