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François Bertucci

François Bertucci

D-Index & Metrics

Medicine

D-Index
106
Citations
38019
World Ranking
6584
National Ranking
194

Overview

François Bertucci is affiliated with Aix-Marseille University in France and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their work primarily focuses on oncology, pulmonary and respiratory medicine, molecular biology, cancer research, and pathology and forensic medicine.

The scientist's recent publications highlight significant studies in cancer research and treatment. Notable papers include:

  • Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets (2020, Cell Metabolism)
  • Outcome and molecular landscape of patients with PIK3CA-mutated metastatic breast cancer (2020, Annals of Oncology)
  • Comprehensive metabolomics expands precision medicine for triple-negative breast cancer (2022, Cell Research)
  • Pembrolizumab in soft-tissue sarcomas with tertiary lymphoid structures: a phase 2 PEMBROSARC trial cohort (2022, Nature Medicine)
  • An integrated tumor, immune and microbiome atlas of colon cancer (2023, Nature Medicine)

The research topics François Bertucci addresses cover multiple crucial areas in cancer biology and treatment, such as sarcoma diagnosis and treatment, cancer genomics and diagnostics, cancer immunotherapy and biomarkers, advanced breast cancer therapies, HER2/EGFR in cancer research, cancer cells and metastasis, and vascular tumors and angiosarcomas.

Frequent co-authors collaborating with this scientist include:

  • Pascal Finetti
  • Jean-Yves Blay
  • Emmanuelle Bompas
  • Nicolas Penel
  • Émilie Mamessier

François Bertucci publishes regularly in prominent scientific venues, with the most frequent publication outlets being:

  • Annals of Oncology
  • Cancers
  • Journal of Clinical Oncology
  • Cancer Research
  • European Journal of Cancer

The scientist's work integrates multiple disciplines within medicine and molecular biology to contribute to improved understanding and treatment of cancer, especially focusing on breast cancer subtypes, metastatic disease, and the tumor microenvironment.

Best Publications

  • Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature.

    Emmanuelle Charafe-Jauffret;Christophe Ginestier;Flora Iovino;Julien Wicinski

  • Aldehyde Dehydrogenase 1–Positive Cancer Stem Cells Mediate Metastasis and Poor Clinical Outcome in Inflammatory Breast Cancer

    Emmanuelle Charafe-Jauffret;Christophe Ginestier;Flora Iovino;Carole Tarpin

  • Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity

    Emilie Mamessier;Aude Sylvain;Marie-Laure Thibult;Gilles Houvenaeghel

  • Gene expression profiling of breast cell lines identifies potential new basal markers

    E Charafe-Jauffret;C Ginestier;F Monville;P Finetti

  • How basal are triple-negative breast cancers?

    François Bertucci;Pascal Finetti;Nathalie Cervera;Benjamin Esterni

  • Genomic characterization of metastatic breast cancers

    François Bertucci;Charlotte K. Y. Ng;Charlotte K. Y. Ng;Charlotte K. Y. Ng;Anne Patsouris;Nathalie Droin;Nathalie Droin;Nathalie Droin

  • Prognostic and predictive value of PDL1 expression in breast cancer

    Renaud Sabatier;Pascal Finetti;Emilie Mamessier;José Adelaide

  • Basal breast cancer: a complex and deadly molecular subtype.

    F Bertucci;P Finetti;D Birnbaum

  • Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters.

    François Bertucci;Sébastien Salas;Séverine Eysteries;Valéry Nasser

  • Integrated profiling of basal and luminal breast cancers.

    José Adélaïde;Pascal Finetti;Ismahane Bekhouche;Laetitia Repellini

  • Discontinuation of imatinib in patients with advanced gastrointestinal stromal tumours after 3 years of treatment: an open-label multicentre randomised phase 3 trial

    Axel Le Cesne;Isabelle Ray-Coquard;Binh Nguyen Bui;Antoine Adenis

  • CD47–signal regulatory protein-α (SIRPα) interactions form a barrier for antibody-mediated tumor cell destruction

    Xi Wen Zhao;Ellen M. van Beek;Karin Schornagel;Hans Van der Maaden

  • Gene expression profiling shows medullary breast cancer is a subgroup of basal breast cancers

    François Bertucci;Pascal Finetti;Nathalie Cervera;Emmanuelle Charafe-Jauffret

  • A refined molecular taxonomy of breast cancer

    M Guedj;L Marisa;A de Reynies;B Orsetti

  • Improved survival using specialized multidisciplinary board in sarcoma patients.

    J.-Y. Blay;P. Soibinet;N. Penel;E. Bompas

  • Molecular profiling of classical Hodgkin lymphoma tissues uncovers variations in the tumor microenvironment and correlations with EBV infection and outcome.

    Bruno Chetaille;François Bertucci;Pascal Finetti;Benjamin Esterni

  • Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets.

    Yue Gong;Peng Ji;Yun-Song Yang;Shao Xie

  • Genomic Characterization of Primary Invasive Lobular Breast Cancer

    Christine Desmedt;Gabriele Zoppoli;Gunes Gundem;Giancarlo Pruneri

  • Gene expression profiling of primary breast carcinomas using arrays of candidate genes

    Francois Bertucci;Remi Houlgatte;Daniel Birnbaum;Catherine Nguyen

  • Gene Expression Profiling Identifies Molecular Subtypes of Inflammatory Breast Cancer

    François Bertucci;Pascal Finetti;Jacques Rougemont;Emmanuelle Charafe-Jauffret

Frequent Co-Authors

Patrice Viens
Patrice Viens Aix-Marseille University
Christine Chevreau
Christine Chevreau DuPont (United States)
Jean-Yves Blay
Jean-Yves Blay Claude Bernard University Lyon 1
Jocelyne Jacquemier
Jocelyne Jacquemier Grenoble Alpes University
Axel Le Cesne
Axel Le Cesne Institut Gustave Roussy
Antoine Italiano
Antoine Italiano University of Bordeaux
David Jérémie Birnbaum
David Jérémie Birnbaum Aix-Marseille University
Isabelle Ray-Coquard
Isabelle Ray-Coquard Claude Bernard University Lyon 1

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