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Manfred Westphal

Manfred Westphal

D-Index & Metrics

Medicine

D-Index
97
Citations
42990
World Ranking
9145
National Ranking
510

Overview

Manfred Westphal is affiliated with Universität Hamburg in Germany and has a significant body of work in the field of Medicine, with a focus on Neurology, Genetics, Pulmonary and Respiratory Medicine, Surgery, and Molecular Biology.

Their research covers key topics including:

  • Glioma Diagnosis and Treatment
  • Brain Metastases and Treatment
  • Meningioma and schwannoma management
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Extracellular vesicles in disease
  • Intracranial Aneurysms: Treatment and Complications
  • Cancer Immunotherapy and Biomarkers

Westphal has published extensively in several frequent venues, particularly:

  • Neuro-Oncology
  • Brain and Spine
  • Acta Neuropathologica
  • Neuro-Oncology Advances
  • Neurosurgical Review

Their frequent collaborators include:

  • Katrin Lamszus
  • Franz Ricklefs
  • Malte Mohme
  • Lasse Dührsen
  • Cécile L. Maire

Some notable recent publications authored or co-authored by Westphal include:

  • EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood, 2020, Nature Reviews Clinical Oncology
  • CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas, 2020, Acta Neuropathologica
  • Integrated Molecular-Morphologic Meningioma Classification: A Multicenter Retrospective Analysis, Retrospectively and Prospectively Validated, 2021, Zurich Open Repository and Archive (University of Zurich)
  • Genome-wide methylation profiling of glioblastoma cell-derived extracellular vesicle DNA allows tumor classification, 2021, Neuro-Oncology
  • Effectiveness of Lumbar Cerebrospinal Fluid Drain Among Patients With Aneurysmal Subarachnoid Hemorrhage, 2023, JAMA Neurology

Best Publications

  • DNA methylation-based classification of central nervous system tumours

    David Capper;David Capper;David Capper;David T. W. Jones;Martin Sill;Volker Hovestadt

  • A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma.

    Manfred Westphal;Dana C. Hilt;Enoch Bortey;Patrick Delavault

  • Cost of Migration: Invasion of Malignant Gliomas and Implications for Treatment

    A. Giese;R. Bjerkvig;M.E. Berens;M. Westphal

  • EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood.

    Michael Weller;Martin van den Bent;Matthias Preusser;Emilie Le Rhun

  • Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: Implications for classification of gliomas

    Christian Hartmann;Christian Hartmann;Bettina Hentschel;Wolfgang Wick;Wolfgang Wick;David Capper

  • European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas

    Michael Weller;Martin van den Bent;Jörg C Tonn;Roger Stupp

  • NovoTTF-100A versus physician’s choice chemotherapy in recurrent glioblastoma: A randomised phase III trial of a novel treatment modality

    Roger Stupp;Eric T. Wong;Andrew A. Kanner;David Steinberg

  • Glioma invasion in the central nervous system.

    A Giese;M Westphal

  • DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis

    Felix Sahm;Felix Sahm;Daniel Schrimpf;Damian Stichel;David T.W. Jones

  • Molecular Predictors of Progression-Free and Overall Survival in Patients With Newly Diagnosed Glioblastoma: A Prospective Translational Study of the German Glioma Network

    Michael Weller;Jörg Felsberg;Christian Hartmann;Hilmar Berger

  • A hierarchy of self-renewing tumor-initiating cell types in glioblastoma

    Ruihuan Chen;Merry C. Nishimura;Stephanie M. Bumbaca;Samir Kharbanda

  • Inhibition of glioma angiogenesis and growth in vivo by systemic treatment with a monoclonal antibody against vascular endothelial growth factor receptor-2.

    Philip Kunkel;Ulrike Ulbricht;Peter Bohlen;Marc A. Brockmann

  • Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria

    H S Günther;N O Schmidt;H S Phillips;D Kemming

  • Gliadel wafer in initial surgery for malignant glioma: long-term follow-up of a multicenter controlled trial.

    M Westphal;Z Ram;V Riddle;D Hilt

  • Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles

    Franz L. Ricklefs;Franz L. Ricklefs;Quazim Alayo;Harald Krenzlin;Ahmad B. Mahmoud;Ahmad B. Mahmoud

  • Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma.

    Sandeep Kunwar;Susan Chang;Manfred Westphal;Michael Vogelbaum

  • Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.

    Albert Lai;Samir Kharbanda;Whitney B. Pope;Anh Tran

  • First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma.

    Linda M. Liau;Keyoumars Ashkan;David D. Tran;Jian L. Campian

  • A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo.

    Tobias Martens;Nils-Ole Schmidt;Carmen Eckerich;Regina Fillbrandt

  • Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angiogenesis

    Nils Ole Schmidt;Manfred Westphal;Christian Hagel;Süleyman Ergün

Frequent Co-Authors

Michael Weller
Michael Weller University of Zurich
Guido Reifenberger
Guido Reifenberger Heinrich Heine University Düsseldorf
Andreas von Deimling
Andreas von Deimling Heidelberg University
Wolfgang Wick
Wolfgang Wick German Cancer Research Center
Torsten Pietsch
Torsten Pietsch University of Bonn
Andreas K. Engel
Andreas K. Engel Universität Hamburg
Felix Sahm
Felix Sahm University Hospital Heidelberg
Christian Gerloff
Christian Gerloff University Medical Center Hamburg-Eppendorf
Markus Loeffler
Markus Loeffler Leipzig University
Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center

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