Nicolas Manel

Best Publications

• Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

  Ivaylo I. Ivanov;Koji Atarashi;Nicolas Manel;Eoin L. Brodie

  5065
  Citations

• Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine

  Ivaylo Ivanov Ivanov;Rosa de Llanos Frutos;Nicolas Manel;Keiji Yoshinaga

  2027
  Citations

• The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat.

  Nicolas Manel;Derya Unutmaz;Dan R Littman

  1743
  Citations

• Aicardi–Goutières syndrome and the type I interferonopathies

  Yanick J. Crow;Nicolas Manel

  939
  Citations

• Digoxin and its derivatives suppress Th17 cell differentiation by antagonizing RORγt activity

  Jun R. Huh;Monica W. L. Leung;Pengxiang Huang;Daniel A. Ryan

  613
  Citations

• The Ubiquitous Glucose Transporter GLUT-1 Is a Receptor for HTLV

  Nicolas Manel;Felix J. Kim;Sandrina Kinet;Naomi Taylor

  594
  Citations

• Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations

  Nadia Jeremiah;Bénédicte Neven;Matteo Gentili;Isabelle Callebaut

  568
  Citations

• A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

  Nicolas Manel;Brandon Hogstad;Yaming Wang;David E. Levy

  509
  Citations

• The Capsids of HIV-1 and HIV-2 Determine Immune Detection of the Viral cDNA by the Innate Sensor cGAS in Dendritic Cells

  Unknown

  443
  Citations

• Transmission of innate immune signaling by packaging of cGAMP in viral particles.

  Matteo Gentili;Joanna Kowal;Mercedes Tkach;Takeshi Satoh

  336
  Citations

• Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes.

  Silvia Cerboni;Nadia Jeremiah;Matteo Gentili;Ulf Gehrmann

  289
  Citations

• Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection

  Smita Srivastava;Selene K. Swanson;Nicolas Manel;Laurence Florens

  259
  Citations

• The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus

  Matteo Gentili;Xavier Lahaye;Francesca Nadalin;Guilherme P.F. Nader

  244
  Citations

• NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation

  Xavier Lahaye;Matteo Gentili;Aymeric Silvin;Cécile Conrad

  220
  Citations

• Susceptibility of human Th17 cells to human immunodeficiency virus and their perturbation during infection.

  Aimee El Hed;Alka Khaitan;Lina Kozhaya;Nicolas Manel

  206
  Citations

• Mutations in COPA lead to abnormal trafficking of STING to the Golgi and interferon signaling.

  Alice Lepelley;Maria José Martin-Niclós;Melvin Le Bihan;Joseph A. Marsh

  205
  Citations

• Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing

  Adrien Decque;Adrien Decque;Olivier Joffre;Olivier Joffre;Olivier Joffre;Joao G Magalhaes;Joao G Magalhaes;Jack-Christophe Cossec;Jack-Christophe Cossec

  154
  Citations

• Selective STING stimulation in dendritic cells primes antitumor T cell responses

  Unknown

  139
  Citations

• Extracellular vesicles containing ACE2 efficiently prevent infection by SARS-CoV-2 Spike protein-containing virus

  Federico Cocozza;Federico Cocozza;Nathalie Névo;Ester Piovesana;Ester Piovesana;Xavier Lahaye

  133
  Citations

• Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria

  Unknown

  119
  Citations