James Dooley

Best Publications

• Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3

  Jason D. Fontenot;Jeffrey P. Rasmussen;Luke M. Williams;James L. Dooley

  2887
  Citations

• Developmental regulation of Foxp3 expression during ontogeny

  Jason D. Fontenot;James L. Dooley;Andrew G. Farr;Alexander Y. Rudensky

  607
  Citations

• Histamine Receptor H1-Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome

  Mira M. Wouters;Dafne Balemans;Sander Van Wanrooy;James Dooley

  376
  Citations

• The cellular composition of the human immune system is shaped by age and cohabitation

  Edward J Carr;James Dooley;Josselyn E Garcia-Perez;Vasiliki Lagou

  355
  Citations

• Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition.

  Emanuela Pasciuto;Oliver T. Burton;Carlos P. Roca;Vasiliki Lagou

  337
  Citations

• Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation

  Seth L. Masters;Seth L. Masters;Vasiliki Lagou;Isabelle Jéru;Isabelle Jéru;Paul J. Baker;Paul J. Baker

  309
  Citations

• Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3 + regulatory T cells

  Wim Pierson;Bénédicte Cauwe;Antonia Policheni;Antonia Policheni;Susan M Schlenner

  269
  Citations

• Notch ligands Delta1 and Jagged1 transmit distinct signals to T-cell precursors

  Sophie M. Lehar;James Dooley;James Dooley;Andrew G. Farr;Andrew G. Farr;Michael J. Bevan;Michael J. Bevan

  263
  Citations

• Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation

  Unknown

  253
  Citations

• The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor

  Aikaterini S Papadopoulou;James Dooley;Michelle A Linterman;Wim Pierson

  204
  Citations

• Molecular control over thymic involution: From cytokines and microRNA to aging and adipose tissue

  Unknown

  196
  Citations

• Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy.

  Helena Van Damme;Bruno Dombrecht;Máté Kiss;Heleen Roose

  192
  Citations

• Aire-Dependent Alterations in Medullary Thymic Epithelium Indicate a Role for Aire in Thymic Epithelial Differentiation

  Geoffrey O. Gillard;James Dooley;Matthew Erickson;Leena Peltonen

  184
  Citations

• The microRNA-29 Family Dictates the Balance Between Homeostatic and Pathological Glucose Handling in Diabetes and Obesity

  James Dooley;Josselyn E. Garcia-Perez;Jayasree Sreenivasan;Susan M. Schlenner

  160
  Citations

• Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes

  James Dooley;Lei Tian;Susann Schonefeldt;Viviane Delghingaro-Augusto

  156
  Citations

• Organization of thymic medullary epithelial heterogeneity: implications for mechanisms of epithelial differentiation

  Andrew G. Farr;James L. Dooley;Matt Erickson

  148
  Citations

• Local increase in thymic stromal lymphopoietin induces systemic alterations in B cell development

  Alexander Astrakhan;Miyuki Omori;Thuc Nguyen;Shirly Becker-Herman

  139
  Citations

• Hematopoietic stem cell transplantation rescues the immunologic phenotype and prevents vasculopathy in patients with adenosine deaminase 2 deficiency

  Lien Van Eyck;Michael S. Hershfield;Diana Pombal;Susan J. Kelly

  136
  Citations

• MicroRNA-29 in the adaptive immune system: setting the threshold.

  Adrian Liston;Aikaterini S. Papadopoulou;Dina Danso-Abeam;James Dooley

  124
  Citations

• Psychological comorbidity increases the risk for postinfectious IBS partly by enhanced susceptibility to develop infectious gastroenteritis

  Mira M Wouters;Sander Van Wanrooy;Anh Nguyen;James Dooley

  109
  Citations