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Medicine

D-Index
122
Citations
47768
World Ranking
3503
National Ranking
133

Overview

Wim A. Buurman is affiliated with Maastricht University in the Netherlands and specializes in the field of Medicine, with a focus on Physiology, Surgery, Molecular Biology, Cell Biology, and Epidemiology. Their research encompasses various topics, including bariatric surgery and outcomes, dietary effects on health, epigenetics and DNA methylation, endoplasmic reticulum stress and disease, autophagy in disease and therapy, as well as nutrition and health in aging.

The scientist's recent published works include:

  • The effects of bariatric surgery on clinical profile, DNA methylation, and ageing in severely obese patients (2020, Clinical Epigenetics)
  • Temporal Transcript Profiling Identifies a Role for Unfolded Protein Stress in Human Gut Ischemia-Reperfusion Injury (2021, Cellular and Molecular Gastroenterology and Hepatology)
  • Compromised intestinal integrity in older adults during daily activities: a pilot study (2021, BMC Geriatrics)
  • Aggravation of Anti-Myeloperoxidase Antibody-Induced Glomerulonephritis by Bacterial Lipopolysaccharide: Role of Tumor Necrosis Factor-α (2020, UNC Libraries)
  • Evaluating the safety of two human experimental intestinal ischemia reperfusion models: A retrospective observational study (2021, PLoS ONE)

Frequent co-authors collaborating with Wim A. Buurman are:

  • Joep Grootjans
  • Joep P. M. Derikx
  • Kaatje Lenaerts
  • Eliza Fraszczyk
  • Mirjam Luijten

Wim A. Buurman's studies have been featured in multiple publication venues, including:

  • Clinical Epigenetics
  • Cellular and Molecular Gastroenterology and Hepatology
  • BMC Geriatrics
  • UNC Libraries
  • PLoS ONE

The research covers several important topics within human health and disease mechanisms. Key areas of focus reflect the interaction between surgical interventions and cellular or molecular changes, especially related to bariatric surgery and aging, as well as stress responses in gut tissues. Their work also addresses the integrity of intestinal barriers in older adults and inflammatory responses in renal disease models.

Best Publications

  • Intestinal permeability – a new target for disease prevention and therapy

    Stephan C. Bischoff;Giovanni Barbara;Wim Buurman;Theo Ockhuizen

  • Evidence for a relation between metabolic derangements and increased levels of inflammatory mediators in a subgroup of patients with chronic obstructive pulmonary disease.

    A. M. W. J. Schols;W. A. Buurman;A. J. Staal-Van Den Brekel;M. A. Dentener

  • Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation

    Marc A.R.C. Daemen;Cornelis van ‘t Veer;Geertrui Denecker;Vincent H. Heemskerk

  • In vivo expression of Toll-like receptor 2 and 4 by renal epithelial cells: IFN-gamma and TNF-alpha mediated up-regulation during inflammation.

    Tim G. A. M. Wolfs;Wim A. Buurman;Annemarie van Schadewijk;Bart de Vries

  • Convergence and Amplification of Toll-Like Receptor (TLR) and Receptor for Advanced Glycation End Products (RAGE) Signaling Pathways via High Mobility Group B1 (HMGB1)

    Judy R van Beijnum;Wim A Buurman;Arjan W Griffioen

  • Human intestinal microbiota composition is associated with local and systemic inflammation in obesity

    Froukje J. Verdam;Susana Fuentes;Charlotte de Jonge;Erwin G. Zoetendal

  • Local and systemic inflammation in patients with chronic obstructive pulmonary disease: soluble tumor necrosis factor receptors are increased in sputum.

    Juanita H Vernooy;Mehmet Küçükaycan;Jan A Jacobs;Niels H Chavannes

  • Tumor Necrosis Factor (TNF)-α Inhibits Insulin Signaling through Stimulation of the p55 TNF Receptor and Activation of Sphingomyelinase

    Pascal Peraldi;Gökhan S. Hotamisligil;Wim A. Buurman;Morris F. White

  • Interleukin-6 Gene-Deficient Mice Show Impaired Defense against Pneumococcal Pneumonia

    Tom van der Poll;Christopher V. Keogh;Xavier Guirao;Wim A. Buurman

  • Impact of Blood Transfusions on Inflammatory Mediator Release in Patients Undergoing Cardiac Surgery

    Erik Fransen;Jos Maessen;Mieke Dentener;Nicole Senden

  • Involvement of CD14 in lipopolysaccharide-induced tumor necrosis factor-alpha, IL-6 and IL-8 release by human monocytes and alveolar macrophages.

    M. A. Dentener;V. Bazil;E. J. U. Von Asmuth;M. Ceska

  • Plasma tumor necrosis factor and mortality in critically ill septic patients.

    J. M. H. Debets;R. Kampmeijer;M. P. M. H. Van Der Linden;W. A. Buurman

  • Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA.

    Rudolf S. N. Fehrmann;Ritsert C. Jansen;Jan H. Veldink;Harm-Jan Westra

  • Exercise-induced splanchnic hypoperfusion results in gut dysfunction in healthy men

    Kim van Wijck;Kaatje Lenaerts;Luc J. C. van Loon;Wilbert H. M. Peters

  • Short chain fatty acids exchange across the gut and liver in humans measured at surgery.

    Johanne G. Bloemen;Koen Venema;Marcel C. van de Poll;Steven W. Olde Damink

  • Nutritional stimulation of cholecystokinin receptors inhibits inflammation via the vagus nerve.

    Misha D P Luyer;Jan Willem M Greve;M'hamed Hadfoune;Jan A Jacobs

  • Long-Term Intratracheal Lipopolysaccharide Exposure in Mice Results in Chronic Lung Inflammation and Persistent Pathology

    Juanita H. J. Vernooy;Mieke A. Dentener;Robert J. van Suylen;Wim A. Buurman

  • Endogenous IL-10 protects mice from death during septic peritonitis.

    T van der Poll;A Marchant;W A Buurman;L Berman

  • De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health

    Leah Eissing;Thomas Scherer;Thomas Scherer;Klaus Tödter;Uwe Knippschild

  • Increased leptin concentrations correlate with increased concentrations of inflammatory markers in morbidly obese individuals.

    F. van Dielen;C. van 't Veer;A.M.W.J. Schols;P.B. Soeters

Frequent Co-Authors

Cornelis H.C. Dejong
Cornelis H.C. Dejong Maastricht University
Emiel F.M. Wouters
Emiel F.M. Wouters Maastricht University
Marten H. Hofker
Marten H. Hofker University Medical Center Groningen
Cornelis van 't Veer
Cornelis van 't Veer University of Amsterdam
Annemie M. W. J. Schols
Annemie M. W. J. Schols Maastricht University
Luc J. C. van Loon
Luc J. C. van Loon Maastricht University
Ad A.M. Masclee
Ad A.M. Masclee Maastricht University
Jan Jacobs
Jan Jacobs KU Leuven
Dirk J. Gouma
Dirk J. Gouma University of Amsterdam
Lude Franke
Lude Franke University Medical Center Groningen

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