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Virginia A. Zakian

Virginia A. Zakian

D-Index & Metrics

Genetics

D-Index
83
Citations
28741
World Ranking
1407
National Ranking
664

Research.com Recognitions

  • 2019 - Fellow of the American Academy of Arts and Sciences
  • 2018 - Member of the National Academy of Sciences
  • 1992 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Virginia A. Zakian is affiliated with Princeton University in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant work in molecular biology, plant science, physiology, pathology and forensic medicine, and genetics.

Their recent publications cover various topics related to RNA and protein synthesis mechanisms, RNA research and splicing, CRISPR and genetic engineering, DNA repair mechanisms, fungal and yeast genetics research, chromosomal and genetic variations, and genomics and chromatin dynamics.

Examples of their published papers include:

  • Stability and nuclear localization of yeast telomerase depend on protein components of RNase P/MRP, 2020, Nature Communications
  • A new role for proteins subunits of RNase P: stabilization of the telomerase holoenzyme, 2020, Microbial Cell
  • Identification of the nuclear localization signal in the Saccharomyces cerevisiae Pif1 DNA helicase, 2023, PLoS Genetics
  • Pif1 family helicases promote mutation avoidance during DNA replication, 2022, Nucleic Acids Research
  • Highly Transcribed RNA Polymerase II Genes Are Impediments to Replication Fork Progression in Saccharomyces cerevisiae, 2020, UNC Libraries

Frequent co-authors in their research include P. Daniela Garcia, Robert Leach, Gable M. Wadsworth, Krishna Choudhary, and Hua Li.

The scholar's work has been published in journals such as Nature Communications, PLoS Genetics, Microbial Cell, Nucleic Acids Research, and UNC Libraries.

Awards received include:

  • Fellow of the American Academy of Arts and Sciences, 2019
  • Member of the National Academy of Sciences, 2018
  • Fellow of the American Association for the Advancement of Science (AAAS), 1992

Best Publications

  • Position Effect at S. cerevisiae Telomeres: Reversible Repression of Pol II Transcription

    Daniel E. Gottschling;Oscar M. Aparicio;Barbara L. Billington;Virginia A. Zakian

  • DNA secondary structures: stability and function of G-quadruplex structures

    Matthew L. Bochman;Katrin Paeschke;Virginia A. Zakian

  • Telomeres: Beginning to Understand the End

    Virginia A. Zakian

  • Loss of a yeast telomere: Arrest, recovery, and chromosome loss

    Lisa L. Sandell;Lisa L. Sandell;Virginia A. Zakian;Virginia A. Zakian

  • STRUCTURE AND FUNCTION OF TELOMERES

    Virginia A. Zakian

  • Telomere-Telomere Recombination Is an Efficient Bypass Pathway for Telomere Maintenance in Saccharomyces cerevisiae

    Shu Chun Teng;Virginia Araxie Zakian

  • DNA Replication through G-Quadruplex Motifs Is Promoted by the Saccharomyces cerevisiae Pif1 DNA Helicase

    Katrin Paeschke;John A. Capra;Virginia A. Zakian

  • RAP1 protein interacts with yeast telomeres in vivo: Overproduction alters telomere structure and decreases chromosome stability

    Michael N. Conrad;Jocelyn H. Wright;Jocelyn H. Wright;Alexander J. Wolf;Virginia A. Zakian

  • The Saccharomyces cerevisiae Helicase Rrm3p Facilitates Replication Past Nonhistone Protein-DNA Complexes

    Andreas S. Ivessa;Brian A. Lenzmeier;Jessica B. Bessler;Lara K. Goudsouzian

  • Saccharomyces telomeres acquire single-strand TG1–3 tails late in S phase

    Raymund J. Wellinger;Alexander J. Wolf;Virginia A. Zakian;Virginia A. Zakian

  • The saccharomyces PIF1 DNA helicase inhibits telomere elongation and de novo telomere formation

    Vincent P. Schulz;Virginia Araxie Zakian;Virginia Araxie Zakian

  • Pif1 family helicases suppress genome instability at G-quadruplex motifs

    Katrin Paeschke;Katrin Paeschke;Matthew L. Bochman;P. Daniela Garcia;Petr Cejka;Petr Cejka

  • Est1p As a Cell Cycle-Regulated Activator of Telomere-Bound Telomerase

    Andrew K. P. Taggart;Shu-Chun Teng;Virginia A. Zakian

  • Expansion and Length-Dependent Fragility of CTG Repeats in Yeast

    Catherine H. Freudenreich;Sara M. Kantrow;Virginia A. Zakian

  • The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase α and the telomerase-associated Est1 protein

    Haiyan Qi;Virginia A. Zakian

  • The Saccharomyces CDC13 protein is a single-strand TG1–3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo

    Jing-Jer Lin;Virginia A. Zakian

  • Evidence for a New Step in Telomere Maintenance

    Raymund J Wellinger;Katia Ethier;Pascale Labrecque;Virginia A Zakian

  • ATM-related genes: what do they tell us about functions of the human gene?

    Virginia A Zakian

  • Telomere proteins: specific recognition and protection of the natural termini of Oxytricha macronuclear DNA.

    Daniel E. Gottschling;Virginia Araxie Zakian

  • The Yeast Pif1 Helicase Prevents Genomic Instability Caused by G-Quadruplex-Forming CEB1 Sequences In Vivo

    Cyril Ribeyre;Judith Lopes;Jean Baptiste Boulé;Jean Baptiste Boulé;Aurèle Piazza

Frequent Co-Authors

Raymund J. Wellinger
Raymund J. Wellinger Université de Sherbrooke
Daniel E. Gottschling
Daniel E. Gottschling Fred Hutchinson Cancer Research Center
Taekjip Ha
Taekjip Ha Johns Hopkins University
Ileana M. Cristea
Ileana M. Cristea Princeton University
Walton L. Fangman
Walton L. Fangman University of Washington
Andrew Wakeham
Andrew Wakeham Princess Margaret Cancer Centre
Mary Claire King
Mary Claire King University of Washington
Bonita J. Brewer
Bonita J. Brewer University of Washington
Jeremy A. Squire
Jeremy A. Squire Universidade de São Paulo
Héctor D. Abruña
Héctor D. Abruña Cornell University

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