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Medicine

D-Index
73
Citations
23647
World Ranking
19574
National Ranking
9745

Overview

Mark Redston is affiliated with Brigham and Women's Hospital in the United States and has contributed extensively to medical research, particularly within the field of medicine and its surgical and pathological subdisciplines. Their work spans various aspects of gastroenterology, oncology, and pathology, focusing on genetic factors and cancer treatment outcomes.

The scientist's primary fields of study include Medicine broadly, with significant contributions in Surgery, Pulmonary and Respiratory Medicine, Pathology and Forensic Medicine, Oncology, and Gastroenterology.

Specific research topics associated with Mark Redston include:

  • Genetic factors in colorectal cancer
  • Gastric cancer management and outcomes
  • Esophageal cancer research and treatment
  • Colorectal and anal carcinomas
  • Colorectal cancer treatments and studies
  • Gastrointestinal tumor research and treatment
  • Eosinophilic esophagitis

Mark Redston has published papers in various reputable venues, with frequent publications in:

  • UNC Libraries
  • Gastroenterology
  • Journal of Pediatric Gastroenterology and Nutrition
  • Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
  • New England Journal of Medicine

Their notable recent publications include:

  • Abnormal TP53 Predicts Risk of Progression in Patients With Barrett's Esophagus Regardless of a Diagnosis of Dysplasia (2021, Gastroenterology)
  • Prevalence of Mismatch-Repair Deficiency in Rectal Adenocarcinomas (2022, New England Journal of Medicine)
  • Florid Foreign Body-type Giant Cell Response to Keratin Is Associated With Improved Overall Survival in Patients Receiving Preoperative Therapy for Esophageal Squamous Cell Carcinoma (2021, The American Journal of Surgical Pathology)
  • Clinical Presentation and Outcomes of Helicobacter heilmannii Gastritis in Children in the New England Region of the United States (2023, Journal of Pediatric Gastroenterology and Nutrition)
  • 42 ABNORMAL TP53 PREDICTS RISK OF PROGRESSION IN PATIENTS WITH BARRETT'S ESOPHAGUS REGARDLESS OF A DIAGNOSIS OF DYSPLASIA (2021, Gastroenterology)

Frequent collaborators include:

  • Amy Noffsinger
  • Matthew B. Yurgelun
  • Diane Stapleton
  • Richard H. Lash
  • Adam J. Bass

Mark Redston's body of work is closely tied to understanding cancer at the genetic and clinical levels, with particular attention to gastrointestinal cancers. Their research contributes data and findings on disease progression risks, therapeutic responses, and pathology related to esophageal and colorectal tumors.

Best Publications

  • Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer

    Christine M. Ribic;Daniel J. Sargent;Malcolm J. Moore;Malcolm J. Moore;Stephen N. Thibodeau

  • Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer.

    Robert Gryfe;Hyeja Kim;Eugene T.K. Hsieh;Melyssa D. Aronson

  • Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma.

    C Caldas;S A Hahn;L T da Costa;M S Redston

  • Celecoxib for the Prevention of Sporadic Colorectal Adenomas

    Monica M. Bertagnolli;Craig J. Eagle;Ann G. Zauber;Mark Redston

  • Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma.

    Andrew J. Aguirre;Nabeel Bardeesy;Manisha Sinha;Lyle Lopez

  • Immunohistochemistry Versus Microsatellite Instability Testing in Phenotyping Colorectal Tumors

    Noralane M. Lindor;Lawrence J. Burgart;Olga Leontovich;Richard M. Goldberg

  • Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse.

    Nabeel Bardeesy;Andrew J. Aguirre;Gerald C. Chu;Kuang Hung Cheng

  • p53 Mutations in Pancreatic Carcinoma and Evidence of Common Involvement of Homocopolymer Tracts in DNA Microdeletions

    M S Redston;C Caldas;A B Seymour;R H Hruban

  • Detection of K-ras mutations in the stool of patients with pancreatic adenocarcinoma and pancreatic ductal hyperplasia.

    Carlos Caldas;Stephan A. Hahn;Ralph H. Hruban;Mark S. Redston

  • Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803.

    Monica M. Bertagnolli;Donna Niedzwiecki;Carolyn C. Compton;Hejin P. Hahn

  • Examination of Mutations in BRAF, NRAS, and PTEN in Primary Cutaneous Melanoma

    Vikas K. Goel;Alexander J.F. Lazar;Alexander J.F. Lazar;Carla L. Warneke;Mark S. Redston;Mark S. Redston

  • MSH2 deficient mice are viable and susceptible to lymphoid tumours.

    A.H. Reitmair;R. Schmits;A. Ewel;B. Bapat

  • Pathology of Genetically Engineered Mouse Models of Pancreatic Exocrine Cancer: Consensus Report and Recommendations

    Ralph H. Hruban;N. Volkan Adsay;Jorge Albores-Saavedra;Miriam R. Anver

  • O6-Methylguanine DNA Methyltransferase Deficiency and Response to Temozolomide-Based Therapy in Patients with Neuroendocrine Tumors

    Matthew H. Kulke;Jason L. Hornick;Christine Frauenhoffer;Susanne Hooshmand

  • Pathology features in Bethesda guidelines predict colorectal cancer microsatellite instability: a population-based study.

    Mark A. Jenkins;Shinichi Hayashi;Anne Marie O'Shea;Lawrence J. Burgart

  • High-resolution characterization of the pancreatic adenocarcinoma genome

    Andrew J. Aguirre;Cameron Brennan;Gerald Bailey;Raktim Sinha

  • Allelotype of pancreatic adenocarcinoma using xenograft enrichment.

    Hahn Sa;Seymour Ab;Hoque At;Schutte M

  • Genetic, Immunohistochemical, and Clinical Features of Medullary Carcinoma of the Pancreas : A Newly Described and Characterized Entity

    Robb E. Wilentz;Michael Goggins;Mark Redston;Victoria A. Marcus

  • Immunohistochemistry for hMLH1 and hMSH2: a practical test for DNA mismatch repair-deficient tumors.

    Victoria A. Marcus;Lisa Madlensky;Robert Gryfe;Hyeja Kim

  • Molecular biology of colorectal cancer

    Robert Gryfe;Bharati Bapat;Steven Gallinger;Carol Swallow

Frequent Co-Authors

Steven Gallinger
Steven Gallinger Ontario Institute for Cancer Research
Monica M. Bertagnolli
Monica M. Bertagnolli Brigham and Women's Hospital
Scott E. Kern
Scott E. Kern Johns Hopkins University
Carlos Caldas
Carlos Caldas University of Cambridge
Charles J. Yeo
Charles J. Yeo Thomas Jefferson University
Ralph H. Hruban
Ralph H. Hruban Johns Hopkins University School of Medicine
Donna Niedzwiecki
Donna Niedzwiecki Duke University
Robert J. Mayer
Robert J. Mayer Dana-Farber Cancer Institute
Alexander J. Lazar
Alexander J. Lazar The University of Texas MD Anderson Cancer Center
Jason L. Hornick
Jason L. Hornick Brigham and Women's Hospital

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