World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
12742
World Ranking
15488
National Ranking
6463

Overview

Stephen J. Lockett is affiliated with the National Institutes of Health in the United States. Their research spans multiple fields of study primarily focused on medicine and biochemistry, genetics, and molecular biology. Within these broad fields, their work is deeply involved in molecular biology, oncology, immunology, pharmacology, and pulmonary and respiratory medicine.

Their research topics include inflammatory mediators and NSAID effects, immune cells in cancer, cancer immunotherapy and biomarkers, cancer cells and metastasis, cancer hypoxia and metabolism, estrogen and related hormone effects, and chemokine receptors and signaling. These areas illustrate a focus on the molecular and cellular processes underlying cancer and immune response mechanisms.

Stephen J. Lockett has frequently published in notable venues, including bioRxiv (Cold Spring Harbor Laboratory), Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, Cancer Research, the British Journal of Cancer, and the Proceedings of the National Academy of Sciences. Their collaboration network features several frequent co-authors, including David A. Wink, Lisa A. Ridnour, David A. Scheiblin, William F. Heinz, and Robert Y.S. Cheng.

Notable recent papers authored or co-authored by Lockett encompass the following:

  • Impacts of combining anti-PD-L1 immunotherapy and radiotherapy on the tumour immune microenvironment in a murine prostate cancer model, 2020, British Journal of Cancer
  • Collective cancer cell invasion requires RNA accumulation at the invasive front, 2020, Proceedings of the National Academy of Sciences
  • Nitric Oxide Modulates Metabolic Processes in the Tumor Immune Microenvironment, 2021, International Journal of Molecular Sciences
  • Id1 and Id3 Maintain Steady-State Hematopoiesis by Promoting Sinusoidal Endothelial Cell Survival and Regeneration, 2020, Cell Reports
  • Synchronous RNA conformational changes trigger ordered phase transitions in crystals, 2021, Nature Communications

Best Publications

  • Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging.

    Ana Krtolica;Simona Parrinello;Stephen Lockett;Pierre-Yves Desprez

  • Automatic and Quantitative Measurement of Protein-Protein Colocalization in Live Cells

    Sylvain V. Costes;Dirk Daelemans;Edward H. Cho;Zachary Dobbin

  • Phosphatidylinositol (4,5) bisphosphate regulates HIV-1 Gag targeting to the plasma membrane.

    Akira Ono;Sherimay D. Ablan;Stephen J. Lockett;Kunio Nagashima

  • The Transformation Suppressor Pdcd4 Is a Novel Eukaryotic Translation Initiation Factor 4A Binding Protein That Inhibits Translation

    Hsin Sheng Yang;Aaron P. Jansen;Anton A. Komar;Xiaojing Zheng

  • Inhibition of Metastatic Outgrowth from Single Dormant Tumor Cells by Targeting the Cytoskeleton

    Dalit Barkan;Hynda Kleinman;Justin L. Simmons;Holly Asmussen

  • In situ analyses of genome instability in breast cancer

    Koei Chin;Carlos Ortiz de Solorzano;David Knowles;Arthur Jones

  • Activation of Toll-like Receptor 2 on Microglia Promotes Cell Uptake of Alzheimer Disease-associated Amyloid β Peptide

    Keqiang Chen;Pablo Iribarren;Jinyue Hu;Jianhong Chen

  • High efficiency of HIV-1 genomic RNA packaging and heterozygote formation revealed by single virion analysis.

    Jianbo Chen;Olga Nikolaitchik;Jatinder Singh;Andrew Wright

  • Lipid rafts and the local density of ErbB proteins influence the biological role of homo- and heteroassociations of ErbB2

    Peter Nagy;Peter Nagy;György Vereb;Zsolt Sebestyén;Gábor Horváth

  • Analysis of the extracellular matrix vesicle proteome in mineralizing osteoblasts.

    Zhen Xiao;Corinne E. Camalier;Kunio Nagashima;King C. Chan

  • Segmentation of confocal microscope images of cell nuclei in thick tissue sections

    C Ortiz de Solórzano;E García Rodriguez;A Jones;D Pinkel

  • Human T-cell leukemia virus type 1 p8 protein increases cellular conduits and virus transmission

    Nancy Van Prooyen;Heather Gold;Vibeke Andresen;Owen Schwartz

  • Segmentation of nuclei and cells using membrane related protein markers.

    C. Ortiz De Solorzano;R. Malladi;S. A. Lelièvre;S. J. Lockett

  • Fullerenol cytotoxicity in kidney cells is associated with cytoskeleton disruption, autophagic vacuole accumulation, and mitochondrial dysfunction.

    Denise N. Johnson-Lyles;Kimberly Peifley;Stephen Lockett;Barry W. Neun

  • Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3.

    Evgenij Evdokimov;Prashant Sharma;Stephen J. Lockett;Margaret Lualdi

  • Structural protein 4.1 in the nucleus of human cells: dynamic rearrangements during cell division.

    Sharon Wald Krauss;Carolyn A. Larabell;Stephen Lockett;Philippe Gascard

  • Coherent anti-stokes Raman scattering microscopy: a biological review.

    Luis G. Rodriguez;Stephen J. Lockett;Gary R. Holtom

  • Disease-specific gene repositioning in breast cancer

    Karen J. Meaburn;Prabhakar R. Gudla;Sameena Khan;Stephen J. Lockett

  • Identification of neutrophil granule protein cathepsin G as a novel chemotactic agonist for the G protein-coupled formyl peptide receptor.

    Ronghua Sun;Pablo Iribarren;Ning Zhang;Ye Zhou

  • Human CD8+ T Cells Store RANTES in a Unique Secretory Compartment and Release It Rapidly after TcR Stimulation

    Marta Catalfamo;Tatiana Karpova;James McNally;Sylvain V. Costes

Frequent Co-Authors

Joe W. Gray
Joe W. Gray Oregon Health & Science University
Brian Herman
Brian Herman The University of Texas Health Science Center at San Antonio
David A. Wink
David A. Wink National Institutes of Health
Kunio Nagashima
Kunio Nagashima National Institutes of Health
Ji Ming Wang
Ji Ming Wang National Institutes of Health
Daniel W. McVicar
Daniel W. McVicar National Institutes of Health
Tom Misteli
Tom Misteli National Institutes of Health
Ken Jacobson
Ken Jacobson University of North Carolina at Chapel Hill
Daniel Pinkel
Daniel Pinkel University of California, San Francisco
Wanghua Gong
Wanghua Gong Leidos (United States)

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Stephen J. Lockett

Trending Scientists

Recently Published Articles