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Immunology

D-Index
49
Citations
8633
World Ranking
4347
National Ranking
1976

Overview

Penelope A. Morel is affiliated with the University of Pittsburgh in the United States. Their research spans multiple disciplines including Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Within these domains, their work focuses notably on immunology, infectious diseases, molecular biology, oncology, and modeling and simulation.

The primary topics addressed in their publications include:

  • Immune Cell Function and Interaction
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • T-cell and B-cell Immunology
  • RNA Research and Splicing
  • COVID-19 Epidemiological Studies
  • Immune Cells in Cancer

Some of the frequent publication venues where Penelope A. Morel has contributed are:

  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Pathogens
  • Cancer Research Communications
  • Immunometabolism

The following is a selection of recent papers authored or co-authored by Morel along with their year of publication and publication venues:

  • COVID-19 virtual patient cohort suggests immune mechanisms driving disease outcomes (2021), PLoS Pathogens
  • Iterative community-driven development of a SARS-CoV-2 tissue simulator (2020), bioRxiv (Cold Spring Harbor Laboratory)
  • COVID-19 virtual patient cohort reveals immune mechanisms driving disease outcomes (2021), bioRxiv (Cold Spring Harbor Laboratory)
  • Synergism Between IL21 and Anti-PD-1 Combination Therapy is Underpinned by the Coordinated Reprogramming of the Immune Cellular Network in the Tumor Microenvironment (2023), Cancer Research Communications
  • Alternatively Spliced Variants of Murine CD247 Influence T Cell Development and Activation, Revealing the Importance of the CD3ζ C-Terminal Region (2023), The Journal of Immunology

Collaborations are a substantial component of Morel's research activities. Frequent co-authors include:

  • Ye Jin
  • Adrianne L. Jenner
  • Courtney L. Davis
  • Amber M. Smith
  • Morgan Craig

Best Publications

  • In vivo imaging platform for tracking immunotherapeutic cells

    Eric T Ahrens;Rafael Flores;Hongyan Xu;Penelope A Morel

  • Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study.

    Penelope A. Morel;Janice S. Dorman;John A. Todd;Hugh O. McDevitt

  • Dendritic cells mediate NK cell help for Th1 and CTL responses: two-signal requirement for the induction of NK cell helper function.

    Robbie B. Mailliard;Young Ik Son;Richard Redlinger;Patrick T. Coates

  • Fluorine-19 MRI for visualization and quantification of cell migration in a diabetes model.

    Mangala Srinivas;Penelope A. Morel;Lauren A. Ernst;David H. Laidlaw

  • Crossregulation between Th1 and Th2 cells.

    Penelope A. Morel;Timothy B. Oriss

  • Dendritic Cells Promote Macrophage Infiltration and Comprise a Substantial Proportion of Obesity-Associated Increases in CD11c+ Cells in Adipose Tissue and Liver

    Maja Stefanovic-Racic;Xiao Yang;Michael S. Turner;Benjamin S. Mantell

  • Receptor‐mediated endocytosis of iron‐oxide particles provides efficient labeling of dendritic cells for in vivo MR imaging

    E.T. Ahrens;M. Feili-Hariri;H. Xu;G. Genove

  • Immunotherapy of NOD mice with bone marrow-derived dendritic cells.

    Maryam Feili-Hariri;Xin Dong;Sean M. Alber;Simon C. Watkins

  • Dominant Role of Antigen Dose in CD4+Foxp3+ Regulatory T Cell Induction and Expansion

    Michael S. Turner;Lawrence P. Kane;Penelope A. Morel

  • T-bet and Eomesodermin Are Required for T Cell-Mediated Antitumor Immune Responses

    Yibei Zhu;Songguang Ju;Elizabeth Chen;Shao Dai

  • Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies.

    Terrance P. O'Hanlon;Danielle Mercatante Carrick;Ira N. Targoff;Frank C. Arnett

  • In vivo cytometry of antigen-specific t cells using 19F MRI.

    Mangala Srinivas;Michael S. Turner;Jelena M. Janjic;Penelope A. Morel

  • Negative regulation of FcϵRI signaling by FcγRII costimulation in human blood basophils

    Christopher L. Kepley;John C. Cambier;Penelope A. Morel;Don Lujan

  • Expression of Functional CD32 Molecules on Human NK Cells Is Determined by an Allelic Polymorphism of the FcγRIIC Gene

    Diana Metes;Linda K. Ernst;William H. Chambers;Andrei Sulica

  • Polarization of naive T cells into Th1 or Th2 by distinct cytokine-driven murine dendritic cell populations: implications for immunotherapy

    Maryam Feili-Hariri;Dewayne H. Falkner;Penelope A. Morel

  • Effector CD8+ T cells in systemic sclerosis patients produce abnormally high levels of interleukin-13 associated with increased skin fibrosis

    Patrizia Fuschiotti;Thomas A. Medsger;Penelope A. Morel

  • Co-aggregation of FcgammaRII with FcepsilonRI on human mast cells inhibits antigen-induced secretion and involves SHIP-Grb2-Dok complexes.

    Christopher L. Kepley;Sharven Taghavi;Graham A. Mackay;Daocheng Zhu

  • Crossregulation Between T Helper Cell (Th)1 and Th2: Inhibition of Th2 Proliferation by IFN-gamma Involves Interference With IL-1

    T B Oriss;S A McCarthy;B F Morel;M A Campana

  • FcγRIIa, Not FcγRIIb, Is Constitutively and Functionally Expressed on Skin-Derived Human Mast Cells

    Wei Zhao;Christopher L. Kepley;Penelope A. Morel;Lawrence M. Okumoto

  • The duration of T cell stimulation is a critical determinant of cell fate and plasticity.

    Natasa Miskov-Zivanov;Michael S. Turner;Lawrence P. Kane;Penelope A. Morel

  • Aspartic acid at position 57 of the DQ beta chain protects against type 1 diabetes: A family study

    P A Morel;J S Dorman;J A Todd;H O Mcdevitt

Frequent Co-Authors

David J. Tweardy
David J. Tweardy The University of Texas MD Anderson Cancer Center
Thomas A. Medsger
Thomas A. Medsger University of Pittsburgh
Ronald B. Herberman
Ronald B. Herberman University of Pittsburgh
Angus W. Thomson
Angus W. Thomson University of Pittsburgh
Leslie T. Cooper
Leslie T. Cooper Mayo Clinic
Frank C. Arnett
Frank C. Arnett The University of Texas Health Science Center at Houston
John D. Reveille
John D. Reveille The University of Texas Health Science Center at Houston
Lawrence P. Kane
Lawrence P. Kane University of Pittsburgh
Mary Carrington
Mary Carrington Ragon Institute of MGH, MIT and Harvard
John A. Todd
John A. Todd University of Oxford

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