His primary areas of investigation include Virology, Virus, Flavivirus, Murray Valley encephalitis virus and Virulence. Mario Lobigs does research in Virology, focusing on Japanese encephalitis specifically. In Virus, Mario Lobigs works on issues like Microbiology, which are connected to Dengue fever.
His Flavivirus research includes elements of Vero cell, Signal peptidase, Peptide sequence, Dengue virus and Viral replication. Mario Lobigs focuses mostly in the field of Murray Valley encephalitis virus, narrowing it down to matters related to Viral entry and, in some cases, Tropism and Mutant protein. His studies in Encephalitis integrate themes in fields like Cytotoxic T cell and Neurotropic virus.
His primary scientific interests are in Virology, Flavivirus, Virus, Cytotoxic T cell and Immunology. His Virology study combines topics from a wide range of disciplines, such as Immune system and Virulence. Mario Lobigs interconnects Murray Valley encephalitis virus, Subgenomic mRNA, Peptide sequence, Neurotropic virus and Innate immune system in the investigation of issues within Flavivirus.
His study focuses on the intersection of Murray Valley encephalitis virus and fields such as Cleavage with connections in the field of Capsid. His biological study spans a wide range of topics, including Perforin and Microbiology. His research in Cytotoxic T cell intersects with topics in T cell and CD8.
The scientist’s investigation covers issues in Virology, Japanese encephalitis, Flavivirus, Immunology and Virus. His work carried out in the field of Virology brings together such families of science as Cytotoxic T cell, CD8, Immune system and Recombinant DNA. His studies deal with areas such as Natural killer cell and Viral encephalitis as well as Immune system.
As part of one scientific family, Mario Lobigs deals mainly with the area of Japanese encephalitis, narrowing it down to issues related to the Vaccination, and often Flavivirus Infections and DNA vaccination. Mario Lobigs has included themes like Phenotype, Interferon, STAT1 and Dengue virus in his Flavivirus study. His Virus research is multidisciplinary, relying on both Mutagenesis and Aedes.
His primary areas of investigation include Japanese encephalitis, Flavivirus, Immunology, Virology and Cytotoxic T cell. His research integrates issues of Antibody and Smallpox in his study of Flavivirus. His work deals with themes such as Viral Vaccine, Flavivirus Infections and DNA vaccination, which intersect with Smallpox.
In general Immunology, his work in Japanese encephalitis vaccine, Neutralizing antibody, Innate immune system and Adoptive cell transfer is often linked to Chemokine receptor CCR5 linking many areas of study. His research in Innate immune system intersects with topics in Granzyme, Viral encephalitis and Natural killer cell. His studies link Immune system with Cytotoxic T cell.
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CD8+ T Cells Mediate Recovery and Immunopathology in West Nile Virus Encephalitis
Yang Wang;Mario Lobigs;Eva Lee;Arno Müllbacher.
Journal of Virology (2003)
A Single Amino Acid Substitution in the West Nile Virus Nonstructural Protein NS2A Disables Its Ability To Inhibit Alpha/Beta Interferon Induction and Attenuates Virus Virulence in Mice
Wen Jun Liu;Xiang Ju Wang;David C. Clark;Mario Lobigs.
Journal of Virology (2006)
Mechanism of Virulence Attenuation of Glycosaminoglycan-Binding Variants of Japanese Encephalitis Virus and Murray Valley Encephalitis Virus
Eva Lee;Mario Lobigs.
Journal of Virology (2002)
DNA-based and alphavirus-vectored immunisation with prM and E proteins elicits long-lived and protective immunity against the flavivirus, Murray Valley encephalitis virus.
G. Colombage;R. Hall;M. Pavy;M. Lobigs.
Substitutions at the Putative Receptor-Binding Site of an Encephalitic Flavivirus Alter Virulence and Host Cell Tropism and Reveal a Role for Glycosaminoglycans in Entry
Eva Lee;Mario Lobigs.
Journal of Virology (2000)
Common E protein determinants for attenuation of glycosaminoglycan-binding variants of Japanese encephalitis and West Nile viruses.
Eva Lee;Roy A. Hall;Mario Lobigs.
Journal of Virology (2004)
Flavivirus premembrane protein cleavage and spike heterodimer secretion require the function of the viral proteinase NS3.
Proceedings of the National Academy of Sciences of the United States of America (1993)
Antiviral effect of the heparan sulfate mimetic, PI-88, against dengue and encephalitic flaviviruses
Eva Lee;Megan Pavy;Nicolie Young;Craig Freeman.
Antiviral Research (2006)
Host cell selection of murray valley encephalitis virus variants altered at an RGD sequence in the envelope protein and in mouse virulence
M. Lobigs;R. Usha;A. Nestorowicz;I.D. Marshall.
Lack of both Fas Ligand and Perforin Protects from Flavivirus-Mediated Encephalitis in Mice
Rosa M. Licon Luna;Eva Lee;Arno Müllbacher;Robert V. Blanden.
Journal of Virology (2002)
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