World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
66
Citations
14478
World Ranking
1622
National Ranking
821

Overview

Charles P. Emerson is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research spans multiple domains within biochemistry, genetics, molecular biology, and medicine, with a focus on skeletal muscle physiology, genetic engineering, and related biomedical fields.

The main fields of study associated with Emerson include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these disciplines, Emerson's work covers a range of subfields such as molecular biology, epidemiology, oncology, physiology, and biomedical engineering.

  • Molecular Biology
  • Epidemiology
  • Oncology
  • Physiology
  • Biomedical Engineering

Their research topics demonstrate a focus on muscle-related physiology and disease mechanisms, as well as advances in genetic engineering technologies. Key topics include:

  • Muscle Physiology and Disorders
  • CRISPR and Genetic Engineering
  • Cytomegalovirus and herpesvirus research
  • RNA Research and Splicing
  • Pluripotent Stem Cells Research
  • Ubiquitin and proteasome pathways
  • Genomics and Chromatin Dynamics

Recent publications by Emerson reflect this diverse research interest. Selected papers include:

  • "p38 MAPKs - roles in skeletal muscle physiology, disease mechanisms, and as potential therapeutic targets," 2021, published in JCI Insight
  • "Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors," 2022, published in The CRISPR Journal
  • "Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration," 2022, published in Nature Communications
  • "iMyoblasts for ex vivo and in vivo investigations of human myogenesis and disease modeling," 2021, published in eLife
  • "Outcome Measures in Facioscapulohumeral Muscular Dystrophy Clinical Trials," 2022, published in Cells

Emerson has collaborated extensively with several frequent coauthors, indicating an active network of research partnerships. Notable collaborators include:

  • Dongsheng Guo
  • Katelyn Daman
  • Jing Yan
  • Lawrence J. Hayward
  • Kathryn R. Wagner

Their work appears most frequently in venues such as bioRxiv, Zenodo, and journals like JCI Insight, The CRISPR Journal, and Nature Communications.

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • JCI Insight
  • The CRISPR Journal
  • Nature Communications

Best Publications

  • Myogenic regulatory factors and the specification of muscle progenitors in vertebrate embryos.

    Mary Elizabeth Pownall;Marcus K. Gustafsson;Charles P. Emerson

  • Regulation of Wnt Signaling and Embryo Patterning by an Extracellular Sulfatase

    Gurtej K. Dhoot;Marcus K. Gustafsson;Xingbin Ai;Weitao Sun

  • Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling

    Natalia A. Riobó;Ke Lu;Xingbin Ai;Gwendolyn M. Haines

  • QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling

    Xingbin Ai;Anth-Tri Do;Olga Lozynska;Marion Kusche-Gullberg

  • 5-Azacytidine induction of stable mesodermal stem cell lineages from 10T1/2 cells: evidence for regulatory genes controlling determination.

    Stephen F. Konieczny;Charles P. Emerson

  • Coordinate regulation of contractile protein synthesis during myoblast differentiation

    Robert B. Devlin;Charles P. Emerson

  • Sonic hedgehog controls epaxial muscle determination through Myf5 activation.

    A.-G. Borycki;B. Brunk;S. Tajbakhsh;M. Buckingham

  • Myogenic lineage determination and differentiation: Evidence for a regulatory gene pathway

    Deborah F. Pinney;Sonia H. Pearson-White;Stephen F. Konieczny;Keith E. Latham

  • Myf5 is a direct target of long-range Shh signaling and Gli regulation for muscle specification.

    Marcus K. Gustafsson;Hua Pan;Deborah F. Pinney;Yongliang Liu

  • Activation of myosin synthesis in fusing and mononucleated myoblasts

    Charles P. Emerson;Suzanne K. Beckner

  • Control of somite patterning by Sonic hedgehog and its downstream signal response genes

    A.G. Borycki;L. Mendham;C.P. Emerson

  • Sequential activation of three myogenic regulatory genes during somite morphogenesis in quail embryos.

    Mary Elizabeth Pownall;Mary Elizabeth Pownall;Charles P. Emerson

  • Molecular Genetics of Myosin

    Charles P. Emerson;Sanford I. Bernstein

  • Protein Kinase C-δ and Mitogen-Activated Protein/Extracellular Signal–Regulated Kinase-1 Control GLI Activation in Hedgehog Signaling

    Natalia A. Riobo;Gwendolyn M. Haines;Charles P. Emerson

  • QSulf1, a heparan sulfate 6-O-endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogenesis

    Shouwen Wang;Xingbin Ai;Stephen D. Freeman;Mary E. Pownall

  • SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation

    Xingbin Ai;Toshio Kitazawa;Anh Tri Do;Marion Kusche-Gullberg

  • Pax3 functions in cell survival and in pax7 regulation.

    Anne-Gaelle Borycki;Jun Li;Fuzi Jin;Charles P. Emerson

  • Shh and Wnt signaling pathways converge to control Gli gene activation in avian somites.

    A. Borycki;A.M. Brown;C.P. Emerson

  • Gli2 and Gli3 have redundant and context-dependent function in skeletal muscle formation.

    Aileen McDermott;Marcus Gustafsson;Thomas Elsam;Chi-Chung Hui

  • Regulatory principles of developmental signaling.

    M. Freeman;J. B. Gurdon

Frequent Co-Authors

Oliver D. King
Oliver D. King University of Massachusetts Chan Medical School
Louis M. Kunkel
Louis M. Kunkel Boston Children's Hospital
Stephen F. Konieczny
Stephen F. Konieczny Purdue University West Lafayette
Zhiping Weng
Zhiping Weng University of Massachusetts Chan Medical School
Ulf Lindahl
Ulf Lindahl Uppsala University
Wen Xue
Wen Xue University of Massachusetts Chan Medical School
Clara Franzini-Armstrong
Clara Franzini-Armstrong University of Pennsylvania
Woodring E. Wright
Woodring E. Wright The University of Texas Southwestern Medical Center
Melissa J. Moore
Melissa J. Moore University of Massachusetts Chan Medical School

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