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Immunology

D-Index
60
Citations
16293
World Ranking
3296
National Ranking
1533

Overview

Laura P. Hale is affiliated with Duke University in the United States and conducts research primarily in the fields of Immunology and Microbiology as well as Medicine. Their work spans several subfields, including Immunology, Molecular Biology, Endocrine and Autonomic Systems, Surgery, and Epidemiology.

The scientist's research topics encompass:

  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Circadian rhythm and melatonin
  • Single-cell and spatial transcriptomics
  • Immunotherapy and Immune Responses
  • Adrenal Hormones and Disorders
  • Inflammatory Bowel Disease

Laura P. Hale has published multiple papers in journals such as PLoS ONE, Frontiers in Immunology, Nature Immunology, Nature Biomedical Engineering, the International Journal of Obesity, and bioRxiv (Cold Spring Harbor Laboratory). Recent publications include:

  • "Age-Related Changes in Thymic Central Tolerance" (2021, Frontiers in Immunology)
  • "Age-related epithelial defects limit thymic function and regeneration" (2024, Nature Immunology)
  • "Targeting T-cell oxidative metabolism to improve influenza survival in a mouse model of obesity" (2020, International Journal of Obesity)
  • "Engaging natural antibody responses for the treatment of inflammatory bowel disease via phosphorylcholine-presenting nanofibres" (2023, Nature Biomedical Engineering)
  • "Histopathologic assessment of cultured human thymus" (2020, PLoS ONE)

Frequent collaborators in their research include Andrew N. Macintyre, Jayashree Srinivasan, Lauren I. R. Ehrlich, Ellen R. Richie, and Nancy R. Manley, with whom multiple publications have been produced.

Throughout their career, Laura P. Hale has contributed to research published predominantly in these venues:

  • PLoS ONE
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Data Repository, Duke University
  • Frontiers in Immunology
  • Nature Immunology

Best Publications

  • Spatial organization and composition of the mucosal flora in patients with inflammatory bowel disease.

    Alexander Swidsinski;Jutta Weber;Vera Loening-Baucke;Laura P. Hale

  • The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function.

    Andrew N. Macintyre;Valerie A. Gerriets;Amanda G. Nichols;Ryan D. Michalek

  • CD44 — A molecule involved in leukocyte adherence and T-cell activation

    Barton F. Haynes;Marilyn J. Telen;Laura P. Hale;Stephen M. Denning

  • Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation

    Valerie A. Gerriets;Rigel J. Kishton;Amanda G. Nichols;Andrew N. Macintyre

  • The Role of the Thymus in Immune Reconstitution in Aging, Bone Marrow Transplantation, and HIV-1 Infection

    Haynes Bf;Markert Ml;Sempowski Gd;Patel Dd

  • Bone Marrow–generated Dendritic Cells Pulsed with Tumor Extracts or Tumor RNA Induce Antitumor Immunity against Central Nervous System Tumors

    David M. Ashley;Brenda Faiola;Smita Nair;Laura P. Hale

  • Monoclonal Antibodies against EGFRvIII Are Tumor Specific and React with Breast and Lung Carcinomas and Malignant Gliomas

    Carol J. Wikstrand;Laura P. Hale;Surinder K. Batra;M. Leslie Hill

  • Adherent Biofilms in Bacterial Vaginosis

    Alexander Swidsinski;Werner Mendling;Vera Loening-Baucke;Axel Ladhoff

  • Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2

    Pengnian Lin;Jake A. Buxton;Ann Acheson;Czeslaw Radziejewski

  • Leukemia Inhibitory Factor, Oncostatin M, IL-6, and Stem Cell Factor mRNA Expression in Human Thymus Increases with Age and Is Associated with Thymic Atrophy

    Gregory D. Sempowski;Laura P. Hale;John S. Sundy;Janice M. Massey

  • Transplantation of Thymus Tissue in Complete DiGeorge Syndrome

    M L Markert;A Boeck;L P Hale;A L Kloster

  • Analysis of the human thymic perivascular space during aging.

    Kristina G. Flores;Jie Li;Gregory D. Sempowski;Barton F. Haynes

  • Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates CD8+ cell-mediated immunity against tumors located in the "immunologically privileged" central nervous system

    John H. Sampson;Gerald E. Archer;David M. Ashley;Herbert E. Fuchs

  • Proteinase activity and stability of natural bromelain preparations

    Laura P. Hale;Paula K. Greer;Chau T. Trinh;Cindy L. James

  • Measurement of an adhesion molecule as an indicator of inflammatory disease activity: Up‐regulation of the receptor for hyaluronate (CD44) in rheumatoid arthritis

    Barton F. Haynes;Laura P. Hale;Karen L. Patton;Margaret E. Martin

  • Immunohistologic analysis of the distribution of cell adhesion molecules within the inflammatory synovial microenvironment

    Laura P. Hale;Margaret E. Martin;Donald E. McCollum;James A. Nunley

  • Unarmed, tumor-specific monoclonal antibody effectively treats brain tumors.

    John H. Sampson;Laura E. Crotty;Samson Lee;Gary E. Archer

  • Analysis of the adult thymus in reconstitution of T lymphocytes in HIV-1 infection

    Barton F. Haynes;Laura P. Hale;Kent J. Weinhold;Dhavalkumar D. Patel

  • Review of 54 patients with complete DiGeorge anomaly enrolled in protocols for thymus transplantation: outcome of 44 consecutive transplants

    M. Louise Markert;Blythe H. Devlin;Marilyn J. Alexieff;Jie Li

  • A mouse model for hereditary hemorrhagic telangiectasia (HHT) type 2

    Sudha Srinivasan;Martha A. Hanes;Tayeashai Dickens;Mary E. M. Porteous

Frequent Co-Authors

Barton F. Haynes
Barton F. Haynes Duke University
Gregory D. Sempowski
Gregory D. Sempowski Duke University
Dhavalkumar D. Patel
Dhavalkumar D. Patel University of North Carolina at Chapel Hill
Darell D. Bigner
Darell D. Bigner Duke University
John H. Sampson
John H. Sampson Duke University
Michael A. Skinner
Michael A. Skinner Imperial College London
Rebecca H. Buckley
Rebecca H. Buckley Duke University
John Bartlett
John Bartlett Duke University
Kent J. Weinhold
Kent J. Weinhold Duke University
Gary E. Archer
Gary E. Archer Duke University

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Related Online Degrees & Career Pathways

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