World's Best Scientists 2026 revealed!

Research.com Recognitions

  • 2000 - Member of the National Academy of Medicine (NAM)

Overview

William A. Knaus is affiliated with the University of Virginia in the United States and focuses primarily on the field of Medicine. Their research spans various subfields including Epidemiology, Cardiology and Cardiovascular Medicine, Emergency Medical Services, Pulmonary and Respiratory Medicine, and Emergency Medicine.

Their main topics of work include:

  • Sepsis Diagnosis and Treatment
  • Blood Pressure and Hypertension Studies
  • Disaster Response and Management
  • Respiratory Support and Mechanisms
  • Cardiac Arrest and Resuscitation
  • COVID-19 diagnosis using AI
  • Machine Learning in Healthcare

The scientist has published several recent papers, including:

  • "Severity of Illness and Predictive Models in Society of Critical Care Medicine's First 50 Years: A Tale of Concord and Conflict" (2021) in Critical Care Medicine
  • "TOWARD A COVID-19 SCORE-RISK ASSESSMENTS AND REGISTRY" (2020) in bioRxiv (Cold Spring Harbor Laboratory)
  • "Prognostic Modeling and Major Dataset Shifts During the COVID-19 Pandemic" (2022) in JAMA Health Forum
  • "The authors reply" (2021) in Critical Care Medicine
  • "All Public Health is Local" (2022) in Medical Care

Frequent collaborators in Knaus's research include Andrew A. Kramer, Jack E. Zimmerman, Cristina Vazquez Guillamet, Rodrigo Vazquez Guillamet, and Paula Maurer.

They have published predominantly in venues such as Critical Care Medicine, bioRxiv (Cold Spring Harbor Laboratory), JAMA Health Forum, Medical Care, and UNC Libraries.

Among professional recognitions, William A. Knaus was made a Member of the National Academy of Medicine (NAM) in 2000.

Best Publications

  • A controlled trial to improve care for seriously ill hospitalized patients: The study to understand prognoses and preferences for outcomes and risks of treatments (SUPPORT)

    Alfred F Connors;Neal V Dawson;N. A. Desbiens;W. J. Fulkerson

  • Outcomes following acute exacerbation of severe chronic obstructive lung disease. The SUPPORT investigators (Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments)

    Alfred F. Connors;Neal V. Dawson;Charles Thomas;Frank E. Harrell

  • The effectiveness of right heart catheterization in the initial care of critically ill patients. SUPPORT Investigators.

    Connors Af;Speroff T;Dawson Nv;Thomas C

  • Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome. Results from a randomized, double-blind, placebo-controlled trial. Phase III rhIL-1ra Sepsis Syndrome Study Group.

    Fisher Cj;Dhainaut Jf;Opal Sm;Pribble Jp

  • The performance of intensive care units: does good management make a difference?

    Stephen Shortell;Jack Zimmerman;Denise Rousseau;Robin Gillies

  • APACHE II-A Severity of Disease Classification System: Reply

    William A. Knaus;Elizabeth A. Draper;Douglas P. Wagner;Jack E. Zimmerman

  • The Impact of Serious Illness on Patients' Families

    Kenneth E. Covinsky;Kenneth E. Covinsky;Lee Goldman;E. Francis Cook;Robert Oye

  • Advance Directives for Seriously Ill Hospitalized Patients: Effectiveness with the Patient Self‐Determination Act and the SUPPORT Intervention

    Joan Teno;Joanne Lynn;Neil Wenger;Russell S. Phillips

  • Changes in hospital mortality for United States intensive care unit admissions from 1988 to 2012

    Jack E Zimmerman;Andrew A Kramer;William A Knaus

  • Influence of Patient Preferences and Local Health System Characteristics on the Place of Death

    Robert S. Pritchard;Elliott S. Fisher;Elliott S. Fisher;Joan M. Teno;Sandra M. Sharp

  • Do Advance Directives Provide Instructions That Direct Care

    Joan M Teno;Sandra Licks;Joanne Lynn;Neil Wenger

  • Factors Associated with Do-Not-Resuscitate Orders: Patients' Preferences, Prognoses, and Physicians' Judgments

    Rosemarie B. Hakim;Joan M. Teno;Frank E. Harrell;William A. Knaus

  • Broadband computer-based networked systems for control and management of medical records

    William A. Knaus;Richard D. Marks

  • Short-term mortality predictions for critically ill hospitalized adults: science and ethics.

    William A. Knaus;Douglas P. Wagner;Joanne Lynn

  • Impact of Patient Distance to Radiation Therapy on Mastectomy Use in Early-Stage Breast Cancer Patients

    Anneke T. Schroen;David R. Brenin;Maria D. Kelly;William A. Knaus

  • The clinical evaluation of new drugs for sepsis : a prospective study design based on survival analysis

    William A. Knaus;Frank E. Harrell;Charles J. Fisher;Douglas P. Wagner

  • A Predictive Risk Model for Outcomes of Ischemic Stroke

    K. C. Johnston;A. F. Connors;D. P. Wagner;W. A. Knaus

  • Family satisfaction with end-of-life care in seriously ill hospitalized adults.

    Rose Baker;Hyg;Albert W. Wu;Joan M. Teno

  • Interhospital comparisons of patient outcome from intensive care: importance of lead-time bias.

    Lis Dragsted;JÖrgen JÖrgensen;Niels-henrik Jensen;Else BÖnsing

  • Treatment of Severe Systemic Inflammatory Response Syndrome and Sepsis With a Novel Bradykinin Antagonist, Deltibant (CP-0127): Results of a Randomized, Double-blind, Placebo-Controlled Trial

    Alan M. Fein;Gordon R. Bernard;Gerard J. Criner;Eugene C. Fletcher

Frequent Co-Authors

Frank E. Harrell
Frank E. Harrell Vanderbilt University
Alfred F. Connors
Alfred F. Connors Case Western Reserve University
Joanne Lynn
Joanne Lynn Altarum Institute
Russell S. Phillips
Russell S. Phillips Harvard University
Joan M. Teno
Joan M. Teno Brown University
Neil S. Wenger
Neil S. Wenger University of California, Los Angeles
Albert W. Wu
Albert W. Wu Johns Hopkins University
Robert M. Califf
Robert M. Califf Duke University
Craig L. Slingluff
Craig L. Slingluff University of Virginia
Stephen M. Shortell
Stephen M. Shortell University of California, Berkeley

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