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D-Index & Metrics

Immunology

D-Index
82
Citations
23691
World Ranking
1506
National Ranking
759

Overview

Dean L. Mann is affiliated with the University of Maryland, Baltimore in the United States. Their research spans multiple fields within medicine and biochemistry, genetics, and molecular biology, with significant contributions to oncology, molecular biology, immunology, animal science and zoology, and hepatology.

The main topics of Dean L. Mann's work include:

  • Metabolism, Diabetes, and Cancer
  • Cancer-related Molecular Pathways
  • Viral-associated Cancers and Disorders
  • Animal Virus Infections Studies
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Liver Disease Diagnosis and Treatment
  • Endoplasmic Reticulum Stress and Disease

Recent publications by Dean L. Mann illustrate their research interests across cancer biology and immunotherapy. These include:

  • A Viral Exposure Signature Defines Early Onset of Hepatocellular Carcinoma, 2020, published in Cell
  • Genetic susceptibility to hepatocellular carcinoma in chromosome 22q13.31, findings of a genome-wide association study, 2021, published in JGH Open
  • Diabetes-associated breast cancer is molecularly distinct and shows a DNA damage repair deficiency, 2023, published in JCI Insight
  • One term to transform: universal health coverage through professional community health workers, 2024, published in The Lancet
  • Combined immunotherapy and radiation induce cellular and humoral immune responses to tumor-associated antigens and prolong survival of patients with advanced cancers, 2023, published in Medical Research Archives

The researcher has frequently published in the following venues:

  • Cell
  • JGH Open
  • JCI Insight
  • The Lancet
  • Medical Research Archives

Collaborations form a notable part of their work, with key frequent coauthors including:

  • Xin Wei Wang
  • Julián Candia
  • Stefan Ambs
  • Wei Tang
  • Gatikrushna Panigrahi

The interdisciplinary focus of Dean L. Mann's research integrates molecular biology and clinical aspects of oncology, particularly concentrating on cancer metabolism, viral influences on cancer development, and therapeutic approaches involving immunotherapy and radiation. This body of work contributes to understanding complex mechanisms in hepatocellular carcinoma and other cancer types associated with metabolic and DNA repair pathways.

Best Publications

  • Isolation of human T-cell leukemia virus in acquired immune deficiency syndrome (AIDS)

    Robert C. Gallo;Prem S. Sarin;E. P. Gelmann;Marjorie Robert-Guroff

  • Influence of combinations of human major histocompatibility complex genes on the course of HIV–1 infection

    Richard A. Kaslow;Mary Carrington;R. Apple;L. Park

  • Cellular proteins bound to immunodeficiency viruses: implications for pathogenesis and vaccines.

    Larry O. Arthur;Julian W. Bess;Raymond C. Sowder;Raoul E. Benveniste

  • Isolation and Transmission of Human Retrovirus (Human T-Cell Leukemia Virus)

    M Popovic;PS Sarin;M Robert-Gurroff;VS Kalyanaraman

  • A Prospective Study of Human Immunodeficiency Virus Type 1 Infection and the Development of AIDS in Subjects with Hemophilia

    James J. Goedert;Craig M. Kessler;Louis M. Aledort;Robert J. Biggar

  • Sjögren's Syndrome (Sicca Syndrome): Current Issues

    Haralampos M. Moutsopoulos;Thomas M. Chused;Dean L. Mann;John H. Klippel

  • Characterization of a monoclonal antibody (4F2) that binds to human monocytes and to a subset of activated lymphocytes.

    B F Haynes;M E Hemler;D L Mann;G S Eisenbarth

  • Epidermal langerhans cells—A target for HTLV-III/LAV infection

    Erwin Tschachler;Veronika Groh;Mikulas Popovic;Dean L Mann

  • DETERMINANTS OF RETROVIRUS (HTLV-III) ANTIBODY AND IMMUNODEFICIENCY CONDITIONS IN HOMOSEXUAL MEN

    James J. Goedert;Robert J. Biggar;Deborah M. Winn;Mark H. Greene

  • B-lymphocyte alloantigens associated with systemic lupus erythematosus.

    James L. Reinertsen;John H. Klippel;Armead H. Johnson;Alfred D. Steinberg

  • Effect of T4 count and cofactors on the incidence of AIDS in homosexual men infected with human immunodeficiency virus.

    James J. Goedert;Robert J. Biggar;Mads Melbye;Dean L. Mann

  • Restoration of immunity in lymphopenic individuals with cancer by vaccination and adoptive T-cell transfer

    Aaron P Rapoport;Edward A Stadtmauer;Nicole Aqui;Ashraf Badros

  • Characterization of a monoclonal antibody (5E9) that defines a human cell surface antigen of cell activation.

    B F Haynes;M Hemler;T Cotner;D L Mann

  • Isolation and immunologic characterization of a human. B-lymphocyte-specific, cell surface antigen.

    R E Humphreys;J M McCune;L Chess;H C Herrman

  • Differential DNA sequence deletions from chromosomes 3, 11, 13, and 17 in squamous-cell carcinoma, large-cell carcinoma, and adenocarcinoma of the human lung.

    A Weston;J C Willey;R Modali;H Sugimura

  • Interleukin-2 production used to detect antigenic peptide recognition by T-helper lymphocytes from asymptomatic HIV-seropositive individuals.

    Mario Clerici;Naomi I. Stocks;Robert A. Zajac;R. Neal Boswell

  • Detection of benzo[a]pyrene diol epoxide-DNA adducts in peripheral blood lymphocytes and antibodies to the adducts in serum from coke oven workers.

    Curtis C. Harris;Kirsi Vahakangas;Mark J. Newman;Glennwood E. Trivers

  • Human B-cell alloantigens DC1, MT1, and LB12 are identical to each other but distinct from the HLA-DR antigen

    Deborah A. Shackelford;Dean L. Mann;Jon J. van Rood;G. B. Ferrara

  • The effects of cigarette smoking on T cell subsets. A population-based survey of healthy caucasians.

    David J. Tollerud;Jeffrey W. Clark;Linda Morris Brown;Carolyn Y. Neuland

  • Human T-cell leukemia-lymphoma virus (HTLV) is in T but not B lymphocytes from a patient with cutaneous T-cell lymphoma

    R C Gallo;D Mann;S Broder;F W Ruscetti

  • Differentiation between African populations is evidenced by the diversity of alleles and haplotypes of HLA class I loci

    Kai Cao;A. M. Moormann;K. E. Lyke;C. Masaberg

Frequent Co-Authors

William A. Blattner
William A. Blattner University of Maryland, Baltimore
Mikulas Popovic
Mikulas Popovic University of Maryland, Baltimore
Robert C. Gallo
Robert C. Gallo University of South Florida
Jack L. Strominger
Jack L. Strominger Harvard University
Mary Carrington
Mary Carrington Ragon Institute of MGH, MIT and Harvard
James J. Goedert
James J. Goedert National Institutes of Health
Curtis C. Harris
Curtis C. Harris National Institutes of Health
Peter Parham
Peter Parham Stanford University
John L. Fahey
John L. Fahey University of California, Los Angeles
Bruce L. Levine
Bruce L. Levine University of Pennsylvania

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