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Jan Paul Medema

Jan Paul Medema

Amsterdam UMC
Netherlands

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Medicine 90 11994 11284 463 449 409 42982

Jan Paul Medema publications per year

The chart shows the history of publications by Jan Paul Medema between 1964 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Jan Paul Medema published across 62 years, from 1964 to 2025, averaging 8 papers a year. Output peaked at 123 publications in 2023. 26 of the 498 publications appeared in the last two years.

No. of publications
25 50 75 100
Bar chart. Horizontal axis: year, 1964 to 2025. Vertical axis: number of publications, 0 to 123. Peak 123 publications in 2023. 1964: 1 publication 1965: 0 publications 1966: 0 publications 1967: 0 publications 1968: 0 publications 1969: 0 publications 1970: 1 publication 1971: 0 publications 1972: 0 publications 1973: 0 publications 1974: 0 publications 1975: 0 publications 1976: 0 publications 1977: 0 publications 1978: 0 publications 1979: 1 publication 1980: 0 publications 1981: 0 publications 1982: 0 publications 1983: 0 publications 1984: 0 publications 1985: 0 publications 1986: 0 publications 1987: 0 publications 1988: 0 publications 1989: 0 publications 1990: 0 publications 1991: 0 publications 1992: 0 publications 1993: 4 publications 1994: 4 publications 1995: 3 publications 1996: 1 publication 1997: 8 publications 1998: 2 publications 1999: 7 publications 2000: 1 publication 2001: 8 publications 2002: 8 publications 2003: 6 publications 2004: 6 publications 2005: 6 publications 2006: 9 publications 2007: 8 publications 2008: 17 publications 2009: 16 publications 2010: 14 publications 2011: 14 publications 2012: 16 publications 2013: 18 publications 2014: 18 publications 2015: 26 publications 2016: 28 publications 2017: 21 publications 2018: 14 publications 2019: 11 publications 2020: 22 publications 2021: 18 publications 2022: 12 publications 2023: 123 publications 2024: 16 publications 2025: 10 publications
1964 2025

498 publications in total across all disciplines

View publications per year as a table
Jan Paul Medema: publications per year, 1964 to 2025
Year Publications
1964 1
1965 0
1966 0
1967 0
1968 0
1969 0
1970 1
1971 0
1972 0
1973 0
1974 0
1975 0
1976 0
1977 0
1978 0
1979 1
1980 0
1981 0
1982 0
1983 0
1984 0
1985 0
1986 0
1987 0
1988 0
1989 0
1990 0
1991 0
1992 0
1993 4
1994 4
1995 3
1996 1
1997 8
1998 2
1999 7
2000 1
2001 8
2002 8
2003 6
2004 6
2005 6
2006 9
2007 8
2008 17
2009 16
2010 14
2011 14
2012 16
2013 18
2014 18
2015 26
2016 28
2017 21
2018 14
2019 11
2020 22
2021 18
2022 12
2023 123
2024 16
2025 10
Total 498
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Jan Paul Medema publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Jan Paul Medema sits on this spectrum.

No. of scientists
200 400 600 800
Bar chart with 86 bars. Horizontal axis: publications, 101–120 to 1,796+. Vertical axis: number of scientists, 0 to 922. Most scientists, 922, have 341–360 publications. The last bar groups every scientist with 1,796 publications or more. The highlighted bar, 401–420 publications, is where this scientist sits. 101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 610 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101–120 publications 1,796+

This scientist: 409 publications — 40th percentile

40% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

View publications distribution as a table
Number of Medicine scientists by publication count, Research.com 2026 ranking edition. Based on 20,134 ranked scientists.
Publications Scientists This scientist
101–120 5
121–140 26
141–160 73
161–180 155
181–200 230
201–220 363
221–240 487
241–260 545
261–280 722
281–300 768
301–320 834
321–340 895
341–360 922
361–380 838
381–400 861
401–420 918 409
421–440 806
441–460 771
461–480 751
481–500 713
501–520 617
521–540 610
541–560 537
561–580 504
581–600 509
601–620 396
621–640 386
641–660 371
661–680 340
681–700 336
701–720 307
721–740 259
741–760 230
761–780 228
781–800 217
801–820 204
821–840 186
841–860 177
861–880 155
881–900 139
901–920 145
921–940 116
941–960 133
961–980 91
981–1,000 96
1,001–1,020 77
1,021–1,040 70
1,041–1,060 63
1,061–1,080 77
1,081–1,100 49
1,101–1,120 54
1,121–1,140 49
1,141–1,160 51
1,161–1,180 35
1,181–1,200 39
1,201–1,220 26
1,221–1,240 37
1,241–1,260 36
1,261–1,280 27
1,281–1,300 32
1,301–1,320 28
1,321–1,340 17
1,341–1,360 30
1,361–1,380 28
1,381–1,400 17
1,401–1,420 21
1,421–1,440 15
1,441–1,460 12
1,461–1,480 12
1,481–1,500 18
1,501–1,520 14
1,521–1,540 17
1,541–1,560 15
1,561–1,580 6
1,581–1,600 2
1,601–1,620 12
1,621–1,640 11
1,641–1,660 8
1,661–1,680 5
1,681–1,700 5
1,701–1,720 10
1,721–1,740 12
1,741–1,760 14
1,761–1,780 6
1,781–1,795 5
1,796+ 100
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Jan Paul Medema D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Jan Paul Medema sits on this spectrum.

