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Hannele Ruohola-Baker

Hannele Ruohola-Baker

D-Index & Metrics

Molecular Biology

D-Index
57
Citations
13317
World Ranking
2141
National Ranking
1064

Overview

Hannele Ruohola-Baker is affiliated with the University of Washington in the United States. Their research spans multiple fields within biochemistry, genetics, and molecular biology, contributing extensively to the understanding of molecular biology and genetics, along with intersections in medicine.

The scientist's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broad areas, they have focused on several subfields such as:

  • Molecular Biology
  • Genetics
  • Radiology, Nuclear Medicine and Imaging
  • Surgery
  • Ecology

The topics covered in their work include:

  • Monoclonal and Polyclonal Antibodies Research
  • Epigenetics and DNA Methylation
  • Pluripotent Stem Cells Research
  • Dental development and anomalies
  • CRISPR and Genetic Engineering
  • Bacteriophages and microbial interactions
  • Bone and Dental Protein Studies

Hannele Ruohola-Baker has contributed to numerous publications across high-impact venues. Frequent publication platforms for their work are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Nature Communications
  • Frontiers in Dental Medicine
  • Science

Notable recent papers authored by or with involvement of Ruohola-Baker are:

  • "Design of protein-binding proteins from the target structure alone," 2022, Nature
  • "Designed proteins assemble antibodies into modular nanocages," 2021, Science
  • "Design of biologically active binary protein 2D materials," 2021, Nature
  • "Metabolic Control over mTOR-Dependent Diapause-like State," 2020, Developmental Cell
  • "Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice," 2022, Science Translational Medicine

Their frequent coauthors include:

  • David Baker
  • Julie Mathieu
  • Yan Ting Zhao
  • Devon Duron Ehnes
  • Ashish Phal

Best Publications

  • Stem cell division is regulated by the microRNA pathway.

    S. D. Hatfield;H. R. Shcherbata;K. A. Fischer;K. Nakahara

  • HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC‐to‐EpiSC/hESC transition

    Wenyu Zhou;Michael Choi;Daciana Margineantu;Lilyana Margaretha

  • HIF Induces Human Embryonic Stem Cell Markers in Cancer Cells

    Julie Mathieu;Zhan Zhang;Wenyu Zhou;Amy J. Wang

  • Derivation of naive human embryonic stem cells.

    Carol B. Ware;Angelique M. Nelson;Brigham Mecham;Jennifer Hesson

  • Tri-iodo-L-thyronine Promotes the Maturation of Human Cardiomyocytes-Derived from Induced Pluripotent Stem Cells

    Xiulan Yang;Marita Rodriguez;Lil Pabon;Karin A. Fischer

  • The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition

    Henrik Sperber;Julie Mathieu;Yuliang Wang;Amy Ferreccio

  • MicroRNA Discovery and Profiling in Human Embryonic Stem Cells by Deep Sequencing of Small RNA Libraries

    Merav Bar;Stacia K. Wyman;Brian R. Fritz;Junlin Qi

  • Transient posterior localization of a kinesin fusion protein reflects anteroposterior polarity of the Drosophila oocyte

    Ira Clark;Edward Giniger;Hannele Ruohola-Baker;Lily Yeh Jan

  • Maelstrom, a Drosophila spindle-class gene, encodes a protein that colocalizes with Vasa and RDE1/AGO1 homolog, Aubergine, in nuage.

    Seth D. Findley;Mio Tamanaha;Nigel J. Clegg;Hannele Ruohola-Baker

  • Notch-Delta signaling induces a transition from mitotic cell cycle to endocycle in Drosophila follicle cells

    Wu-Min Deng;Cassandra Althauser;Hannele Ruohola-Baker

  • Let-7 family of microRNA is required for maturation and adult-like metabolism in stem cell-derived cardiomyocytes

    Kavitha T. Kuppusamy;Daniel C. Jones;Henrik Sperber;Anup Madan

  • Single-Cell Transcriptomic Analysis of Cardiac Differentiation from Human PSCs Reveals HOPX-Dependent Cardiomyocyte Maturation.

    Clayton E. Friedman;Quan Nguyen;Samuel W. Lukowski;Abbigail Helfer

  • Hypoxia-Inducible Factors Have Distinct and Stage-Specific Roles during Reprogramming of Human Cells to Pluripotency

    Julie Mathieu;Wenyu Zhou;Yalan Xing;Henrik Sperber

  • Fatty Acids Enhance the Maturation of Cardiomyocytes Derived from Human Pluripotent Stem Cells.

    Xiulan Yang;Marita L. Rodriguez;Andrea Leonard;Lihua Sun

  • microRNA and stem cell function

    Steven Hatfield;Hannele Ruohola-Baker

  • Dystroglycan is required for polarizing the epithelial cells and the oocyte in Drosophila.

    Wu Min Deng;Martina Schneider;Richard Frock;Casimiro Castillejo-Lopez

  • microRNAs regulate human embryonic stem cell division.

    Junlin Qi;Jenn Yah Yu;Halyna R. Shcherbata;Julie Mathieu

  • Characterization of microRNAs involved in embryonic stem cell states.

    Bradford Stadler;Irena Ivanovska;Kshama Mehta;Sunny Song

  • Spatially localized rhomboid is required for establishment of the dorsal-ventral axis in Drosophila oogenesis

    Hannele Ruohola-Baker;Ellsworth Grell;Tze Bin Chou;David Baker

  • Metabolic remodeling during the loss and acquisition of pluripotency.

    Julie Mathieu;Hannele Ruohola-Baker

Frequent Co-Authors

David Baker
David Baker University of Washington
Randall T. Moon
Randall T. Moon University of Washington
Charles E. Murry
Charles E. Murry University of Washington
Oliver Fiehn
Oliver Fiehn University of California, Davis
Walter L. Ruzzo
Walter L. Ruzzo University of Washington
James J. De Yoreo
James J. De Yoreo Pacific Northwest National Laboratory
Marshall S. Horwitz
Marshall S. Horwitz University of Washington
Leonidas Stamatatos
Leonidas Stamatatos Fred Hutchinson Cancer Research Center
Daniel Raftery
Daniel Raftery University of Washington
Lily Yeh Jan
Lily Yeh Jan University of California, San Francisco

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