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Molecular Biology

D-Index
64
Citations
27678
World Ranking
1698
National Ranking
136

Overview

William R. Taylor is affiliated with The Francis Crick Institute in the United Kingdom. Their research intersects the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a primary focus on Cancer Research and related subfields.

Their published work covers multiple specialized areas, including:

  • Cancer Genomics and Diagnostics
  • Epigenetics and DNA Methylation
  • Pancreatic and Hepatic Oncology Research
  • Cancer-related molecular mechanisms research
  • RNA modifications and cancer
  • Colorectal Cancer Screening and Detection
  • RNA Research and Splicing

Frequent publication venues for William R. Taylor's research include:

  • Journal of Clinical Oncology
  • Gastroenterology
  • Cancer Research
  • Clinical Cancer Research
  • Gynecologic Oncology

Among recent scientific papers, notable publications are:

  • "Chronic circadian disruption modulates breast cancer stemness and immune microenvironment to drive metastasis in mice" (2020, Nature Communications)
  • "High Detection Rates of Pancreatic Cancer Across Stages by Plasma Assay of Novel Methylated DNA Markers and CA19-9" (2021, Clinical Cancer Research)
  • "Assessment of extracellular vesicle isolation methods from human stool supernatant" (2022, Journal of Extracellular Vesicles)
  • "Methylated DNA markers for plasma detection of ovarian cancer: Discovery, validation, and clinical feasibility" (2022, Gynecologic Oncology)
  • "Novel Methylated DNA Markers in the Surveillance of Colorectal Cancer Recurrence" (2020, Clinical Cancer Research)

The scientist collaborates regularly with a group of co-authors, including:

  • John B. Kisiel
  • Douglas W. Mahoney
  • Karen A. Doering
  • Kelli N. Burger
  • Patrick H. Foote

Best Publications

  • The rapid generation of mutation data matrices from protein sequences

    David T. Jones;William R. Taylor;Janet M. Thornton

  • A new approach to protein fold recognition.

    DT Jones;WR Taylor;JM Thornton

  • Role of the polycomb protein EED in the propagation of repressive histone marks

    Raphael Margueron;Neil Justin;Katsuhito Ohno;Miriam L. Sharpe

  • A model recognition approach to the prediction of all-helical membrane protein structure and topology.

    D. T. Jones;W. R. Taylor;J. M. Thornton

  • Protein structure alignment.

    William R. Taylor;Christine A. Orengo

  • A structural model for the retroviral proteases.

    Laurence H. Pearl;William R. Taylor;William R. Taylor

  • The classification of amino acid conservation

    William Ramsay Taylor

  • A sequence pattern common to T cell epitopes.

    J B Rothbard;W R Taylor

  • Prediction of protein secondary structure and active sites using the alignment of homologous sequences.

    Markéta J. Zvelebil;Geoffrey J. Barton;William R. Taylor;Michael J.E. Sternberg

  • A deeply knotted protein structure and how it might fold

    William R. Taylor

  • SSAP: sequential structure alignment program for protein structure comparison.

    Christine A. Orengo;William R. Taylor

  • Identification of protein sequence homology by consensus template alignment.

    William Ramsay Taylor

  • Location of 'continuous' antigenic determinants in the protruding regions of proteins.

    J.M. Thornton;M.S. Edwards;W.R. Taylor;D.J. Barlow

  • A rapid method of protein structure alignment.

    C.A. Orengo;W.R. Taylor

  • A flexible method to align large numbers of biological sequences

    William R. Taylor

  • Structure Comparison and Structure Patterns

    Ingvar Eidhammer;Inge Jonassen;William R. Taylor

  • Identification and classification of protein fold families

    C.A Orengo;T.P. Flores;W.R. Taylor;J.M. Thornton

  • Coevolving Protein Residues: Maximum Likelihood Identification and Relationship to Structure

    David D. Pollock;William R. Taylor;Nick Goldman

  • A mutation data matrix for transmembrane proteins

    D.T. Jones;D.T. Jones;W.R. Taylor;J.M. Thornton

  • Calcium binding domains and calcium-induced conformational transition of SPARC/BM-40/osteonectin, an extracellular glycoprotein expressed in mineralized and nonmineralized tissues.

    Juergen Engel;William Taylor;Mats Paulsson;Helene Sage

Frequent Co-Authors

David T. Jones
David T. Jones University College London
Janet M. Thornton
Janet M. Thornton European Bioinformatics Institute
Christine A. Orengo
Christine A. Orengo University College London
Michael J.E. Sternberg
Michael J.E. Sternberg Imperial College London
Jonathan P. Stoye
Jonathan P. Stoye The Francis Crick Institute
Jonathan B. Rothbard
Jonathan B. Rothbard 180 Life Sciences
Peter W. H. Holland
Peter W. H. Holland University of Oxford
Steven J. Gamblin
Steven J. Gamblin The Francis Crick Institute
Guojie Zhang
Guojie Zhang Zhejiang University
Tom L. Blundell
Tom L. Blundell University of Cambridge

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