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Kok P. M. van Kessel

Kok P. M. van Kessel

D-Index & Metrics

Microbiology

D-Index
56
Citations
11726
World Ranking
3695
National Ranking
142

Overview

Kok P. M. van Kessel is a researcher affiliated with Utrecht University in the Netherlands, focusing on diverse topics within medicine, immunology, and molecular biology. Their work primarily explores the immune system's interaction with bacterial infections, particularly with Staphylococcus species.

They have contributed extensively to subfields including immunology, infectious diseases, molecular biology, and radiology, nuclear medicine, and imaging. Their research themes encompass monoclonal and polyclonal antibodies, antimicrobial resistance in Staphylococcus, biochemical and structural characterization of immune components, complement system involvement in diseases, bacterial infections and vaccine development, immune response and inflammation, as well as bacterial biofilms and quorum sensing.

Van Kessel has published in a range of scientific venues with multiple contributions in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • Proceedings of the National Academy of Sciences
  • Scientific Reports
  • The Journal of Immunology

Frequent coauthors include Jos A. G. van Strijp, Suzan H. M. Rooijakkers, Piet C. Aerts, Carla J. C. de Haas, and Frank J. Beurskens, each collaborating on a significant number of publications, indicating ongoing research partnerships.

Key recent papers authored by or involving van Kessel include:

  • "Staphylococcal protein A inhibits complement activation by interfering with IgG hexamer formation," 2021, Proceedings of the National Academy of Sciences
  • "Use of Flow Cytometry to Evaluate Phagocytosis of Staphylococcus aureus by Human Neutrophils," 2021, Frontiers in Immunology
  • "C1q binding to surface-bound IgG is stabilized by C1r 2 s 2 proteases," 2021, Proceedings of the National Academy of Sciences
  • "Purified complement C3b triggers phagocytosis and activation of human neutrophils via complement receptor 1," 2023, Scientific Reports
  • "The Orphan Immune Receptor LILRB3 Modulates Fc Receptor-Mediated Functions of Neutrophils," 2020, The Journal of Immunology

The research profile of Kok P. M. van Kessel shows a strong engagement with understanding immune mechanisms, especially focused on complement system modulation and phagocytosis processes linked to bacterial pathogens. Their work integrates immunological techniques and molecular characterization, contributing to the broader fields of infectious diseases and immunology.

Best Publications

  • Staphylococcus aureus resistance to human defensins and evasion of neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with L-lysine

    Andreas Peschel;Andreas Peschel;Ralph W. Jack;Michael Otto;L. Vincent Collins

  • The Innate Immune Modulators Staphylococcal Complement Inhibitor and Chemotaxis Inhibitory Protein of Staphylococcus aureus Are Located on β-Hemolysin-Converting Bacteriophages

    Willem J. B. van Wamel;Suzan H. M. Rooijakkers;Maartje Ruyken;Kok P. M. van Kessel

  • Chemotaxis Inhibitory Protein of Staphylococcus aureus, a Bacterial Antiinflammatory Agent

    Carla J.C. de Haas;Karin Ellen Veldkamp;Andreas Peschel;Andreas Peschel;Floor Weerkamp

  • Immune evasion by a staphylococcal complement inhibitor that acts on C3 convertases.

    Suzan H M Rooijakkers;Maartje Ruyken;Anja Roos;Mohamed R Daha

  • Lipoprotein metabolism in patients with severe sepsis

    Henk J. van Leeuwen;Eric C. J. M. Heezius;Geesje M. Dallinga;Jos A. G. van Strijp

  • The Staphylococcal Toxin Panton-Valentine Leukocidin Targets Human C5a Receptors

    András N. Spaan;Thomas Henry;Willemien J.M. van Rooijen;Magali Perret

  • Staphylococcal innate immune evasion

    Suzan H.M. Rooijakkers;Kok P.M. van Kessel;Jos A.G. van Strijp

  • Staphylococcus aureus Strains Lacking d-Alanine Modifications of Teichoic Acids Are Highly Susceptible to Human Neutrophil Killing and Are Virulence Attenuated in Mice

    L. Vincent Collins;Sascha A. Kristian;Christopher Weidenmaier;Marion Faigle

  • Chemotaxis inhibitory protein of Staphylococcus aureus binds specifically to the C5a and formylated peptide receptor.

    Bent Postma;Miriam J. Poppelier;Joost C. van Galen;Eric R. Prossnitz

  • Staphylococcal complement evasion by various convertase-blocking molecules

    Ilse Jongerius;Jörg Köhl;Manoj K. Pandey;Maartje Ruyken

  • Staphylococcal superantigen-like 5 binds PSGL-1 and inhibits P-selectin–mediated neutrophil rolling

    Jovanka Bestebroer;Miriam J. J. G. Poppelier;Laurien H. Ulfman;Peter J. Lenting

  • Quantitation of surface CD14 on human monocytes and neutrophils.

    Peter Antal-Szalmas;Jos A. G. van Strijp;Annemarie J. L. Weersink;Jan Verhoef

  • Neutrophil-Mediated Phagocytosis of Staphylococcus aureus.

    Kok P. M. van Kessel;Jovanka Bestebroer;Jos A. G. van Strijp

  • Plasma vascular endothelial growth factor in severe sepsis.

    Michiel van der Flier;Henk J van Leeuwen;Kok P van Kessel;Jan L Kimpen

  • Pseudomonas evades immune recognition of flagellin in both mammals and plants

    Bart W. Bardoel;Sjoerd van der Ent;Michiel J. C. Pel;Jan Tommassen

  • Immune Evasion by Staphylococcus aureus.

    Nienke W. M. de Jong;Kok P. M. van Kessel;Jos A. G. van Strijp

  • A mutated B cell chronic lymphocytic leukemia subset that recognizes and responds to fungi

    Robbert Hoogeboom;Kok P.M. van Kessel;Frans Hochstenbach;Thera A. Wormhoudt

  • The staphylococcal toxins γ-haemolysin AB and CB differentially target phagocytes by employing specific chemokine receptors

    Andras N. Spaan;Manouk Vrieling;Pierre Wallet;Cedric Badiou

  • A New Staphylococcal Anti-Inflammatory Protein That Antagonizes the Formyl Peptide Receptor-Like 1

    Cristina Prat;Cristina Prat;Jovanka Bestebroer;Carla J. C. de Haas;Jos A. G. van Strijp

  • Early expression of SCIN and CHIPS drives instant immune evasion by Staphylococcus aureus.

    Suzan H M Rooijakkers;Maartje Ruyken;Jos van Roon;Kok P M van Kessel

  • Clumping factor A of Staphylococcus aureus inhibits phagocytosis by human polymorphonuclear leucocytes.

    Judy Higgins;Anthony Loughman;Kok P.M. Van Kessel;Jos A.G. Van Strijp

Frequent Co-Authors

Jos A. G. van Strijp
Jos A. G. van Strijp Utrecht University
Jan Verhoef
Jan Verhoef Utrecht University
Thomas Henry
Thomas Henry Claude Bernard University Lyon 1
François Vandenesch
François Vandenesch Claude Bernard University Lyon 1
Andreas Peschel
Andreas Peschel University of Tübingen
Michael P. Jennings
Michael P. Jennings Griffith University
Gerard Lina
Gerard Lina Claude Bernard University Lyon 1
Jörg Köhl
Jörg Köhl University of Lübeck
Victor J. Torres
Victor J. Torres New York University
Victor P.M.G. Rutten
Victor P.M.G. Rutten University of Pretoria

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