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Medicine

D-Index
102
Citations
52835
World Ranking
7527
National Ranking
3928

Overview

Tom Mikkelsen is affiliated with the Henry Ford Health System in the United States. Their research primarily focuses on Medicine, with significant contributions to Biochemistry, Genetics, and Molecular Biology.

Their work covers several subfields of study, including:

  • Genetics
  • Molecular Biology
  • Oncology
  • Cancer Research
  • Pulmonary and Respiratory Medicine

The main topics addressed in their research include:

  • Glioma Diagnosis and Treatment
  • Cancer Genomics and Diagnostics
  • Brain Metastases and Treatment
  • Cancer Cells and Metastasis
  • Radiomics and Machine Learning in Medical Imaging
  • Statistical Methods in Clinical Trials
  • Epigenetics and DNA Methylation

The scientist has published numerous papers in well-known academic venues. Frequent publication venues include:

  • Neuro-Oncology
  • Journal of Clinical Oncology
  • UNC Libraries
  • Journal of Neuro-Oncology
  • Neurosurgery

Among recent papers authored or coauthored by Tom Mikkelsen are:

  • Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma, 2022, JAMA Oncology
  • Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma, 2023, Journal of Clinical Oncology
  • A serum-based DNA methylation assay provides accurate detection of glioma, 2021, Neuro-Oncology
  • A phase II study of dose-dense temozolomide and lapatinib for recurrent low-grade and anaplastic supratentorial, infratentorial, and spinal cord ependymoma, 2020, Neuro-Oncology
  • Radiomics for precision medicine in glioblastoma, 2022, Journal of Neuro-Oncology

Tom Mikkelsen frequently collaborates with several coauthors, including:

  • Tobias Walbert
  • Ana C. deCarvalho
  • Patrick Y. Wen
  • Laila Poisson
  • Houtan Noushmehr

Best Publications

  • Comprehensive genomic characterization defines human glioblastoma genes and core pathways

    Roger McLendon;Allan Friedman;Darrell Bigner;Erwin G. Van Meir

  • The Somatic Genomic Landscape of Glioblastoma

    Cameron W. Brennan;Roel G W Verhaak;Aaron McKenna;Benito Campos

  • The Immune Landscape of Cancer

    Vésteinn Thorsson;David L Gibbs;Scott D Brown;Denise Wolf

  • Updated Response Assessment Criteria for High-Grade Gliomas: Response Assessment in Neuro-Oncology Working Group

    Patrick Y. Wen;David R. Macdonald;David A. Reardon;Timothy F. Cloughesy

  • Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

    Daniel J. Brat;Roel G.W. Verhaak;Kenneth D. Aldape;W. K.Alfred Yung

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma

    Henry S. Friedman;Michael D. Prados;Patrick Y. Wen;Tom Mikkelsen

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Comprehensive Characterization of Cancer Driver Genes and Mutations.

    Matthew H Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.

    Dominik Sturm;Hendrik Witt;Hendrik Witt;Volker Hovestadt;Dong Anh Khuong-Quang

  • Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.

    Michele Ceccarelli;Floris P Barthel;Tathiane M Malta;Thais S Sabedot

  • Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.

    Qianghu Wang;Baoli Hu;Xin Hu;Xin Hu;Hoon Kim

  • New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

    Dominik Sturm;Dominik Sturm;Brent A. Orr;Umut H. Toprak;Volker Hovestadt

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain

    Lixin Sun;Ai Min Hui;Qin Su;Alexander Vortmeyer

  • Clonal expansion of p53 mutant cells is associated with brain tumour progression

    David Sidransky;Tom Mikkelsen;Karl Schwechheimer;Mark L. Rosenblum

  • Pathogenic Germline Variants in 10,389 Adult Cancers

    Kuan-Lin Huang;R Jay Mashl;Yige Wu;Deborah I Ritter

  • Transforming fusions of FGFR and TACC genes in human glioblastoma

    Devendra Singh;Joseph Minhow Chan;Pietro Zoppoli;Francesco Niola;Francesco Niola

  • Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response

    Nicholas J. Szerlip;Alicia Pedraza;Debyani Chakravarty;Mohammad Azim

  • The somatic genomic landscape of glioblastoma

    Cameron W. Brennan;Roel G. W. Verhaak;Aaron Mckenna;Benito Campos

Frequent Co-Authors

Timothy F. Cloughesy
Timothy F. Cloughesy University of California, Los Angeles
Mark L. Rosenblum
Mark L. Rosenblum Henry Ford Health System
Michael D. Prados
Michael D. Prados University of California, San Francisco
Patrick Y. Wen
Patrick Y. Wen Harvard University
Hamid Soltanian-Zadeh
Hamid Soltanian-Zadeh University of Tehran
Jeffrey J. Olson
Jeffrey J. Olson Emory University
Stuart A. Grossman
Stuart A. Grossman Johns Hopkins University
Houtan Noushmehr
Houtan Noushmehr Henry Ford Health System
Michael A. Vogelbaum
Michael A. Vogelbaum Cleveland Clinic
Roel G.W. Verhaak
Roel G.W. Verhaak The Jackson Laboratory

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