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Molecular Biology

D-Index
57
Citations
14197
World Ranking
2139
National Ranking
1063

Research.com Recognitions

  • 2006 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Timothy W. Nilsen is affiliated with Case Western Reserve University in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine. The scientist's work is focused on several subfields including hepatology, molecular biology, and genetics.

The main topics covered by Nilsen's research include:

  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • Bacterial genetics and biotechnology
  • Hepatitis viruses studies and epidemiology
  • Liver disease and transplantation
  • Hepatitis C virus research

Timothy W. Nilsen has contributed to research documented in the following publication venues:

  • RNA
  • Viruses

Some of the frequent co-authors associated with Nilsen's research include:

  • Venkat Gopalan
  • Ann M. Altman
  • Benjamin C. Stark
  • Sheldon I. Feinstein
  • R. K. Koski

Representative recent papers authored or co-authored by Nilsen include:

  • "Tribute to Sidney AltmanSIDNEY ALTMAN: AN EXEMPLARY SCIENTIST, TEACHER, AND FRIEND (1939-2022)SIDNEY ALTMAN'S GREATEST ACHIEVEMENTA SHORT HISTORY OF THE DISCOVERY OF THE ESSENTIAL RNA COMPONENT OF RNase PRECOLLECTIONS OF A GRADUATE STUDENT IN SIDNEY ALTMAN'S LABORATORYMEMORIES FROM THE EARLY YEARS OF THE SIDNEY ALTMAN LABORATORYTHE SPINACH CHLOROPLAST RNase P: THE FIRST PROTEIN-ONLY RNase P!SIDNEY ALTMAN: A BRIEF MEMOIRSIDNEY ALTMAN: IN MEMORIAM ET GRATITUDINEMTALES OF THE UNEXPECTED IN SIDNEY ALTMAN'S LABORATORYTO CLEAVE OR NOT TO CLEAVE, THAT IS THE QUESTIONSIDNEY ALTMAN: CHALLENGING AUTHORITY AND BEING AN ERUDITE SCHOLARTRIBUTE TO MY BELOVED MENTOR, SIDNEY ALTMANHAVING A MENTOR FOR AN ERAIN MEMORY OF PROFESSOR SIDNEY ALTMAN: INSPIRING PEOPLE TO THE FULLHALF A CENTURY WITH SIDNEY ALTMANRECOLLECTIONS OF MY FRIENDSHIP WITH SID ALTMANPERSONAL MEMORIES OF SIDNEY ALTMANA REMARKABLE CATALYSTREMEMBERING SIDNEY ALTMANSIDNEY ALTMAN-A SCIENTIFIC ODYSSEYSID ALTMAN: FRIEND, COLLEAGUE, AND GODFATHERSIDNEY ALTMAN-A REMEMBRANCERECOLLECTIONS OF MY SCIENTIFIC INTERACTIONS WITH SIDNEY ALTMANSIDNEY ALTMAN'S TIES TO CHINATARGETING RNA TO FIGHT ANTIBIOTIC-RESISTANT BACTERIASIDNEY ALTMAN: IN HIS OWN WORDS" (2022), published in RNA
  • "Cellular and Humoral Immune Profiles After Hepatitis E Vaccination and Infection" (2025), published in Viruses

Among professional recognitions, Nilsen was awarded the distinction of Fellow of the American Association for the Advancement of Science (AAAS) in 2006.

Best Publications

  • Expansion of the eukaryotic proteome by alternative splicing

    Timothy W. Nilsen;Brenton R. Graveley

  • Purification of RNA using TRIzol (TRI reagent).

    Donald C. Rio;Manuel Ares;Gregory J. Hannon;Timothy W. Nilsen

  • Mechanisms of microRNA-mediated gene regulation in animal cells

    Timothy W. Nilsen

  • Functional recognition of the 3' splice site AG by the splicing factor U2AF35.

    Shaoping Wu;Charles M. Romfo;Timothy W. Nilsen;Michael R. Green

  • The spliceosome: the most complex macromolecular machine in the cell?

    Timothy W. Nilsen

  • Evidence that microRNAs are associated with translating messenger RNAs in human cells

    Patricia A Maroney;Yang Yu;Jesse Fisher;Timothy W Nilsen

  • Protein displacement by DExH/D "RNA helicases" without duplex unwinding.

    Margaret E. Fairman;Patricia A. Maroney;Wen Wang;Heath A. Bowers

  • RNA-RNA INTERACTIONS IN THE SPLICEOSOME : UNRAVELING THE TIES THAT BIND

    Timothy W. Nilsen

  • c-erbB activation in ALV-induced erythroblastosis: novel RNA processing and promoter insertion result in expression of an amino-truncated EGF receptor.

    Timothy W. Nilsen;Patricia A. Maroney;Raymond G. Goodwin;Fritz M. Rottman

  • Trans-Splicing of Nematode Premessenger RNA

    Timothy W. Nilsen

  • Structure and transcription of a human gene for H1 RNA, the RNA component of human RNase P

    Madeline Baer;Timothy W. Nilsen;Christine Costigan;Sidney Altman

  • Mapping of N6-methyladenosine residues in bovine prolactin mRNA.

    Sarah Horowitz;Amikam Horowitz;Timothy W. Nilsen;Theodore W. Munns

  • Trans splicing of nematode pre-messenger RNA in vitro.

    Gregory J. Hannon;Patricia A. Maroney;John A. Denker;Timothy W. Nilsen

  • RNA-RNA Interactions in Nuclear Pre-mRNA Splicing

    Timothy W. Nilsen

  • Functional Recognition of the 5′ Splice Site by U4/U6.U5 tri-snRNP Defines a Novel ATP-Dependent Step in Early Spliceosome Assembly

    Patricia A. Maroney;Charles M. Romfo;Timothy W. Nilsen

  • A novel class of microRNA-recognition elements that function only within open reading frames.

    Kai Zhang;Xiaorong Zhang;Zhiqiang Cai;Jie Zhou

  • Dynamic Regulation of Alternative Splicing by Silencers that Modulate 5′ Splice Site Competition

    Yang Yu;Patricia A. Maroney;John A. Denker;Xiang H.-F. Zhang

  • Kaposi's Sarcoma-Associated Herpesvirus Utilizes and Manipulates RNA N6-Adenosine Methylation To Promote Lytic Replication

    Fengchun Ye;E. Ricky Chen;Timothy W. Nilsen

  • A rapid, quantitative assay for direct detection of microRNAs and other small RNAs using splinted ligation.

    Patricia A. Maroney;Sangpen Chamnongpol;Frédéric Souret;Timothy W. Nilsen

  • Mechanisms of microRNA-mediated gene regulation

    Timothy W. Nilsen

Frequent Co-Authors

Gregory J. Hannon
Gregory J. Hannon University of Cambridge
Manuel Ares
Manuel Ares University of California, Santa Cruz
Fritz Rottman
Fritz Rottman Michigan State University
Eckhard Jankowsky
Eckhard Jankowsky Case Western Reserve University
Hsing Jien Kung
Hsing Jien Kung Taipei Medical University
Xiang-Dong Fu
Xiang-Dong Fu Westlake University
Richard M. Ransohoff
Richard M. Ransohoff Harvard University
James W. Kazura
James W. Kazura Case Western Reserve University
Edward Darzynkiewicz
Edward Darzynkiewicz University of Warsaw
Reinhard Lührmann
Reinhard Lührmann Max Planck Society

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