No. of scientists
250 500 750 1,000
Bar chart with 75 bars. Horizontal axis: D-Index, 70–71 to 217+. Vertical axis: number of scientists, 0 to 1,027. Most scientists, 1,027, have 82–83 D-Index. The last bar groups every scientist with 217 D-Index or more. The highlighted bar, 90–91 D-Index, is where this scientist sits. 70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 399 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70–71 D-Index 217+

This scientist: 90 D-Index — 41st percentile

41% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

View D-Index distribution as a table
Number of Medicine scientists by D-index, Research.com 2026 ranking edition. Based on 20,134 ranked scientists.
D-Index Scientists This scientist
70–71 226
72–73 391
74–75 574
76–77 730
78–79 891
80–81 972
82–83 1,027
84–85 1,003
86–87 960
88–89 970
90–91 922 90
92–93 839
94–95 808
96–97 779
98–99 668
100–101 611
102–103 630
104–105 513
106–107 541
108–109 445
110–111 429
112–113 399
114–115 393
116–117 318
118–119 302
120–121 287
122–123 255
124–125 256
126–127 252
128–129 230
130–131 179
132–133 168
134–135 163
136–137 159
138–139 134
140–141 134
142–143 118
144–145 109
146–147 106
148–149 74
150–151 79
152–153 80
154–155 87
156–157 57
158–159 74
160–161 69
162–163 60
164–165 53
166–167 39
168–169 42
170–171 32
172–173 39
174–175 40
176–177 28
178–179 19
180–181 23
182–183 31
184–185 18
186–187 20
188–189 22
190–191 13
192–193 21
194–195 12
196–197 12
198–199 14
200–201 15
202–203 13
204–205 10
206–207 8
208–209 4
210–211 12
212–213 11
214–215 10
216 4
217+ 98
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Overview

Jan Paul Medema is affiliated with Amsterdam UMC in the Netherlands and has made significant contributions in the fields of medicine and biochemistry, genetics, and molecular biology. Their research primarily focuses on oncology, with particular attention to colorectal cancer and cancer-related molecular mechanisms.

The scientist's work spans several subfields including oncology, molecular biology, pathology and forensic medicine, cancer research, and surgery. The main topics covered in their research include genetic factors in colorectal cancer, colorectal cancer treatments and studies, cancer cells and metastasis, pancreatic and hepatic oncology research, cancer genomics and diagnostics, colorectal cancer surgical treatments, and digestive system and related health issues.

Their recent publications highlight several aspects of cancer biology and potential therapeutic strategies. Notable papers include:

  • The Role of Cancer-Associated Fibroblasts in Cancer Invasion and Metastasis, 2021, published in Cancers
  • Apc-mutant cells act as supercompetitors in intestinal tumour initiation, 2021, published in Nature
  • BCL-2 family deregulation in colorectal cancer: potential for BH3 mimetics in therapy, 2020, published in APOPTOSIS
  • Molecular characterization of colorectal cancer related peritoneal metastatic disease, 2022, published in Nature Communications
  • PI3K-driven HER2 expression is a potential therapeutic target in colorectal cancer stem cells, 2021, published in Gut

Jan Paul Medema frequently collaborates with several co-authors, including Jan Köster, Maarten F. Bijlsma, Louis Vermeulen, Arezo Torang, and Hanneke W.M. van Laarhoven. Their publication record is concentrated in notable venues such as Nature Communications, bioRxiv (Cold Spring Harbor Laboratory), Cancers, BMC Cancer, and Research Square.

Their body of work encompasses a total of 131 publications within the broader medical field and 55 in biochemistry, genetics, and molecular biology. Oncology accounts for the majority of their contributions, underscoring a consistent focus on cancer biology and treatment research.

Best Publications

  • The consensus molecular subtypes of colorectal cancer

    Justin Guinney;Rodrigo Dienstmann;Rodrigo Dienstmann;Xingwu Wang;Xingwu Wang;Aurélien De Reyniès

  • FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

    Jan Paul Medema;Carsten Scaffidi;Frank C. Kischkel;Andrej Shevchenko

  • Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4.

