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Immunology

D-Index
51
Citations
19718
World Ranking
4102
National Ranking
1869

Overview

Saurabh Mehandru is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research spans several areas within medicine and biochemistry, genetics, and molecular biology, with a particular focus on genetics, immunology, epidemiology, infectious diseases, and surgery.

The scientist has contributed significantly to the understanding of inflammatory bowel disease and COVID-19, concentrating on immune cell function and the long-term effects of viral infections. Their work engages heavily with topics including:

  • Inflammatory Bowel Disease
  • Microscopic Colitis
  • Immune Cell Function and Interaction
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • SARS-CoV-2 and COVID-19 Research
  • T-cell and B-cell Immunology

Among their recent publications, the following papers stand out:

  • "Pathological sequelae of long-haul COVID" (2022), published in Nature Immunology
  • "The intestinal barrier, an arbitrator turned provocateur in IBD" (2020), published in Nature Reviews Gastroenterology & Hepatology

Saurabh Mehandru has co-authored works with several other researchers, including:

  • Jean-Frédéric Colombel
  • Alexandra E. Livanos
  • Divya Jha
  • Michael Tankelevich
  • Francesca Cossarini

The scientist frequently publishes in several specialized venues, with multiple publications in:

  • Gastroenterology
  • Journal of Crohn's and Colitis
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Reviews Gastroenterology & Hepatology
  • Inflammatory Bowel Diseases

Their body of work incorporates over 180 publications in medicine and 73 in biochemistry, genetics, and molecular biology. Their research contributions have been recognized and cited across various high-impact journals focusing on health conditions related to inflammatory peptides and viral infections.

Best Publications

  • Evolution of antibody immunity to SARS-CoV-2.

    Christian Gaebler;Zijun Wang;Julio C. C. Lorenzi;Frauke Muecksch

  • Immunology of COVID-19: Current State of the Science.

    Nicolas Vabret;Graham J. Britton;Conor Gruber;Samarth Hegde

  • Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract.

    Saurabh Mehandru;Michael A. Poles;Michael A. Poles;Klara Tenner-Racz;Amir Horowitz;Amir Horowitz

  • Lack of mucosal immune reconstitution during prolonged treatment of acute and early HIV-1 infection.

    Saurabh Mehandru;Michael A Poles;Michael A Poles;Klara Tenner-Racz;Patrick Jean-Pierre

  • DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypes

    Leonia Bozzacco;Christine Trumpfheller;Frederick P. Siegal;Saurabh Mehandru

  • The intestinal barrier, an arbitrator turned provocateur in IBD.

    Saurabh Mehandru;Jean-Frederic Colombel

  • Mechanisms of Gastrointestinal CD4+ T-Cell Depletion during Acute and Early Human Immunodeficiency Virus Type 1 Infection

    Saurabh Mehandru;Michael A. Poles;Michael A. Poles;Klara Tenner-Racz;Victoria Manuelli

  • Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity

    Unknown

  • Flt3 Signaling-Dependent Dendritic Cells Protect against Atherosclerosis

    Jae Hoon Choi;Cheolho Cheong;Durga B. Dandamudi;Chae Gyu Park

  • Tracking the prevalence of transmitted antiretroviral drug-resistant HIV-1: a decade of experience.

    Anita Shet;Leslie Berry;Hiroshi Mohri;Saurabh Mehandru

  • Infection with multidrug resistant, dual-tropic HIV-1 and rapid progression to AIDS: a case report.

    Martin Markowitz;Hiroshi Mohri;Saurabh Mehandru;Anita Shet

  • Infants born to mothers with IBD present with altered gut microbiome that transfers abnormalities of the adaptive immune system to germ-free mice.

    Joana Torres;Jianzhong Hu;Akihiro Seki;Caroline Eisele

  • Fecal IgA Levels Are Determined by Strain-Level Differences in Bacteroides ovatus and Are Modifiable by Gut Microbiota Manipulation.

    Chao Yang;Ilaria Mogno;Eduardo J. Contijoch;Joshua N. Borgerding

  • Coronavirus 2019 and People Living With Human Immunodeficiency Virus: Outcomes for Hospitalized Patients in New York City

    Keith Sigel;Talia Swartz;Eddye Golden;Ishan Paranjpe

  • Human Secretory IgM Emerges from Plasma Cells Clonally Related to Gut Memory B Cells and Targets Highly Diverse Commensals

    Giuliana Magri;Laura Comerma;Marc Pybus;Jordi Sintes

  • Adjunctive passive immunotherapy in human immunodeficiency virus type 1-infected individuals treated with antiviral therapy during acute and early infection.

    Saurabh Mehandru;Brigitta Vcelar;Terri Wrin;Gabriela Stiegler

  • Absence of HIV-1 evolution in the gut-associated lymphoid tissue from patients on combination antiviral therapy initiated during primary infection.

    Teresa H. Evering;Saurabh Mehandru;Paul Racz;Klara Tenner-Racz

  • Gastrointestinal Disorders Associated with Common Variable Immune Deficiency (CVID) and Chronic Granulomatous Disease (CGD).

    Mathieu Uzzan;Huaibin M. Ko;Saurabh Mehandru;Charlotte Cunningham-Rundles

  • Evolution of Antibody Immunity to SARS-CoV-2

    Christian Gaebler;Zijun Wang;Julio C C Lorenzi;Frauke Muecksch

  • Intestinal Host Response to SARS-CoV-2 Infection and COVID-19 Outcomes in Patients With Gastrointestinal Symptoms.

    Alexandra E. Livanos;Divya Jha;Francesca Cossarini;Ana S. Gonzalez-Reiche

  • Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract.

    Darren Ruane;Lucas Brane;Bernardo Sgarbi Reis;Cheolho Cheong;Cheolho Cheong

Frequent Co-Authors

Jean-Frederic Colombel
Jean-Frederic Colombel Icahn School of Medicine at Mount Sinai
Martin Markowitz
Martin Markowitz Rockefeller University
Marla Dubinsky
Marla Dubinsky Icahn School of Medicine at Mount Sinai
Andrea Cerutti
Andrea Cerutti Icahn School of Medicine at Mount Sinai
Judy H. Cho
Judy H. Cho Icahn School of Medicine at Mount Sinai
Miriam Merad
Miriam Merad Icahn School of Medicine at Mount Sinai
Ralph M. Steinman
Ralph M. Steinman Rockefeller University
Mayte Suárez-Fariñas
Mayte Suárez-Fariñas Icahn School of Medicine at Mount Sinai
Klara Tenner-Racz
Klara Tenner-Racz Bernhard Nocht Institute for Tropical Medicine

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