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Molecular Biology

D-Index
43
Citations
7232
World Ranking
2977
National Ranking
18

Overview

Kanaga Sabapathy is affiliated with the National University of Singapore in Singapore. Their research spans multiple disciplines, primarily within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine.

Their scientific contributions focus mainly on molecular biology and cancer-related topics, with specific attention to oncology, cancer research, and biotechnology. Other areas of study include pulmonary and respiratory medicine. Sabapathy's work also addresses key themes such as cancer-related molecular pathways, cancer research and treatments, cancer genomics and diagnostics, epigenetics and DNA methylation, ferroptosis and cancer prognosis, autophagy in disease and therapy, and the impacts of COVID-19 on healthcare.

Publication venues where Sabapathy has frequently contributed include:

  • Cancer Research
  • Cell Reports
  • Disease Models & Mechanisms
  • Frontiers in Oncology
  • EMBO Reports

Frequent coauthors collaborating with Sabapathy are:

  • Shazib Pervaiz (5 publications)
  • Christian G. Krueger (4 publications)
  • Fanny Xueting Teo (4 publications)
  • David P. Lane (4 publications)
  • Veronique Kiak Mien Tan (3 publications)

Recent papers by Sabapathy include:

  • MOAP-1-mediated dissociation of p62/SQSTM1 bodies releases Keap1 and suppresses Nrf2 signaling, 2021, EMBO Reports
  • Cancer Cells Shuttle Extracellular Vesicles Containing Oncogenic Mutant p53 Proteins to the Tumor Microenvironment, 2021, Cancers
  • p53-Related Transcription Targets of TAp73 in Cancer Cells-Bona Fide or Distorted Reality?, 2020, International Journal of Molecular Sciences
  • An Asian Perspective of the Management of COVID-19: the Asian National Cancer Centers Alliance Led Regional Comparison, 2020, Asian Pacific Journal of Cancer Care
  • An Asian Body to Tackle Cancers in Asia - The Asian National Cancer Centers Alliance, 2020, Asian Pacific Journal of Cancer Prevention

Best Publications

  • Distinct Roles for JNK1 and JNK2 in Regulating JNK Activity and c-Jun-Dependent Cell Proliferation

    Kanaga Sabapathy;Konrad Hochedlinger;Shin Yuen Nam;Anton Bauer

  • Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2.

    Kanaga Sabapathy;Wolfram Jochum;Konrad Hochedlinger;Lufen Chang

  • Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than others

    Kanaga Sabapathy;David P Lane

  • JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development

    Kanaga Sabapathy;Yinling Hu;Tuula Kallunki;Martin Schreiber

  • JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanisms

    Jean-Pierre David;Kanaga Sabapathy;Oskar Hoffmann;Maria H Idarraga

  • C-Jun Nh2-Terminal Kinase (Jnk)1 and Jnk2 Have Similar and Stage-Dependent Roles in Regulating T Cell Apoptosis and Proliferation

    Kanaga Sabapathy;Tuula Kallunki;Jean-Pierre David;Isabella Graef

  • c-Jun promotes cellular survival by suppression of PTEN.

    K. Hettinger;F. Vikhanskaya;M. K. Poh;M. K. Lee

  • An Apoptotic Signaling Pathway in the Interferon Antiviral Response Mediated by RNase L and c-Jun NH2-terminal Kinase

    Geqiang Li;Geqiang Li;Ying Xiang;Kanaga Sabapathy;Robert H. Silverman

  • Functional crosstalk between type I and II interferon through the regulated expression of STAT1.

    Daniel J Gough;Daniel J Gough;Daniel J Gough;Nicole L Messina;Nicole L Messina;Linda Hii;Linda Hii;Jodee Ann Gould

  • Regulation of ES cell differentiation by functional and conformational modulation of p53.

    Kanaga Sabapathy;Martina Klemm;Rudolf Jaenisch;Erwin F. Wagner

  • Role of the JNK pathway in human diseases

    Kanaga Sabapathy

  • Cancer-derived p53 mutants suppress p53-target gene expression—potential mechanism for gain of function of mutant p53

    Faina Vikhanskaya;Ming Kei Lee;Marco Mazzoletti;Massimo Broggini

  • Trp53-dependent DNA-repair is affected by the codon 72 polymorphism

    M Siddique;K Sabapathy

  • Differential effects of JNK1 and JNK2 on signal specific induction of apoptosis

    Konrad Hochedlinger;Konrad Hochedlinger;Erwin F Wagner;Kanaga Sabapathy

  • Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors.

    Mi Ni Huang;Willie Yu;Wei Wei Teoh;Maude Ardin

  • JNK2: A Negative Regulator of Cellular Proliferation

    Kanaga Sabapathy;Erwin F Wagner

  • Cell-type, Dose, and Mutation-type Specificity Dictate Mutant p53 Functions In Vivo

    Ming Kei Lee;Wei Wei Teoh;Beng Hooi Phang;Wei Min Tong

  • Jun N-terminal kinase 2 modulates thymocyte apoptosis and T cell activation through c-Jun and nuclear factor of activated T cell (NF-AT)

    Axel Behrens;Kanaga Sabapathy;Isabella Graef;Mike Cleary

  • ERK Phosphorylates p66shcA on Ser36 and Subsequently Regulates p27kip1 Expression via the Akt-FOXO3a Pathway: Implication of p27kip1 in Cell Response to Oxidative Stress

    Yuanyu Hu;Xueying Wang;Li Zeng;De-Yu Cai

  • c-Jun Regulates the Stability and Activity of the p53 Homologue, p73 *

    Wen Hong Toh;M. M. Siddique;Lakshmanane Boominathan;Kai Wei Lin

Frequent Co-Authors

Erwin F. Wagner
Erwin F. Wagner Medical University of Vienna
Joseph A. Trapani
Joseph A. Trapani Peter MacCallum Cancer Centre
David P. Lane
David P. Lane Karolinska Institute
Ricky W. Johnstone
Ricky W. Johnstone Peter MacCallum Cancer Centre
Michael Karin
Michael Karin University of California, San Diego
Konrad Hochedlinger
Konrad Hochedlinger Harvard University
Patrick Tan
Patrick Tan Duke NUS Graduate Medical School
Jiri Zavadil
Jiri Zavadil International Agency For Research On Cancer
Zhi-Cheng Xiao
Zhi-Cheng Xiao Monash University
Monica Hollstein
Monica Hollstein University of Leeds

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