    Matilde Todaro;Mileidys Perez Alea;Anna B. Di Stefano;Patrizia Cammareri

  • Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

    L. Galluzzi;J. M. Bravo-San Pedro;I. Vitale;S. A. Aaronson

  • Sequential cancer mutations in cultured human intestinal stem cells

    Jarno Drost;Richard H. van Jaarsveld;Bas Ponsioen;Cheryl Zimberlin

  • Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

    L. Galluzzi;L. Galluzzi;L. Galluzzi;S. A. Aaronson;J. Abrams;E. S. Alnemri

  • Elucidating the Autoimmune and Antitumor Effector Mechanisms of a Treatment Based on Cytotoxic T Lymphocyte Antigen-4 Blockade in Combination with a B16 Melanoma Vaccine Comparison of Prophylaxis and Therapy

    A. Van Elsas;R. P M Sutmuller;A. A. Hurwitz;J. Ziskin

  • The AC133 Epitope, but not the CD133 Protein, Is Lost upon Cancer Stem Cell Differentiation

    Kristel Kemper;Martin R. Sprick;Martijn de Bree;Alessandro Scopelliti

  • Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors

    J. P. Medema;J. de Jong;L. T. C. Peltenburg;E. M. E. Verdegaal

  • Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein.

    J. P. Medema;J. De Jong;T. Van Hall;C. J. M. Melief

  • Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis.

    Rene Jackstadt;Sander R. van Hooff;Joshua D. Leach;Xabier Cortes-Lavaud

  • Methylation of Cancer-Stem-Cell-Associated Wnt Target Genes Predicts Poor Prognosis in Colorectal Cancer Patients

    Felipe de Sousa E Melo;Selcuk Colak;Joyce Buikhuisen;Jan Koster

  • APRIL modulates B and T cell immunity.

    Jens V. Stein;Marta López-Fraga;Fernando A. Elustondo;Carla E. Carvalho-Pinto

  • CD40 stimulation leads to effective therapy of CD40(-) tumors through induction of strong systemic cytotoxic T lymphocyte immunity.

    Geertje J. D. van Mierlo;Annemieke Th. den Boer;Jan Paul Medema;Ellen I. H. van der Voort

  • Granzyme B-Dependent Proteolysis Acts as a Switch to Enhance the Proinflammatory Activity of IL-1α

    Inna S. Afonina;Graham A. Tynan;Susan E. Logue;Sean P. Cullen

  • Expression of the serpin serine protease inhibitor 6 protects dendritic cells from cytotoxic T lymphocyte-induced apoptosis: differential modulation by T helper type 1 and type 2 cells.

    Jan Paul Medema;Danita H. Schuurhuis;Delphine Rea;Joost van Tongeren

  • Monoclonal Antibodies Against Lgr5 Identify Human Colorectal Cancer Stem Cells

    Kristel Kemper;Pramudita R. Prasetyanti;Wim De Lau;Hans Rodermond

  • Heparan sulfate proteoglycan binding promotes APRIL-induced tumor cell proliferation

    J Hendriks;L Planelles;J de Jong-Odding;G Hardenberg

  • Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study

    Enric Domingo;Enric Domingo;Luke Freeman-Mills;Emily Rayner;Mark Glaire

  • Strategies for immunotherapy of cancer

    C J Melief;R E Toes;J P Medema;S H van der Burg

Frequent Co-Authors

Michael Hahne
Michael Hahne Centre national de la recherche scientifique, CNRS
Carlos Martínez-A
Carlos Martínez-A Spanish National Research Council
Wilson Savino
Wilson Savino Oswaldo Cruz Foundation
Marcel Spaargaren
Marcel Spaargaren University of Amsterdam
Eric Eldering
Eric Eldering University of Amsterdam
Tom van der Poll
Tom van der Poll University of Amsterdam

External Links

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Best Scientists Citing Jan Paul Medema

Michael Hahne

Michael Hahne

Centre national de la recherche scientifique, CNRS

Publications: 23

William Stohl

William Stohl

University of Southern California

Publications: 19

Pascal Schneider

Pascal Schneider

University of Lausanne

Publications: 19

Fabienne Mackay

Fabienne Mackay

QIMR Berghofer Medical Research Institute

Publications: 18

Michael P. Cancro

Michael P. Cancro

University of Pennsylvania

Publications: 15

Jan Paul Medema

Jan Paul Medema

University of Amsterdam

Publications: 15

Raif S. Geha

Raif S. Geha

Boston Children's Hospital

Publications: 10

Andrea Cerutti

Andrea Cerutti

Icahn School of Medicine at Mount Sinai

Publications: 9

Carlo M. Croce

Carlo M. Croce

The Ohio State University

Publications: 8

Stuart G. Tangye

Stuart G. Tangye

Garvan Institute of Medical Research

Publications: 8

Jakob Passweg

Jakob Passweg

University Hospital of Basel

Publications: 6

Stephen M. Ansell

Stephen M. Ansell

Mayo Clinic

Publications: 6

Thomas J. Kipps

Thomas J. Kipps

University of California, San Diego

Publications: 6

John De Vos

John De Vos

University of Montpellier

Publications: 5

Eric Eldering

Eric Eldering

University of Amsterdam

Publications: 5

Thierry Rème

Thierry Rème

Grenoble Alpes University

Publications: 5

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