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Molecular Biology

D-Index
65
Citations
15771
World Ranking
1667
National Ranking
842

Overview

Martin W. Hetzer is affiliated with the Salk Institute for Biological Studies in the United States. Their research contributions span multiple areas within biochemistry, genetics, and molecular biology, with a substantial focus on molecular and cell biology. The scientist has published extensively, working primarily on topics related to nuclear structure and function, RNA research and splicing, genomics and chromatin dynamics, and cellular components such as the mitochondria and endoplasmic reticulum.

The main topics of their research include:

  • Nuclear Structure and Function
  • RNA Research and Splicing
  • Genomics and Chromatin Dynamics
  • Microtubule and mitosis dynamics
  • Mitochondrial Function and Pathology
  • Pancreatic function and diabetes
  • Endoplasmic Reticulum Stress and Disease

They have contributed to the fields of study as follows:

  • Biochemistry, Genetics and Molecular Biology

Within this broad field, Hetzer's work covers key subfields:

  • Molecular Biology
  • Cell Biology
  • Surgery
  • Aging
  • Pediatrics, Perinatology and Child Health

Their frequent co-authors highlight ongoing collaborative efforts with several researchers in related fields:

  • Ukrae Cho
  • Rafael Arrojo e Drigo
  • Simone Bersini
  • Maxim N. Shokhirev
  • Juliana S. Capitanio

Publications by Martin W. Hetzer have appeared in multiple scientific journals, with notable frequency in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Life Science Alliance
  • eLife
  • Genes & Development
  • Developmental Cell

Selected recent papers include:

  • Dynamic regulation of histone modifications and long-range chromosomal interactions during postmitotic transcriptional reactivation, 2020, Genes & Development
  • Identification of long-lived proteins in the mitochondria reveals increased stability of the electron transport chain, 2021, Developmental Cell
  • Aging compromises human islet beta cell function and identity by decreasing transcription factor activity and inducing ER stress, 2022, Science Advances
  • Nup93 regulates breast tumor growth by modulating cell proliferation and actin cytoskeleton remodeling, 2020, Life Science Alliance
  • Nuclear Periphery Takes Center Stage: The Role of Nuclear Pore Complexes in Cell Identity and Aging, 2020, Neuron

Best Publications

  • Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects

    Jerome Mertens;Apuã C.M. Paquola;Manching Ku;Emily Hatch

  • Catastrophic Nuclear Envelope Collapse in Cancer Cell Micronuclei

    Emily M. Hatch;Andrew H. Fischer;Thomas J. Deerinck;Martin W. Hetzer

  • Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells

    Maximiliano A. D'Angelo;Marcela Raices;Siler H. Panowski;Martin W. Hetzer

  • Identification of Long-Lived Proteins Reveals Exceptional Stability of Essential Cellular Structures

    Brandon H. Toyama;Jeffrey N. Savas;Sung Kyu Park;Michael S. Harris;Michael S. Harris

  • Structure, dynamics and function of nuclear pore complexes.

    Maximiliano A. D’Angelo;Martin W. Hetzer

  • Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes.

    Maya Capelson;Yun Liang;Roberta Schulte;William Mair

  • The Conserved Nup107-160 Complex Is Critical for Nuclear Pore Complex Assembly

    Tobias C Walther;Annabelle Alves;Helen Pickersgill;Isabelle Loïodice

  • The Nuclear Envelope

    Martin W. Hetzer

  • Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly

    Martin Hetzer;Hemmo H. Meyer;Tobias C. Walther;Daniel Bilbao-Cortes

  • Pushing the envelope: structure, function, and dynamics of the nuclear periphery.

    Martin W Hetzer;Tobias C Walther;Iain W Mattaj

  • Extremely Long-Lived Nuclear Pore Proteins in the Rat Brain

    Jeffrey N. Savas;Brandon H. Toyama;Tao Xu;John R. Yates

  • Cell Cycle-Dependent Differences in Nuclear Pore Complex Assembly in Metazoa

    Christine M. Doucet;Jessica A. Talamas;Martin W. Hetzer

  • Protein homeostasis: live long, won’t prosper

    Brandon H. Toyama;Martin W. Hetzer

  • GTP Hydrolysis by Ran Is Required for Nuclear Envelope Assembly

    Martin Hetzer;Daniel Bilbao-Cortés;Tobias C Walther;Oliver J Gruss

  • RanGTP mediates nuclear pore complex assembly

    Tobias C. Walther;Peter Askjaer;Marc Gentzel;Anja Habermann

  • Nucleolar expansion and elevated protein translation in premature aging.

    Abigail Buchwalter;Martin W. Hetzer

  • MEL-28/ELYS is required for the recruitment of nucleoporins to chromatin and postmitotic nuclear pore complex assembly

    Cerstin Franz;Rudolf Walczak;Sevil Yavuz;Rachel Santarella

  • Transient nuclear envelope rupturing during interphase in human cancer cells

    Jesse D. Vargas;Emily M. Hatch;Daniel J. Anderson;Martin W. Hetzer

  • The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly

    Martin Hetzer;Oliver J Gruss;Iain W Mattaj

  • Nuclear pores form de novo from both sides of the nuclear envelope.

    Maximiliano A. D'Angelo;Daniel J. Anderson;Erin Richard;Martin W. Hetzer

Frequent Co-Authors

Helmut Ritter
Helmut Ritter Heinrich Heine University Düsseldorf
Christopher Barner-Kowollik
Christopher Barner-Kowollik Queensland University of Technology
Bernhard V. K. J. Schmidt
Bernhard V. K. J. Schmidt University of Glasgow
Iain W. Mattaj
Iain W. Mattaj Human Technopole
Tobias C. Walther
Tobias C. Walther Harvard University
Christopher Benner
Christopher Benner University of California, San Diego
Fred H. Gage
Fred H. Gage Salk Institute for Biological Studies
Rudolf J. Schweyen
Rudolf J. Schweyen Max F. Perutz Laboratories
Mark H. Ellisman
Mark H. Ellisman University of California, San Diego
Thomas J. Deerinck
Thomas J. Deerinck University of California, San Diego

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