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Immunology

D-Index
48
Citations
11833
World Ranking
4399
National Ranking
1996

Research.com Recognitions

  • 2021 - Distinguished Fellows of the American Association of Immunologists (AAI)

Overview

Brian D. Evavold is affiliated with the University of Utah in the United States. Their primary research contributions focus on immunology and microbiology, with significant work in medicine. Their studies cover several subfields, including immunology, oncology, public health, environmental and occupational health, radiology, nuclear medicine and imaging, and immunology and allergy.

The scientist has contributed extensively to topics including T-cell and B-cell immunology, immune cell function and interaction, CAR-T cell therapy research, immunotherapy and immune responses, monoclonal and polyclonal antibodies research, malaria research and control, and cell adhesion molecules research.

Their recent papers include the following:

  • "Tuning T cell receptor sensitivity through catch bond engineering," 2022, Science
  • "Canonical T cell receptor docking on peptide-MHC is essential for T cell signaling," 2021, Science
  • "The magnitude of LFA-1/ICAM-1 forces fine-tune TCR-triggered T cell activation," 2022, Science Advances
  • "IL-21 from high-affinity CD4 T cells drives differentiation of brain-resident CD8 T cells during persistent viral infection," 2020, Science Immunology
  • "Mechanobiology of T Cell Activation: To Catch a Bond," 2021, Annual Review of Cell and Developmental Biology

Brian D. Evavold has collaborated frequently with other researchers, including Elizabeth Motunrayo Kolawole, Tracey J. Lamb, Douglas H. Cornwall, Baoyu Liu, and Michael A Faust.

Their articles are often published in The Journal of Immunology, with 28 publications in this venue alone. Other frequent publication venues include Science, ImmunoHorizons, bioRxiv (Cold Spring Harbor Laboratory), and Science Advances.

In 2021, Brian D. Evavold was recognized as a Distinguished Fellow of the American Association of Immunologists (AAI).

Best Publications

  • Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells

    Joanne Sloan-Lancaster;Brian D. Evavold;Paul M. Allen

  • Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand

    Brian D. Evavold;Paul M. Allen

  • Accumulation of Dynamic Catch Bonds between TCR and Agonist Peptide-MHC Triggers T Cell Signaling

    Baoyu Liu;Wei Chen;Brian D. Evavold;Cheng Zhu

  • The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness

    Jun Huang;Veronika I. Zarnitsyna;Baoyu Liu;Lindsay J. Edwards

  • Tickling the TCR: selective T-cell functions stimulated by altered peptide ligands

    Brian D. Evavold;Joanne Sloan-Lancaster;Paul M. Allen

  • DO11.10 and OT-II T cells recognize a C-terminal ovalbumin 323-339 epitope

    Jennifer M. Robertson;Peter E. Jensen;Brian D. Evavold

  • Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA- DM

    Dominique A. Weber;Brian D. Evavold;Peter E. Jensen

  • Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity.

    Santhakumar Manicassamy;Rajesh Ravindran;Jiusheng Deng;Herold Oluoch

  • DNA-based nanoparticle tension sensors reveal that T-cell receptors transmit defined pN forces to their antigens for enhanced fidelity

    Yang Liu;Lori Blanchfield;Victor Pui-Yan Ma;Rakieb Andargachew

  • Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding.

    Leah V. Sibener;Ricardo A. Fernandes;Elizabeth M. Kolawole;Catherine B. Carbone

  • Specific T cell recognition of minimally homologous peptides: evidence for multiple endogenous ligands.

    Brian D. Evavold;Joanne Sloan-Lancastert;K.Jeff Wilson;Jonathan B. Rothbard

  • Conserved T Cell Receptor Repertoire in Primary and Memory CD8 T Cell Responses to an Acute Viral Infection

    David J.D. Sourdive;Kaja Murali-Krishna;John D. Altman;Allan J. Zajac

  • Th2 cell clonal anergy as a consequence of partial activation.

    Joanne Sloan-Lancaster;Brian D. Evavold;Paul Allen

  • Separation of T helper 1 clone cytolysis from proliferation and lymphokine production using analog peptides.

    B D Evavold;J Sloan-Lancaster;B L Hsu;P M Allen

  • Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells

    Daniel DiToro;Colleen J. Winstead;Duy Pham;Steven Witte

  • Two-stage cooperative T Cell Receptor-peptide Major Histocompatibility Complex-CD8 trimolecular interactions amplify antigen discrimination

    Ning Jiang;Jun Huang;Lindsay J. Edwards;Baoyu Liu

  • Estimating the Diversity, Completeness, and Cross-Reactivity of the T Cell Repertoire

    Veronika I. Zarnitsyna;Brian D. Evavold;Louis N. Schoettle;Joseph N. Blattman

  • High prevalence of low affinity peptide–MHC II tetramer–negative effectors during polyclonal CD4+ T cell responses

    Joseph J. Sabatino;Jian-Jun Huang;Cheng-Cheng Zhu;Brian D. Evavold

  • Specificity, magnitude, and kinetics of MOG-specific CD8+ T cell responses during experimental autoimmune encephalomyelitis

    Mandy L. Ford;Brian D. Evavold

  • Complete dissection of the Hb(64-76) determinant using T helper 1, T helper 2 clones, and T cell hybridomas.

    B D Evavold;S G Williams;B L Hsu;S Buus

Frequent Co-Authors

Cheng Zhu
Cheng Zhu Georgia Institute of Technology
Mandy L. Ford
Mandy L. Ford Emory University
Paul M. Allen
Paul M. Allen Washington University in St. Louis
Peter E. Jensen
Peter E. Jensen University of Utah
Brian M. Baker
Brian M. Baker University of Notre Dame
Jeremy M. Boss
Jeremy M. Boss Emory University
Christian P. Larsen
Christian P. Larsen Emory University
Gerald T. Nepom
Gerald T. Nepom Virginia Mason Medical Center
Michael I. Nishimura
Michael I. Nishimura Loyola University Chicago
Jamie Rossjohn
Jamie Rossjohn Monash University

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