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Neuroscience

D-Index
75
Citations
17715
World Ranking
2042
National Ranking
185

Overview

Ullrich Wüllner is affiliated with the University Hospital Bonn in Germany and has contributed extensively to medical research, particularly within the fields of medicine and neuroscience. Their work is notably concentrated in neurology and cellular and molecular neuroscience, with a significant focus on Parkinson's disease and related neurological disorders.

The scientist has a research portfolio that prominently features topics such as:

  • Parkinson's Disease Mechanisms and Treatments
  • Neurological disorders and treatments
  • Genetic Neurodegenerative Diseases
  • Advanced MRI Techniques and Applications
  • Advanced Neuroimaging Techniques and Applications
  • Neurological diseases and metabolism
  • Genetics and Neurodevelopmental Disorders

Ullrich Wüllner has published research in several key journals, frequently appearing in the following publication venues:

  • Movement Disorders
  • Parkinsonism & Related Disorders
  • Journal of Neural Transmission
  • Scientific Reports
  • International Journal of Molecular Sciences

Among their recent papers are:

  • "Systematic analysis of gut microbiome reveals the role of bacterial folate and homocysteine metabolism in Parkinson's disease" (2021, Cell Reports)
  • "Advanced glycation end products and protein carbonyl levels in plasma reveal sex-specific differences in Parkinson's and Alzheimer's disease" (2020, Redox Biology)
  • "The heterogeneity of Parkinson's disease" (2023, Journal of Neural Transmission)
  • "Much ado about nothing? Off-target amplification can lead to false-positive bacterial brain microbiome detection in healthy and Parkinson's disease individuals" (2021, Microbiome)
  • "The patients' perspective on the burden of idiopathic intracranial hypertension" (2021, The Journal of Headache and Pain)

Their collaborations include frequent coauthors such as:

  • Veronika Purrer
  • Henning Boecker
  • Valeri Borger
  • Neeraj Upadhyay
  • Frederic Carsten Schmeel

The scientist's focus on molecular biology and genetics supports their research approach in neurodegenerative diseases and neuroimaging techniques. Their extensive publication record in highly regarded journals reflects a sustained engagement with advancing the understanding of neurological disorders, especially Parkinson's disease.

Best Publications

  • PGC-1α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease

    Bin Zheng;Zhixiang Liao;Joseph J. Locascio;Kristen A. Lesniak

  • Rapamycin alleviates toxicity of different aggregate-prone proteins.

    Zdenek Berger;Brinda Ravikumar;Fiona M. Menzies;Lourdes Garcia Oroz

  • Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naïve Parkinson’s disease patients

    Janis R. Bedarf;Falk Hildebrand;Luis P. Coelho;Shinichi Sunagawa;Shinichi Sunagawa

  • Elevated cerebrospinal fluid and blood concentrations of oxytocin following its intranasal administration in humans

    Nadine Striepens;Keith M. Kendrick;Vanessa Hanking;Rainer Landgraf

  • Methylation Regulates Alpha-Synuclein Expression and Is Decreased in Parkinson's Disease Patients' Brains

    Ahmad Jowaed;Ina Schmitt;Oliver Kaut;Ullrich Wüllner

  • Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease.

    Philipp Koch;Peter Breuer;Michael Peitz;Johannes Jungverdorben

  • Sleep attacks, daytime sleepiness, and dopamine agonists in Parkinson's disease.

    Sebastian Paus;Hans Michael Brecht;Jürgen Köster;Gert Seeger

  • SNCA Variants Are Associated with Increased Risk for Multiple System Atrophy

    Sonja W. Scholz;Sonja W. Scholz;Henry Houlden;Claudia Schulte;Manu Sharma

  • Multiple regions of alpha-synuclein are associated with Parkinson's disease.

    Jakob C. Mueller;Julia Fuchs;Anne Hofer;Alexander Zimprich

  • Extracellular phosphorylation of the amyloid β-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease

    Sathish Kumar;Nasrollah Rezaei-Ghaleh;Dick Terwel;Dietmar R Thal

  • Induction of Nitric Oxide Synthase and Nitric Oxide‐Mediated Apoptosis in Neuronal PC12 Cells After Stimulation with Tumor Necrosis FActor‐α/Lipopolysaccharide

    Michael T. Heneka;Peter‐A. Löschmann;Marc Gleichmann;Michael Weller

  • Glutathione depletion and neuronal cell death: the role of reactive oxygen intermediates and mitochondrial function.

    U. Wüllner;J. Seyfried;P. Groscurth;S. Beinroth

  • Glutathione depletion potentiates Mptp and Mpp+ toxicity in nigral dopaminergic neurones

    Ullrich Wüllner;Peter-andreas Löschmann;Jörg B. Schulz;Annette Schmid

  • Qigong exercise for the symptoms of parkinson's disease : A randomized, controlled pilot study

    Tanya Schmitz-Hübsch;Derek Pyfer;Karin Kielwein;Rolf Fimmers

  • An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis

    Annett Boeddrich;Sébastien Gaumer;Annette Haacke;Nikolay Tzvetkov

  • Prion-like propagation of human brain-derived alpha-synuclein in transgenic mice expressing human wild-type alpha-synuclein.

    Maria E. Bernis;Julius T. Babila;Sara Breid;Katharina Annick Wüsten

  • Bright light therapy in Parkinson's disease: A pilot study

    Sebastian Paus;Tanja Schmitz-Hübsch;Ullrich Wüllner;Antje Vogel

  • Ataxin-3 Represses Transcription via Chromatin Binding, Interaction with Histone Deacetylase 3, and Histone Deacetylation

    Bernd O. Evert;Julieta Araujo;Ana M. Vieira-Saecker;Rob A. I. de Vos

  • Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine-induced apoptotic cell death by inhibition of inducible nitric oxide synthase.

    Michael T Heneka;Michael T Heneka;Douglas L. Feinstein;Elena Galea;Marc Gleichmann

  • Structural and functional analysis of ataxin-2 and ataxin-3.

    Mario Albrecht;Michael Golatta;Ullrich Wüllner;Thomas Lengauer

  • Neuropsychological Features of Patients with Spinocerebellar Ataxia (SCA) Types 1, 2, 3, and 6

    Ina Klinke;Martina Minnerop;Martina Minnerop;Tanja Schmitz-Hübsch;Marc Hendriks

  • Inflammatory genes are upregulated in expanded ataxin-3-expressing cell lines and spinocerebellar ataxia type 3 brains

    Bernd O. Evert;Ina R. Vogt;Claudia Kindermann;Lucia Ozimek

Frequent Co-Authors

Thomas Klockgether
Thomas Klockgether German Center for Neurodegenerative Diseases
Daniela Berg
Daniela Berg University Hospital Schleswig-Holstein
Nicholas W. Wood
Nicholas W. Wood University College London
René Hurlemann
René Hurlemann Carl von Ossietzky University of Oldenburg
Christine Klein
Christine Klein University of Lübeck
Christoph Helmstaedter
Christoph Helmstaedter University Hospital Bonn
Katrin Amunts
Katrin Amunts Forschungszentrum Jülich
Claudia Trenkwalder
Claudia Trenkwalder University of Göttingen
Karsten Witt
Karsten Witt Kiel University

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