World's Best Scientists 2026 revealed!
Michael E. Calhoun

Michael E. Calhoun

D-Index & Metrics

Neuroscience

D-Index
33
Citations
10213
World Ranking
9390
National Ranking
3965

Overview

Michael E. Calhoun is affiliated with RevealDx in the United States and has contributed to research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans multiple subfields, including Molecular Biology, Physiology, Pulmonary and Respiratory Medicine, Cellular and Molecular Neuroscience, and Radiology, Nuclear Medicine and Imaging.

The main topics of their research include:

  • Alzheimer's disease research and treatments
  • Lung Cancer Diagnosis and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Protein Kinase Regulation and GTPase Signaling
  • Drug Transport and Resistance Mechanisms
  • Neuroscience and Neuropharmacology Research
  • Cholinesterase and Neurodegenerative Diseases

Michael E. Calhoun's recent scholarly papers illustrate their focus on neurodegenerative diseases, diagnostic imaging, and therapeutic interventions. These papers include:

  • "Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo" (2021, Journal of Medicinal Chemistry)
  • "Acute inhibition of the CNS-specific kinase TTBK1 significantly lowers tau phosphorylation at several disease relevant sites" (2020, PLoS ONE)
  • "Clinical Impact and Generalizability of a Computer-Assisted Diagnostic Tool to Risk-Stratify Lung Nodules With CT" (2022, Journal of the American College of Radiology)
  • "Longitudinal EEG model detects antisense oligonucleotide treatment effect and increased UBE3A in Angelman syndrome" (2022, Brain Communications)
  • "Radiomics in the evaluation of lung nodules: Intrapatient concordance between full-dose and ultra-low-dose chest computed tomography" (2021, Diagnostic and Interventional Imaging)

The research outputs have been published in several venues, which include:

  • Journal of Medicinal Chemistry
  • PLoS ONE
  • Journal of the American College of Radiology
  • Brain Communications
  • Diagnostic and Interventional Imaging

Collaboration has been a notable part of their career. Frequent co-authors include:

  • Channa Bao
  • Brenda Amaral
  • Gregory M. Dillon
  • Jaclyn L. Henderson
  • Kristopher King

Best Publications

  • Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

    Christine Sturchler-Pierrat;Dorothee Abramowski;Mairead Duke;Karl-Heinz Wiederhold

  • Aβ42‐driven cerebral amyloidosis in transgenic mice reveals early and robust pathology

    Rebecca Radde;Tristan Bolmont;Stephan A Kaeser;Janaky Coomaraswamy

  • Neuron number and size in prefrontal cortex of children with autism

    Eric Courchesne;Peter R. Mouton;Michael E. Calhoun;Katerina Semendeferi

  • Neuron loss in APP transgenic mice

    Michael E. Calhoun;Karl-Heinz Wiederhold;Dorothee Abramowski;Amie L. Phinney

  • Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance.

    Tristan Bolmont;Florent Haiss;Daniel Eicke;Rebecca Radde

  • Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid

    Michael E. Calhoun;Patrick Burgermeister;Amie L. Phinney;Martina Stalder

  • Comparative evaluation of synaptophysin-based methods for quantification of synapses.

    Michael E. Calhoun;Mathias Jucker;Lee J. Martin;Gopal Thinakaran

  • Age and gender effects on microglia and astrocyte numbers in brains of mice.

    Peter R Mouton;Jeffrey M Long;De-Liang Lei;Victor Howard

  • Spontaneous Hemorrhagic Stroke in a Mouse Model of Cerebral Amyloid Angiopathy

    David T. Winkler;Luca Bondolfi;Martin C. Herzig;Lukas Jann

  • Hippocampal neuron and synaptophysin-positive bouton number in aging C57BL/6 mice.

    Michael E Calhoun;Daniel Kurth;Amie L Phinney;Jeffrey M Long

  • Amyloid-Associated Neuron Loss and Gliogenesis in the Neocortex of Amyloid Precursor Protein Transgenic Mice

    Luca Bondolfi;Michael Calhoun;Florian Ermini;H. Georg Kuhn

  • Cerebral Amyloid Induces Aberrant Axonal Sprouting and Ectopic Terminal Formation in Amyloid Precursor Protein Transgenic Mice

    Amie L. Phinney;Thomas Deller;Martina Stalder;Michael E. Calhoun

  • VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects

    Christopher R. Heier;Jesse M. Damsker;Qing Yu;Blythe C. Dillingham

  • Cholinergic changes in the APP23 transgenic mouse model of cerebral amyloidosis.

    Sonia Boncristiano;Michael E. Calhoun;Peter H. Kelly;Michelle Pfeifer

  • Stereological analysis of astrocyte and microglia in aging mouse hippocampus.

    Jeffrey M Long;Audrey N Kalehua;Nancy J Muth;Michael E Calhoun

  • Activity-regulated cytoskeletal-associated protein is localized to recently activated excitatory synapses.

    D. E. Moga;M. E. Calhoun;A. Chowdhury;P. Worley

  • Cognitive decline strongly correlates with cortical atrophy in Alzheimer’s dementia

    Peter R Mouton;Lee J Martin;Michael E Calhoun;Gloria Dal Forno

  • Long-term in vivo imaging of β-amyloid plaque appearance and growth in a mouse model of cerebral β-amyloidosis.

    Jasmin K. Hefendehl;Bettina M. Wegenast-Braun;Christian Liebig;Daniel Eicke

  • No hippocampal neuron or synaptic bouton loss in learning-impaired aged β-Amyloid precursor protein-null mice

    A.L. Phinney;M.E. Calhoun;D.P. Wolfer;H.-P. Lipp

  • Stereological estimation of total microglia number in mouse hippocampus

    Jeffrey M. Long;Audrey N. Kalehua;Nancy J. Muth;John M. Hengemihle

  • Mechanisms of cerebrovascular amyloid deposition. Lessons from mouse models.

    Patrick Burgermeister;Michael E. Calhoun;David T. Winkler;Mathias Jucker

Frequent Co-Authors

Mathias Jucker
Mathias Jucker University of Tübingen
Matthias Staufenbiel
Matthias Staufenbiel University of Tübingen
Peter R. Rapp
Peter R. Rapp National Institutes of Health
Susana Martinez-Conde
Susana Martinez-Conde SUNY Downstate Medical Center
Jorge Otero-Millan
Jorge Otero-Millan Johns Hopkins University
Stephen L. Macknik
Stephen L. Macknik SUNY Downstate Medical Center
Jong M. Rho
Jong M. Rho University of California, San Diego
Lee J. Martin
Lee J. Martin Johns Hopkins University School of Medicine
Shinichi Kohsaka
Shinichi Kohsaka Keio University
William D. Hopkins
William D. Hopkins University of Wisconsin–Madison

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Neuroscience studies often intersect with several adjacent fields, allowing you to tailor your education and career to your interests. Many students choose to broaden their expertise with degrees in psychology, counseling, or social work—all of which offer flexible online options. If you’re interested in the foundational aspects of human behavior, an online psychology degree is a popular first step that opens doors to various career pathways.

For those passionate about making a direct impact in communities, exploring an online master's in social work provides a route to clinical roles and advanced practice. If you are considering doctoral-level training, the cheapest psyd programs can help you pursue a career in professional psychology without heavy financial burdens.

Finally, for individuals drawn to the counseling professions, marriage and family therapy online programs accredited are a streamlined way to earn qualifications and begin meaningful work in therapeutic settings. Choosing any of these pathways diversifies your skill set and enhances your options in neuroscience-related careers.

Best Scientists Citing Michael E. Calhoun

Trending Scientists

Recently Published Articles