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Kristian Pietras

Kristian Pietras

D-Index & Metrics

Molecular Biology

D-Index
54
Citations
19507
World Ranking
2298
National Ranking
32

Overview

Kristian Pietras is affiliated with Lund University in Sweden and has a diverse research portfolio primarily in Medicine and Biochemistry, Genetics and Molecular Biology. Their scholarly work focuses on oncology and immunology, with significant contributions to cancer research and molecular biology.

The scientist's research subfields include:

  • Oncology
  • Immunology
  • Cancer Research
  • Molecular Biology
  • Pulmonary and Respiratory Medicine

Kristian Pietras's main research topics cover:

  • Cancer Immunotherapy and Biomarkers
  • Cancer Cells and Metastasis
  • Cancer, Hypoxia, and Metabolism
  • Immune cells in cancer
  • Ferroptosis and cancer prognosis
  • Immunotherapy and Immune Responses
  • Immune Cell Function and Interaction

The scientist has published extensively in several journals, with frequent publications in:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuro-Oncology
  • Nature
  • Nature Cell Biology

Among recent papers, notable works include:

  • "Tertiary lymphoid structures improve immunotherapy and survival in melanoma," 2020, Nature
  • "Heterogeneity of cancer-associated fibroblasts: Opportunities for precision medicine," 2020, Cancer Science
  • "RETRACTED ARTICLE: CCM3 is a gatekeeper in focal adhesions regulating mechanotransduction and YAP/TAZ signalling," 2021, Nature Cell Biology
  • "Infection of Brain Pericytes Underlying Neuropathology of COVID-19 Patients," 2021, International Journal of Molecular Sciences
  • "Author Correction: Tertiary lymphoid structures improve immunotherapy and survival in melanoma," 2020, Nature

Frequent co-authors collaborating with Kristian Pietras include:

  • Jonas Sjölund
  • Matteo Bocci
  • Eugenia Cordero
  • Göran Jönsson
  • Paulina Bolívar

Best Publications

  • Protein detection using proximity-dependent DNA ligation assays

    Simon Fredriksson;Mats Gullberg;Jonas Jarvius;Charlotta Olsson

  • Hallmarks of cancer: interactions with the tumor stroma.

    Kristian Pietras;Arne Östman

  • PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor.

    Erika Bergsten;Marko Uutela;Xuri Li;Kristian Pietras

  • A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition.

    Theresa Vincent;Theresa Vincent;Etienne P. A. Neve;Etienne P. A. Neve;Jill R. Johnson;Alexander Kukalev

  • Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing

    Michael Bartoschek;Nikolay Oskolkov;Matteo Bocci;John Lövrot

  • Consensus guidelines for the use and interpretation of angiogenesis assays

    Patrycja Nowak-Sliwinska;Kari Alitalo;Elizabeth Allen;Andrey Anisimov

  • Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors.

    Kristian Pietras;Arne Östman;Mats Sjöquist;Elisabeth Buchdunger

  • PDGF receptors as cancer drug targets

    Kristian Pietras;Tobias Sjöblom;Kristofer Rubin;Carl-Henrik Heldin

  • Vascular endothelial growth factor B controls endothelial fatty acid uptake

    Carolina E. Hagberg;Annelie Falkevall;Annelie Falkevall;Xun Wang;Xun Wang;Erik Larsson

  • Inhibition of PDGF Receptor Signaling in Tumor Stroma Enhances Antitumor Effect of Chemotherapy

    Kristian Pietras;Kristofer Rubin;Tobias Sjöblom;Elisabeth Buchdunger

  • Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke

    Enming J Su;Linda Fredriksson;Melissa Geyer;Erika Folestad

  • Functions of Paracrine PDGF Signaling in the Proangiogenic Tumor Stroma Revealed by Pharmacological Targeting

    Kristian Pietras;Jessica C. Pahler;Gabriele Bergers;Douglas Hanahan

  • The dermatofibrosarcoma protuberans-associated collagen type Ialpha1/platelet-derived growth factor (PDGF) B-chain fusion gene generates a transforming protein that is processed to functional PDGF-BB.

    A Shimizu;K P O'Brien;T Sjöblom;K Pietras

  • Growth inhibition of dermatofibrosarcoma protuberans tumors by the platelet-derived growth factor receptor antagonist STI571 through induction of apoptosis.

    Tobias Sjöblom;Akira Shimizu;Kevin P. O’Brien;Kristian Pietras

  • Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression

    Marcela Franco;Pernilla Roswall;Eliane Cortez;Douglas Hanahan;Douglas Hanahan

  • Angiogenesis stimulated by PDGF-CC, a novel member in the PDGF family, involves activation of PDGFR-alphaalpha and -alphabeta receptors.

    Renhai Cao;Ebba Bråkenhielm;Xuri Li;Kristian Pietras

  • Paracrine Signaling by Platelet-Derived Growth Factor-CC Promotes Tumor Growth by Recruitment of Cancer-Associated Fibroblasts

    Charlotte Anderberg;Hong Li;Linda Fredriksson;Johanna Andrae

  • ALK1 as an emerging target for antiangiogenic therapy of cancer

    Sara I. Cunha;Kristian Pietras

  • Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis

    Sara I. Cunha;Evangelia Pardali;Midory Thorikay;Charlotte Anderberg

  • Platelet-Derived Growth Factor D Induces Cardiac Fibrosis and Proliferation of Vascular Smooth Muscle Cells in Heart-Specific Transgenic Mice

    Annica Pontén;Erika Bergsten Folestad;Kristian Pietras;Ulf Eriksson

Frequent Co-Authors

Arne Östman
Arne Östman Karolinska Institute
Carl-Henrik Heldin
Carl-Henrik Heldin Uppsala University
Ulf Eriksson
Ulf Eriksson AstraZeneca (United Kingdom)
Karin Jirström
Karin Jirström Lund University
Kristofer Rubin
Kristofer Rubin Uppsala University
Christer Betsholtz
Christer Betsholtz Uppsala University
Lars Rönnstrand
Lars Rönnstrand Lund University
Anna M. Blom
Anna M. Blom Lund University
Jan Mulder
Jan Mulder Karolinska Institute
Jonas Bergh
Jonas Bergh Karolinska Institute

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