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Medicine

D-Index
101
Citations
66350
World Ranking
7786
National Ranking
4057

Overview

Mark A. Mintun is a researcher affiliated with the University of Pennsylvania in the United States. The primary focus of their scientific work revolves around the study of Alzheimer's disease, dementia, and cognitive impairment, with significant contributions to understanding and developing treatments for these conditions.

Their research spans the field of medicine, with key subfields including psychiatry and mental health, physiology, molecular biology, cognitive neuroscience, and radiology, nuclear medicine, and imaging. This multidisciplinary approach supports a comprehensive exploration of neurodegenerative diseases and brain function.

Mark A. Mintun has published extensively on topics such as Alzheimer's disease research and treatments, dementia and cognitive impairment research, functional brain connectivity studies, health systems and economic evaluations related to quality of life, advanced neuroimaging techniques and applications, medical imaging techniques, and the role of cholinesterase in neurodegenerative diseases.

Frequent publication venues for their work include:

  • Alzheimer s & Dementia
  • Nature Communications
  • Scientific Reports
  • JAMA Neurology
  • Neurology

They have collaborated frequently with several co-authors, including:

  • John C. Morris
  • Adam Fleisher
  • Sonia Pawluczyk
  • Clifford R. Jack
  • Michael Donohue

Among their notable recent publications are:

  • "Donanemab in Early Alzheimer's Disease," 2021, New England Journal of Medicine
  • "Donanemab in Early Symptomatic Alzheimer Disease," 2023, JAMA
  • "Spread of pathological tau proteins through communicating neurons in human Alzheimer's disease," 2020, Nature Communications
  • "Positron Emission Tomography Imaging With [18F]flortaucipir and Postmortem Assessment of Alzheimer Disease Neuropathologic Changes," 2020, JAMA Neurology
  • "A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease," 2021, Nature Medicine

Best Publications

  • Improved assessment of significant activation in functional magnetic resonance imaging (fMRI) : use of a cluster-size threshold

    Steven D. Forman;Jonathan D. Cohen;Mark Fitzgerald;William F. Eddy

  • Positron emission tomographic studies of the cortical anatomy of single-word processing

    Steven E. Petersen;P. T. Fox;Michael I. Posner;M. Mintun

  • Molecular, Structural, and Functional Characterization of Alzheimer's Disease: Evidence for a Relationship between Default Activity, Amyloid, and Memory

    Randy L. Buckner;Abraham Z. Snyder;Benjamin J. Shannon;Gina LaRossa

  • Brain Work and Brain Imaging

    Marcus E Raichle;Mark A Mintun

  • Consensus nomenclature for in vivo imaging of reversibly binding radioligands

    Robert B. Innis;Vincent Joseph Cunningham;Jacques Delforge;Masahiro Fujita

  • Nonoxidative glucose consumption during focal physiologic neural activity

    Peter T. Fox;Marcus E. Raichle;Mark A. Mintun;Carmen Dence

  • Depression Duration But Not Age Predicts Hippocampal Volume Loss in Medically Healthy Women with Recurrent Major Depression

    Yvette I. Sheline;Milan Sanghavi;Mark A. Mintun;Mokhtar H. Gado

  • Spatial working memory in humans as revealed by PET

    John Jonides;Edward E. Smith;Robert A. Koeppe;Edward Awh

  • The default mode network and self-referential processes in depression

    Yvette I. Sheline;M Deanna;Joseph L. Price;Melissa M. Rundle

  • Positron emission tomographic studies of the processing of singe words

    Steven E. Petersen;Peter T. Fox;Michael I. Posner;Mark Mintun

  • Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans.

    Anne M. Fagan;Mark A. Mintun;Robert H. Mach;Sang-Yoon Lee

  • Increased amygdala response to masked emotional faces in depressed subjects resolves with antidepressant treatment: an fMRI study

    Yvette I. Sheline;M Deanna;Julie M. Donnelly;John M. Ollinger

  • Resting-state functional MRI in depression unmasks increased connectivity between networks via the dorsal nexus

    Yvette I. Sheline;Joseph L. Price;Zhizi Yan;Mark A. Mintun

  • Brain blood flow measured with intravenous H2(15)O. II. Implementation and validation.

    M. E. Raichle;W. R. W. Martin;P. Herscovitch;M. A. Mintun

  • Use of Florbetapir-PET for Imaging β-Amyloid Pathology

    Christopher M. Clark;Julie A. Schneider;Barry J. Bedell;Thomas G. Beach

  • [11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease.

    M. A. Mintun;G. N. LaRossa;Y. I. Sheline;C. S. Dence

  • Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

    Y. Iturria-Medina;R. C. Sotero;P. J. Toussaint;J. M. Mateos-Pérez

  • A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography.

    Mark A. Mintun;Marcus E. Raichle;Michael R. Kilbourn;G. Frederick Wooten

  • Cerebrospinal Fluid tau/β-Amyloid42 Ratio as a Prediction of Cognitive Decline in Nondemented Older Adults

    Anne M. Fagan;Catherine M. Roe;Chengjie Xiong;Mark A. Mintun

  • APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging

    John C. Morris;Catherine M. Roe;Chengjie Xiong;Anne M. Fagan

Frequent Co-Authors

John C. Morris
John C. Morris Washington University in St. Louis
Michael J. Pontecorvo
Michael J. Pontecorvo Eli Lilly (United States)
Michael D. Devous
Michael D. Devous Avid Radiopharmaceuticals
Marcus E. Raichle
Marcus E. Raichle Washington University in St. Louis
Yvette I. Sheline
Yvette I. Sheline University of Pennsylvania
Adam S. Fleisher
Adam S. Fleisher Avid Radiopharmaceuticals
Marwan N. Sabbagh
Marwan N. Sabbagh Lou Ruvo Brain Institute
David M. Holtzman
David M. Holtzman Washington University in St. Louis
Anne M. Fagan
Anne M. Fagan Washington University in St. Louis
Eric M. Reiman
Eric M. Reiman Arizona State University

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