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Nicholas J. C. King

Nicholas J. C. King

D-Index & Metrics

Immunology

D-Index
60
Citations
10757
World Ranking
3358
National Ranking
141

Overview

Nicholas J. C. King is affiliated with the University of Sydney in Australia. Their research spans multiple fields within biomedical sciences, focusing on the mechanisms of immune response and inflammation, particularly in neurological and infectious disease contexts.

The scientist has contributed extensively to the understanding of neuroinflammation and neurodegeneration mechanisms. Their work also addresses immune cell function and interaction, single-cell and spatial transcriptomics, and the immune response in cancer and infectious diseases, including mosquito-borne diseases and COVID-19.

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Immune cells in cancer
  • Single-cell and spatial transcriptomics
  • Immune Cell Function and Interaction
  • Mosquito-borne diseases and control
  • SARS-CoV-2 and COVID-19 Research
  • Immune Response and Inflammation

King has published 74 papers in Medicine, 51 in Immunology and Microbiology, and 33 in Biochemistry, Genetics and Molecular Biology. Their subfields of study include Immunology, Molecular Biology, Infectious Diseases, Neurology, and Public Health, Environmental and Occupational Health.

  • Immunology
  • Molecular Biology
  • Infectious Diseases
  • Neurology
  • Public Health, Environmental and Occupational Health

Recent papers include:

  • Microglia and monocytes in inflammatory CNS disease: integrating phenotype and function (2021, Acta Neuropathologica)
  • Integration, exploration, and analysis of high-dimensional single-cell cytometry data using Spectre (2021, Cytometry Part A)
  • Integrated immune dynamics define correlates of COVID-19 severity and antibody responses (2021, Cell Reports Medicine)
  • Gliadin Nanoparticles Induce Immune Tolerance to Gliadin in Mouse Models of Celiac Disease (2020, Gastroenterology)
  • PLX5622 Reduces Disease Severity in Lethal CNS Infection by Off-Target Inhibition of Peripheral Inflammatory Monocyte Production (2022, Frontiers in Immunology)

Frequent co-authors include:

  • Alanna G. Spiteri
  • Thomas M. Ashhurst
  • Laurence Macia
  • Claire L. Wishart
  • Duan Ni

King's work has been featured in various publication venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Frontiers in Immunology
  • Cytometry Part A
  • mBio

Best Publications

  • Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis

    Daniel R Getts;Aaron J Martin;Derrick P McCarthy;Rachael L Terry

  • Ly6c+ “inflammatory monocytes” are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis

    Daniel R. Getts;Rachael L. Terry;Meghann Teague Getts;Marcus Müller

  • Therapeutic Inflammatory Monocyte Modulation Using Immune-Modifying Microparticles

    Daniel R. Getts;Daniel R. Getts;Rachael L. Terry;Rachael L. Terry;Meghann Teague Getts;Celine Deffrasnes

  • Molecules in focus: indoleamine 2,3-dioxygenase.

    Nicholas J.C. King;Shane R. Thomas

  • Langerhans Cells Migrate to Local Lymph Nodes Following Cutaneous Infection with an Arbovirus

    Linda J Johnston;Gary M Halliday;Nicholas J C King

  • Fc receptors in antibody‐dependent enhancement of viral infections

    Adam Taylor;Suan-Sin Foo;Roberto Bruzzone;Roberto Bruzzone;Luan Vu Dinh

  • CXCR3 Signaling Reduces the Severity of Experimental Autoimmune Encephalomyelitis by Controlling the Parenchymal Distribution of Effector and Regulatory T Cells in the Central Nervous System

    Marcus Müller;Sally L. Carter;Markus J. Hofer;Peter Manders

  • Harnessing nanoparticles for immune modulation

    Daniel R. Getts;Daniel R. Getts;Lonnie D. Shea;Stephen D. Miller;Nicholas J.C. King

  • Triamcinolone acetonide modulates permeability and intercellular adhesion molecule-1 (ICAM-1) expression of the ECV304 cell line: implications for macular degeneration.

    P. L. Penfold;L. Wen;M. C. Madigan;M. C. Gillies

  • Tolerance Induced by Apoptotic Antigen-Coupled Leukocytes Is Induced by PD-L1+ and IL-10–Producing Splenic Macrophages and Maintained by T Regulatory Cells

    Daniel R. Getts;Danielle M. Turley;Cassandra E. Smith;Christopher T. Harp

  • Immunopathology of flavivirus infections

    Nicholas J C King;Daniel R Getts;Meghann T Getts;Sabita Rana

  • Rhinovirus exposure impairs immune responses to bacterial products in human alveolar macrophages

    Brian G Oliver;Brian G Oliver;Sam Lim;Peter Wark;Vasile Laza-Stanca

  • Microglia and monocytes in inflammatory CNS disease: integrating phenotype and function.

    Alanna G Spiteri;Claire L Wishart;Roger Pamphlett;Roger Pamphlett;Giuseppe Locatelli

  • Coordinated Regulation and Widespread Cellular Expression of Interferon-Stimulated Genes (ISG) ISG-49, ISG-54, and ISG-56 in the Central Nervous System after Infection with Distinct Viruses

    Christie Wacher;Marcus Müller;Markus J. Hofer;Daniel R. Getts

  • Inflammatory monocytes and the pathogenesis of viral encephalitis

    Rachael L. Terry;Rachael L. Terry;Daniel R. Getts;Celine Deffrasnes;Caryn Van Vreden

  • Interleukin-1β But Not Tumor Necrosis Factor is Involved in West Nile Virus-Induced Langerhans Cell Migration from the Skin in C57BL/6 Mice

    Scott N. Byrne;Gary M. Halliday;Linda J. Johnston;Linda J. Johnston;Nicholas J.C. King

  • Integrated immune dynamics define correlates of COVID-19 severity and antibody responses.

    Marios Koutsakos;Louise C. Rowntree;Luca Hensen;Brendon Y. Chua;Brendon Y. Chua

  • Immunodeficient mice recover from infection with vaccinia virus expressing interferon-γ

    Maija R. J. Kohonen-Corish;Nicholas J. C. King;Cathy E. Woodhams;Ian A. Ramshaw

  • Influenza virus inhibits amiloride-sensitive Na+ channels in respiratory epithelia

    K. Kunzelmann;A. H. Beesley;N. J. King;G. Karupiah

  • Site-Specific Production of IL-6 in the Central Nervous System Retargets and Enhances the Inflammatory Response in Experimental Autoimmune Encephalomyelitis

    Albert Quintana;Marcus Müller;Ricardo F. Frausto;Raquel Ramos

  • Modulation of permeability and adhesion molecule expression by human choroidal endothelial cells.

    Philip L. Penfold;Li Wen;Michele C. Madigan;Nicholas J. C. King

Frequent Co-Authors

Iain L. Campbell
Iain L. Campbell University of Sydney
Stephen D. Miller
Stephen D. Miller Northwestern University
Brian G. Oliver
Brian G. Oliver Woolcock Institute of Medical Research
Robert V. Blanden
Robert V. Blanden Australian National University
Lonnie D. Shea
Lonnie D. Shea University of Michigan–Ann Arbor
Shisan Bao
Shisan Bao University of Sydney
Arno Müllbacher
Arno Müllbacher Australian National University
Karl Kunzelmann
Karl Kunzelmann University of Regensburg
Suresh Mahalingam
Suresh Mahalingam Griffith University
Izuru Matsumoto
Izuru Matsumoto University of Sydney

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