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D-Index & Metrics

Molecular Biology

D-Index
67
Citations
11244
World Ranking
1592
National Ranking
803

Overview

Peter Rotwein is affiliated with Texas Tech University in the United States and works primarily within the field of Biochemistry, Genetics and Molecular Biology. Their research spans multiple areas, with a concentration on Molecular Biology, Endocrinology, Diabetes and Metabolism, Genetics, Cancer Research, and Cell Biology.

Their recent publications illustrate a focus on molecular and cellular mechanisms, particularly related to growth factors, gene regulation, and RNA biology. Notable papers include:

  • Regulation of gene expression by growth hormone, 2020, Molecular and Cellular Endocrinology
  • Insulin-like growth factors (IGF) in muscle development. Expression of IGF-I, the IGF-I receptor, and an IGF binding protein during myoblast differentiation., 2021, UNC Libraries
  • ZMAT2 in Humans and Other Primates: A Highly Conserved and Understudied Gene, 2020, Evolutionary Bioinformatics
  • Structure and expression of the long noncoding RNA gene MIR503 in humans and non-human primates, 2020, Molecular and Cellular Endocrinology
  • Revisiting the Population Genetics of Human Height, 2020, Journal of the Endocrine Society

The main topics covered by their work include RNA modifications and cancer, RNA research and splicing, epigenetics and DNA methylation, genomics and chromatin dynamics, growth hormone and insulin-like growth factors, single-cell and spatial transcriptomics, as well as FOXO transcription factor regulation.

Frequent co-authors in their research collaborations are:

  • Kabita Baral
  • S E Tollefsen
  • R Lajara
  • R H McCusker
  • David R. Clemmons

Their work has appeared repeatedly in the journal Molecular and Cellular Endocrinology, as well as in Evolutionary Bioinformatics, UNC Libraries, the Journal of the Endocrine Society, and BMC Genomics.

Best Publications

  • Insulin-Like Growth Factors I and II. Peptide, Messenger Ribonucleic Acid and Gene Structures, Serum, and Tissue Concentrations

    William H. Daughaday;Peter Rotwein

  • Growth, differentiation, and survival: multiple physiological functions for insulin-like growth factors

    Claire E.H. Stewart;Peter Rotwein

  • Characterization of the human growth hormone receptor gene and demonstration of a partial gene deletion in two patients with Laron-type dwarfism.

    Paul J. Godowski;David W. Leung;Lillian R. Meacham;John P. Galgani

  • Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality.

    Michele M.H. Lau;Claire E.H. Stewart;Ziying Liu;Harshida Bhatt

  • Differential expression of insulin-like growth factor genes in rat central nervous system.

    Peter Rotwein;Susan K. Burgess;Jeffrey D. Milbrandt;James. E. Krause

  • Organization and sequence of the human insulin-like growth factor I gene. Alternative RNA processing produces two insulin-like growth factor I precursor peptides.

    P Rotwein;K M Pollock;D K Didier;G G Krivi

  • Synthesis and secretion of insulin-like growth factor II by a leiomyosarcoma with associated hypoglycemia.

    William H. Daughaday;Mary Ann Emanuele;Marion H. Brooks;Anthony L. Barbato

  • A Calcineurin-NFATc3-Dependent Pathway Regulates Skeletal Muscle Differentiation and Slow Myosin Heavy-Chain Expression

    Ulrike Delling;Jolana Tureckova;Hae W. Lim;Leon J. De Windt

  • Two insulin-like growth factor I messenger RNAs are expressed in human liver.

    Peter Rotwein

  • Structure, evolution, expression and regulation of insulin-like growth factors I and II.

    Peter Rotwein

  • Insulin-like growth factors (IGF) in muscle development. Expression of IGF-I, the IGF-I receptor, and an IGF binding protein during myoblast differentiation.

    S. E. Tollefsen;R. Lajara;Robert H. McCusker;D. R. Clemmons

  • Growth hormone rapidly activates insulin-like growth factor I gene transcription in vivo.

    David P. Bichell;Kiyoshi Kikuchi;Peter Rotwein

  • Insulin-like growth factor-II is an autocrine survival factor for differentiating myoblasts.

    Claire E.H. Stewart;Peter Rotwein

  • Insulin-like growth factor-mediated muscle cell survival: central roles for Akt and cyclin-dependent kinase inhibitor p21.

    Margaret A. Lawlor;Peter Rotwein

  • Insulin-like Growth Factor-mediated Muscle Differentiation COLLABORATION BETWEEN PHOSPHATIDYLINOSITOL 3-KINASE-Akt-SIGNALING PATHWAYS AND MYOGENIN

    Jolana Tureckova;Elizabeth M. Wilson;Jennifer L. Cappalonga;Peter Rotwein

  • Coordinate expression of insulin-like growth factor II and its receptor during muscle differentiation.

    Sherida E. Tollefsen;Jenny Levis Sadow;Peter Rotwein

  • Diminished growth and enhanced glucose metabolism in triple knockout mice containing mutations of insulin-like growth factor binding protein-3, -4, and -5.

    Yun Ning;Alwin G. P. Schuller;Sheri Bradshaw;Peter Rotwein

  • Acute Control of Insulin-like Growth Factor-I Gene Transcription by Growth Hormone through Stat5b

    Joachim Woelfle;Julia Billiard;Peter Rotwein

  • Mechanisms of growth hormone (GH) action. Identification of conserved Stat5 binding sites that mediate GH-induced insulin-like growth factor-I gene activation.

    Joachim Woelfle;Dennis J. Chia;Peter Rotwein

  • A highly conserved insulin-like growth factor-binding protein (IGFBP-5) is expressed during myoblast differentiation.

    Payton L. James;Stephanie B. Jones;Walker H. Busby;David R. Clemmons

Frequent Co-Authors

Ron G. Rosenfeld
Ron G. Rosenfeld Oregon Health & Science University
Larry L. David
Larry L. David Oregon Health & Science University
William R. Skach
William R. Skach Cystic Fibrosis Foundation
Thomas L. McCarthy
Thomas L. McCarthy Yale University
Michael Centrella
Michael Centrella Yale University
John E. Pintar
John E. Pintar Rutgers, The State University of New Jersey
John K. Belknap
John K. Belknap Oregon Health & Science University
Terry G. Unterman
Terry G. Unterman University of Illinois at Chicago
Philip J. S. Stork
Philip J. S. Stork Oregon Health & Science University
G. Giacomo Consalez
G. Giacomo Consalez Vita-Salute San Raffaele University

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