What is she best known for?
The fields of study she is best known for:
- Enzyme
- Signal transduction
- Biochemistry
Irit Lax mainly investigates Cell biology, Receptor, Platelet-derived growth factor receptor, Receptor tyrosine kinase and Tyrosine phosphorylation.
Her research integrates issues of Fibroblast growth factor receptor and Fibroblast growth factor in her study of Cell biology.
Her Receptor research is included under the broader classification of Biochemistry.
Irit Lax has included themes like Protein kinase A, Mitogen-activated protein kinase kinase, Tropomyosin receptor kinase C, Proto-oncogene tyrosine-protein kinase Src and MAP2K7 in her Receptor tyrosine kinase study.
Irit Lax has researched Tyrosine phosphorylation in several fields, including GRB2 and Protein tyrosine phosphatase.
The various areas that Irit Lax examines in her Epidermal growth factor study include Epidermoid carcinoma, Cancer research and Immunology.
Her most cited work include:
- Cellular signaling by fibroblast growth factor receptors. (1535 citations)
- Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin (1334 citations)
- A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway (741 citations)
What are the main themes of her work throughout her whole career to date?
Her primary scientific interests are in Cell biology, Receptor, Molecular biology, Receptor tyrosine kinase and Epidermal growth factor.
Her Cell biology research is multidisciplinary, relying on both Fibroblast growth factor receptor and Fibroblast growth factor.
Her Receptor study combines topics from a wide range of disciplines, such as Extracellular, Biophysics and Binding site.
Her work in Molecular biology addresses subjects such as Ligand, which are connected to disciplines such as Stereochemistry.
Her work carried out in the field of Receptor tyrosine kinase brings together such families of science as Tyrosine kinase, Proto-oncogene tyrosine-protein kinase Src and Platelet-derived growth factor receptor.
Irit Lax interconnects Cell surface receptor and Growth factor receptor in the investigation of issues within Epidermal growth factor.
She most often published in these fields:
- Cell biology (56.32%)
- Receptor (41.38%)
- Molecular biology (34.48%)
What were the highlights of her more recent work (between 2010-2020)?
- Receptor tyrosine kinase (31.03%)
- Cell biology (56.32%)
- Receptor (41.38%)
In recent papers she was focusing on the following fields of study:
Irit Lax focuses on Receptor tyrosine kinase, Cell biology, Receptor, Cell signaling and Phosphorylation.
Irit Lax combines subjects such as Tyrosine kinase, Antibody and Molecular biology with her study of Receptor tyrosine kinase.
Her Tyrosine kinase research is multidisciplinary, relying on both Cancer research and Proto-Oncogene Proteins c-kit.
Her work in Cell biology tackles topics such as Fibroblast growth factor receptor which are related to areas like Binding site.
Receptor and Signal transduction are commonly linked in her work.
The Cell signaling study combines topics in areas such as Epidermal growth factor, GTPase, Protein kinase B, Ligand and Structural biology.
Between 2010 and 2020, her most popular works were:
- Differential TAM receptor–ligand–phospholipid interactions delimit differential TAM bioactivities (139 citations)
- Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane (118 citations)
- Structures of beta-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling. (84 citations)
In her most recent research, the most cited papers focused on:
- Enzyme
- Signal transduction
- Amino acid
Her primary areas of investigation include Cell biology, Receptor, Receptor tyrosine kinase, Receptor Protein-Tyrosine Kinases and Cell signaling.
Her Cell biology study combines topics in areas such as Cell surface receptor, Endocytosis and Fibroblast growth factor.
Her research integrates issues of Molecular biology, Phosphorylation and Ligand in her study of Cell surface receptor.
Her Endocytosis study incorporates themes from Protein kinase B and GTPase.
Her Fibroblast growth factor research focuses on Fibroblast growth factor receptor in particular.
As part of her studies on Clathrin, Irit Lax often connects relevant areas like Epidermal growth factor.
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