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Molecular Biology

D-Index
74
Citations
25024
World Ranking
1217
National Ranking
94

Research.com Recognitions

  • 2015 - Fellow of the Royal Society, United Kingdom

Overview

Bryan M. Turner is affiliated with the University of Birmingham in the United Kingdom. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology, Cancer Research, Genetics, and Plant Science. The scientist's work covers key topics including Genomics and Chromatin Dynamics, Epigenetics and DNA Methylation, Cancer-related gene regulation, RNA modifications and cancer, MicroRNA in disease regulation, Genetics and Neurodevelopmental Disorders, and RNA Research and Splicing.

Their recent publications demonstrate a focus on chromosomal and epigenetic regulation mechanisms across a variety of contexts. Notable papers include:

  • Histone modifications form a cell-type-specific chromosomal bar code that persists through the cell cycle (2021, Scientific Reports)
  • Morphine leads to global genome changes in H3K27me3 levels via a Polycomb Repressive Complex 2 (PRC2) self-regulatory mechanism in mESCs (2020, Clinical Epigenetics)
  • Epigenome changes in active and inactive Polycomb-group-controlled regions (2023, EMBO Reports)
  • Histone modifications form a cell-type-specific chromosomal bar code that modulates and maintains patterns of gene expression through the cell cycle (2020, bioRxiv [Cold Spring Harbor Laboratory])
  • Abstract Sun1003: A recombinant protein oxygen carrier with reduced nitric oxide scavenging as a blood substitute for resuscitation (2025, Circulation)

Frequent collaborators include John A. Halsall, Simon Andrews, Felix Krueger, Charlotte E. Rutledge, and Gabriella Ficz. These coauthors have contributed to multiple joint publications, reflecting sustained research partnerships.

The scientist has published numerous articles in recognized venues such as Scientific Reports, Clinical Epigenetics, EMBO Reports, bioRxiv (Cold Spring Harbor Laboratory), and Circulation.

Bryan M. Turner was awarded the Fellow of the Royal Society, United Kingdom in 2015, marking recognition from a major scientific institution.

Best Publications

  • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

    Xinsheng Nan;Huck-Hui Ng;Colin A. Johnson;Carol D. Laherty

  • MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex.

    Huck-Hui Ng;Yi Zhang;Brian Hendrich;Colin A Johnson

  • The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression

    Peter Jeppesen;Bryan M. Turner

  • The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote

    Dirk Schübeler;David M. MacAlpine;David Scalzo;Christiane Wirbelauer

  • HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription

    Stephen E. Rundlett;Andrew A. Carmen;Ryuji Kobayashi;Sergei Bavykin

  • Histone H4 isoforms acetylated at specific lysine residues define individual chromosomes and chromatin domains in Drosophila polytene nuclei.

    Bryan M. Turner;Andrew J. Birley;Jayne Lavender

  • Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3.

    Stephen E. Rundlett;Andrew A. Carmen;Noriyuki Suka;Bryan M. Turner

  • Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern.

    M Braunstein;R E Sobel;C D Allis;B M Turner

  • Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors.

    C A Bradbury;F L Khanim;R Hayden;C M Bunce

  • Defining an epigenetic code

    Bryan M. Turner

  • Transient Inhibition of Histone Deacetylation Alters the Structural and Functional Imprint at Fission Yeast Centromeres

    Karl Ekwall;Tim Olsson;Bryan M. Turner;Gwen Cranston

  • Expanded lysine acetylation specificity of Gcn5 in native complexes.

    Patrick A. Grant;Anton Eberharter;Sam John;Richard G. Cook

  • Histone acetylation and control of gene expression.

    Bryan M. Turner

  • Crosstalk between CARM1 methylation and CBP acetylation on histone H3.

    Sylvain Daujat;Uta-Maria Bauer;Vanya Shah;Bryan Turner

  • Essential and redundant functions of histone acetylation revealed by mutation of target lysines and loss of the Gcn5p acetyltransferase

    Wenzheng Zhang;James R. Bone;Diane G. Edmondson;Bryan M. Turner

  • Nuclear organization of mammalian genomes : Polar chromosome territories build up functionally distinct higher order compartments

    Nicolas Sadoni;Sabine Langer;Christine Fauth;Giorgio Bernardi

  • A unified phylogeny-based nomenclature for histone variants

    Paul B Talbert;Kami Ahmad;Geneviève Almouzni;Juan Ausió

  • Acetylated histone H4 on the male X chromosome is associated with dosage compensation in Drosophila.

    J R Bone;J Lavender;R Richman;M J Palmer

  • Histone modifications : signalling receptors and potential elements of a heritable epigenetic code

    Karl P Nightingale;Laura P O’Neill;Bryan M Turner

  • Epigenetic characterization of the early embryo with a chromatin immunoprecipitation protocol applicable to small cell populations

    Laura P O'Neill;Matthew D VerMilyea;Bryan M Turner

Frequent Co-Authors

Colin A. Johnson
Colin A. Johnson University of Leeds
Charles Craddock
Charles Craddock Queen Elizabeth Hospital Birmingham
Jeannie T. Lee
Jeannie T. Lee Harvard University
Adrian Bird
Adrian Bird University of Edinburgh
Ingo Schubert
Ingo Schubert Leibniz Association
robert feil
robert feil Centre national de la recherche scientifique, CNRS
Neil Brockdorff
Neil Brockdorff University of Oxford
Francesco Falciani
Francesco Falciani University of Liverpool
Huck-Hui Ng
Huck-Hui Ng Genome Institute of Singapore
Douglas R. Higgs
Douglas R. Higgs University of Oxford

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