James L. Riley

Overview

Best Publications

• CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms

  Richard V. Parry;Jens M. Chemnitz;Kenneth A. Frauwirth;Anthony R. Lanfranco

  2299
  Citations

• The CD28 signaling pathway regulates glucose metabolism.

  Kenneth A Frauwirth;James L Riley;Marian H Harris;Richard V Parry

  1654
  Citations

• Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo

  Michael C. Milone;Jonathan D. Fish;Jonathan D. Fish;Carmine Carpenito;Richard G. Carroll

  1451
  Citations

• Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

  Elena E. Perez;Jianbin Wang;Jeffrey C. Miller;Yann Jouvenot;Yann Jouvenot

  1362
  Citations

• SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation.

  Jens M. Chemnitz;Richard V. Parry;Kim E. Nichols;Carl H. June

  1185
  Citations

• Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains

  Carmine Carpenito;Michael C. Milone;Raffit Hassan;Jacqueline C. Simonet

  1078
  Citations

• Cutting Edge: Regulatory T Cells from Lung Cancer Patients Directly Inhibit Autologous T Cell Proliferation

  Edward Y. Woo;Heidi Yeh;Christina S. Chu;Katia Schlienger

  982
  Citations

• PD-1 signaling in primary T cells.

  James L. Riley

  946
  Citations

• Decade-Long Safety and Function of Retroviral-Modified Chimeric Antigen Receptor T Cells

  John Scholler;Troy L. Brady;Gwendolyn Binder-Scholl;Wei-Ting Hwang

  766
  Citations

• Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells

  Brian J. Cameron;Andrew B. Gerry;Joseph Dukes;Jane V. Harper

  755
  Citations

• Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB.

  Marcela V. Maus;Anna K. Thomas;Debra G.B. Leonard;David Allman

  615
  Citations

• PSMA-targeting TGFβ-insensitive armored CAR T cells in metastatic castration-resistant prostate cancer: a phase 1 trial

  Unknown

  611
  Citations

• Expression of a Functional CCR2 Receptor Enhances Tumor Localization and Tumor Eradication by Retargeted Human T Cells Expressing a Mesothelin - Specific Chimeric Antibody Receptor

  Edmund K. Moon;Carmine Carpenito;Jing Sun;Liang-Chuan S. Wang

  575
  Citations

• Human T Regulatory Cell Therapy: Take a Billion or So and Call Me in the Morning

  James L. Riley;Carl H. June;Bruce R. Blazar

  525
  Citations

• The PDL1-PD1 axis converts human TH1 cells into regulatory T cells.

  Shoba Amarnath;Courtney W. Mangus;Courtney W. Mangus;James C. M. Wang;Fang Wei

  522
  Citations

• Role of PD-1 during effector CD8 T cell differentiation.

  Eunseon Ahn;Koichi Araki;Masao Hashimoto;Weiyan Li

  489
  Citations

• FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression

  Bin Li;Arabinda Samanta;Xiaomin Song;Kathryn T. Iacono

  482
  Citations

• Chronic Virus Infection Enforces Demethylation of the Locus that Encodes PD-1 in Antigen-Specific CD8+ T Cells

  Benjamin Alan Youngblood;Kenneth J. Oestreich;Kenneth J. Oestreich;Sang-Jun Ha;Sang-Jun Ha;Jaikumar Duraiswamy

  458
  Citations

• DC-SIGN and DC-SIGNR bind ebola glycoproteins and enhance infection of macrophages and endothelial cells.

  Graham Simmons;Jacqueline D. Reeves;Case C. Grogan;Luk H. Vandenberghe

  455
  Citations

• Multifactorial T-cell Hypofunction That Is Reversible Can Limit the Efficacy of Chimeric Antigen Receptor–Transduced Human T cells in Solid Tumors

  Edmund K. Moon;Liang-Chuan Wang;Douglas V. Dolfi;Caleph B. Wilson

  451
  Citations

• The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation.

  James L. Riley;Carl H. June

  418
  Citations

• CTLA-4 and PD-1 Receptors Inhibit T-Cell Activation by Distinct Mechanisms.

  Jens M. Chemnitz;James L. Riley;Kenneth A. Frauwirth;Inbal Braunstein

  29
  Citations