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Patrick Matthys

Patrick Matthys

D-Index & Metrics

Immunology

D-Index
65
Citations
14696
World Ranking
2853
National Ranking
37

Overview

Patrick Matthys is affiliated with KU Leuven in Belgium and has made significant contributions in the fields of Medicine and Immunology and Microbiology, as reflected in 83 and 64 publications respectively. Their research largely focuses on Immunology, Infectious Diseases, Molecular Biology, Hematology, and Neurology, aligning with the diverse subfields covered across their work.

The scientist's research topics encompass a broad range of areas including Immune Cell Function and Interaction, COVID-19 Clinical Research Studies, SARS-CoV-2 and COVID-19 Research, Long-Term Effects of COVID-19, Immune Cells in Cancer, Autoimmune and Inflammatory Disorders Research, and Inflammasome and Immune Disorders. These topics reflect a strong emphasis on both infectious diseases and immune-related disorders.

Among Patrick Matthys's recent publications are notable papers such as:

  • Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages, 2021, Cell Research
  • Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity, 2021, Nature Communications
  • A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate, 2020, Nature
  • Multinucleated Giant Cells: Current Insights in Phenotype, Biological Activities, and Mechanism of Formation, 2022, Frontiers in Cell and Developmental Biology
  • The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation, 2020, Blood

Patrick Matthys frequently collaborates with several co-authors, including Carine Wouters, Bert Malengier-Devlies, Paul Proost, Kourosh Ahmadzadeh, and Amber De Visscher, indicating a network of sustained research partnerships.

Regarding publication venues, their work has appeared most frequently in:

  • Frontiers in Immunology (13 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (7 publications)
  • Arthritis & Rheumatology (3 publications)
  • Research Square (3 publications)
  • Nature Communications (2 publications)

Best Publications

  • Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1

    Aernout Luttun;Marc Tjwa;Lieve Moons;Yan Wu

  • Modes of action of Freund's adjuvants in experimental models of autoimmune diseases.

    Alfons Billiau;Patrick Matthys

  • Accelerated collagen-induced arthritis in IFN-gamma receptor-deficient mice.

    Kurt Vermeire;Hubertine Heremans;Michel Vandeputte;S Huang

  • Interferon-γ: A historical perspective

    Alfons Billiau;Patrick Matthys

  • Macrophage activation syndrome: characteristic findings on liver biopsy illustrating the key role of activated, IFN-γ-producing lymphocytes and IL-6- and TNF-α-producing macrophages

    An D. Billiau;Tania Roskams;Rita Van Damme-Lombaerts;Patrick Matthys

  • AMD3100, a potent and specific antagonist of the stromal cell-derived factor-1 chemokine receptor CXCR4, inhibits autoimmune joint inflammation in IFN-gamma receptor-deficient mice.

    Patrick Matthys;Sigrid Hatse;Kurt Vermeire;Anja Wuyts

  • Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages.

    Els Wauters;Pierre Van Mol;Abhishek Dinkarnath Garg;Sander Jansen

  • A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

    Mourad Matmati;Peggy Jacques;Jonathan Maelfait;Jonathan Maelfait;Eveline Verheugen

  • Proinflammatory role of the Th17 cytokine interleukin-22 in collagen-induced arthritis in C57BL/6 mice

    Lies Geboes;Laure Dumoutier;Hilde Kelchtermans;Evelien Schurgers

  • Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3 + regulatory T cells

    Wim Pierson;Bénédicte Cauwe;Antonia Policheni;Antonia Policheni;Susan M Schlenner

  • Immunomodulatory Properties of Interferon‐γ: An Updatea

    Alfons Billiau;Hubertine Heremans;Kurt Vermeire;Patrick Matthys

  • Cytokines and cachexia.

    Patrick Matthys;Alfons Billiau

  • Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity.

    L. Vanderbeke;P. Van Mol;Y. Van Herck;F. De Smet

  • How interferon-γ keeps autoimmune diseases in check

    Hilde Kelchtermans;Alfons Billiau;Patrick Matthys

  • Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-γ

    Hilde Kelchtermans;Bert De Klerck;Tania Mitera;Maarten Van Balen

  • Severe cachexia in mice inoculated with interferon‐γ‐producing tumor cells

    Patrick Matthys;Roger Dukmans;Paul Proost;Jo Van Damme

  • Hemophagocytic lymphohistiocytosis (HLH): A heterogeneous spectrum of cytokine-driven immune disorders

    Ellen Brisse;Carine H. Wouters;Patrick Matthys

  • Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis

    Evelien Schurgers;Hilde Kelchtermans;Tania Mitera;Lies Geboes

  • Ankylosing enthesitis, dactylitis, and onychoperiostitis in male DBA/1 mice: a model of psoriatic arthritis

    Rik Lories;Patrick Matthys;K de Vlam;I Derese

  • The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor

    Aikaterini S Papadopoulou;James Dooley;Michelle A Linterman;Wim Pierson

  • Anti-interferon-γ antibody treatment, growth of Lewis lung tumours in mice and tumour-associated cachexia

    Patrick Matthys;Hubertine Heremans;Ghislain Opdenakker;Alfons Billiau

  • Discriminating Mild from Critical COVID-19 by Innate and Adaptive Immune Single-cell Profiling of Bronchoalveolar Lavages

    Els Wauters;Pierre Van Mol;Abhishek D. Garg;Sander Jansen

Frequent Co-Authors

Alfons Billiau
Alfons Billiau Rega Institute for Medical Research
Hubertine Heremans
Hubertine Heremans Rega Institute for Medical Research
Adrian Liston
Adrian Liston University of Cambridge
Georges Leclercq
Georges Leclercq Ghent University
Paul Proost
Paul Proost KU Leuven
An Billiau
An Billiau KU Leuven
Johan Neyts
Johan Neyts Rega Institute for Medical Research
Robert Snoeck
Robert Snoeck KU Leuven

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