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Genetics

D-Index
68
Citations
16355
World Ranking
2433
National Ranking
39

Overview

David Shore is affiliated with the University of Geneva in Switzerland and specializes in the field of Biochemistry, Genetics and Molecular Biology, with a particular emphasis on Molecular Biology. Their research encompasses several subfields including Oncology, Cell Biology, Cancer Research, and Physiology.

Their work primarily addresses topics related to RNA and protein synthesis mechanisms, RNA modifications and cancer, RNA research and splicing, ubiquitin and proteasome pathways, genomics and chromatin dynamics, fungal and yeast genetics research, and DNA repair mechanisms.

Notable recent publications by David Shore include:

  • Ribosome biogenesis and the cellular energy economy, 2022, published in Current Biology
  • Transcriptional control of ribosome biogenesis in yeast: links to growth and stress signals, 2021, published in Biochemical Society Transactions
  • Mechanisms coordinating ribosomal protein gene transcription in response to stress, 2020, published in Nucleic Acids Research
  • Approaching Protein Barriers: Emerging Mechanisms of Replication Pausing in Eukaryotes, 2021, published in Frontiers in Cell and Developmental Biology
  • Not1 and Not4 inversely determine mRNA solubility that sets the dynamics of co-translational events, 2023, published in Genome biology

David Shore has frequently collaborated with other researchers, including Benjamin Albert, Daniel Dilg, Sevil Zencir, Maria Paula Rueda, and George E. Allen. The number of collaborations varies, with the most frequent co-author being Benjamin Albert.

Publication venues where David Shore has contributed multiple papers include bioRxiv (Cold Spring Harbor Laboratory), Nucleic Acids Research, Current Biology, Biochemical Society Transactions, and Frontiers in Cell and Developmental Biology.

Best Publications

  • EVIDENCE THAT A COMPLEX OF SIR PROTEINS INTERACTS WITH THE SILENCER AND TELOMERE-BINDING PROTEIN RAP1

    Paolo Moretti;Katie Freeman;Lavanya Coodly;David Shore

  • Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements

    David Shore;Kim Nasmyth

  • A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation.

    C. F. J. Hardy;L. Sussel;D. Shore

  • A Protein-Counting Mechanism for Telomere Length Regulation in Yeast

    Stéphane Marcand;Eric Gilson;David M. Shore

  • DNA flexibility studied by covalent closure of short fragments into circles

    David Shore;Jorg Langowski;Robert L. Baldwin

  • A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae.

    David Wotton;David M. Shore

  • Energetics of DNA twisting: I. Relation between twist and cyclization probability*

    David Shore;Robert L. Baldwin

  • Chromosomal landscape of nucleosome-dependent gene expression and silencing in yeast

    John J. Wyrick;Frank C.P. Holstege;Ezra G. Jennings;Helen C. Causton

  • Involvement of the silencer and UAS binding protein RAP1 in regulation of telomere length

    Arthur J. Lustig;Stephen Kurtz;David Shore

  • Growth control and ribosome biogenesis.

    Harri Lempiäinen;David Shore

  • RAP1: a protean regulator in yeast

    David Shore

  • Cingulin Contains Globular and Coiled-Coil Domains and Interacts with Zo-1, Zo-2, Zo-3, and Myosin

    Michelangelo Cordenonsi;Fabio D'Atri;Eva Hammar;David A.D. Parry

  • Separation of transcriptional activation and silencing functions of the RAP1-encoded repressor/activator protein 1: isolation of viable mutants affecting both silencing and telomere length.

    Lori Sussel;David Shore

  • Energetics of DNA twisting: II. Topoisomer analysis*

    David Shore;Robert L. Baldwin

  • Growth-regulated recruitment of the essential yeast ribosomal protein gene activator Ifh1

    Stephan B. Schawalder;Mehdi Kabani;Isabelle Howald;Urmila Choudhury

  • Identification of silencer binding proteins from yeast: possible roles in SIR control and DNA replication

    David Shore;David J. Stillman;Andrea H. Brand;Kim A. Nasmyth

  • Targeting of SIR1 protein establishes transcriptional silencing at HM loci and telomeres in yeast

    Cheng-ting Chien;Stephen Buck;Rolf Sternglanz;David Shore

  • Characterization of two genes required for the position-effect control of yeast mating-type genes.

    D Shore;M Squire;K A Nasmyth

  • Action of a RAP1 carboxy-terminal silencing domain reveals an underlying competition between HMR and telomeres in yeast.

    Stephen W. Buck;David Shore

  • Transcriptional regulation in the yeast life cycle

    Kim Nasmyth;David Shore

Frequent Co-Authors

Kim Nasmyth
Kim Nasmyth University of Oxford
Lori Sussel
Lori Sussel University of Colorado Denver
Robert L. Baldwin
Robert L. Baldwin Stanford University
Massimo Lopes
Massimo Lopes University of Zurich
Felix Naef
Felix Naef École Polytechnique Fédérale de Lausanne
Sandra Citi
Sandra Citi University of Geneva
Robbie Loewith
Robbie Loewith University of Geneva
Frank C. P. Holstege
Frank C. P. Holstege Utrecht University
Charles Boone
Charles Boone University of Toronto
Brenda J. Andrews
Brenda J. Andrews University of Toronto

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