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Medicine

D-Index
96
Citations
29731
World Ranking
9779
National Ranking
951

Overview

Ruth J. Muschel is affiliated with the University of Oxford in the United Kingdom. Their research spans multiple fields, with a focus on medicine and biochemistry, genetics, and molecular biology. Within these broad areas, their work predominantly covers oncology, molecular biology, and immunology, alongside contributions to pulmonary and respiratory medicine and cancer research.

Their research topics often include cancer, hypoxia, and metabolism; cancer immunotherapy and biomarkers; immunotherapy and immune responses; prostate cancer treatment and research; mathematical biology related to tumor growth; effects of radiation exposure; and immune cells in cancer.

Muschel has co-authored multiple publications with a range of colleagues. Frequent co-authors include Boštjan Markelc, Jakob Kaeppler, Jianzhou Chen, Helen M. Byrne, and Bernadette J. Stolz.

Publications appear regularly in respected venues, including bioRxiv (Cold Spring Harbor Laboratory), British Journal of Cancer, Cancer Research, Zenodo (CERN European Organization for Nuclear Research), and Cancer & Metabolism.

Some of the recent papers associated with their name include:

  • Liver metastases, 2021, Nature Reviews Disease Primers
  • Irradiation at Ultra-High (FLASH) Dose Rates Reduces Acute Normal Tissue Toxicity in the Mouse Gastrointestinal System, 2021, International Journal of Radiation Oncology*Biology*Physics
  • FGF2 alters macrophage polarization, tumour immunity and growth and can be targeted during radiotherapy, 2020, Nature Communications
  • Platelets and Metastasis: New Implications of an Old Interplay, 2020, Frontiers in Oncology
  • Impacts of combining anti-PD-L1 immunotherapy and radiotherapy on the tumour immune microenvironment in a murine prostate cancer model, 2020, British Journal of Cancer

Best Publications

  • KILLER/DR5 is a DNA damage–inducible p53–regulated death receptor gene

    G. S. Wu;T. F. Burns;E. R. McDonald;W. Jiang

  • Correction: Corrigendum: Cancer cells that survive radiation therapy acquire HIF-1 activity and translocate toward tumour blood vessels

    Hiroshi Harada;Masahiro Inoue;Satoshi Itasaka;Kiichi Hirota

  • Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: a new model for metastasis.

    A B Al-Mehdi;K Tozawa;A B Fisher;L Shientag

  • A Distinct Macrophage Population Mediates Metastatic Breast Cancer Cell Extravasation, Establishment and Growth

    Binzhi Qian;Yan Deng;Jae Hong Im;Ruth J. Muschel

  • Cancer stem cells from colorectal cancer-derived cell lines

    Trevor M. Yeung;Shaan C. Gandhi;Jennifer L. Wilding;Ruth Muschel

  • miR-182-Mediated Downregulation of BRCA1 Impacts DNA Repair and Sensitivity to PARP Inhibitors

    Patryk Moskwa;Francesca M. Buffa;Yunfeng Pan;Rohit Panchakshari

  • Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells.

    Eric J. Bernhard;Stephen B. Gruber;Ruth J. Muschel

  • Targeting the CCL2-CCR2 signaling axis in cancer metastasis.

    Su Yin Lim;Arseniy E. Yuzhalin;Alex N. Gordon-Weeks;Ruth J. Muschel

  • Local recurrence in head and neck cancer: relationship to radiation resistance and signal transduction.

    Anjali K Gupta;W Gillies McKenna;Charles N Weber;Michael D Feldman

  • Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation

    E Fokas;R Prevo;J R Pollard;P M Reaper

  • On the dual roles and polarized phenotypes of neutrophils in tumor development and progression.

    H Piccard;R J Muschel;Ghislain Opdenakker

  • The molecular basis for cell cycle delays following ionizing radiation: a review.

    A Maity;W G McKenna;R J Muschel

  • Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice

    Ana M. Gil-Bernabé;Špela Ferjančič;Monika Tlalka;Lei Zhao

  • The Vascular Basement Membrane as “Soil” in Brain Metastasis

    W. Shawn Carbonell;Olaf Ansorge;Nicola Sibson;Ruth Muschel

  • Coagulation facilitates tumor cell spreading in the pulmonary vasculature during early metastatic colony formation.

    Jae Hong Im;Weili Fu;Hui Wang;Sujata K. Bhatia

  • Apoptosis: an early event in metastatic inefficiency.

    Christopher W. Wong;Andrea Lee;Lisa Shientag;Jong Yu

  • Mesenchymal Stem Cells Prevent the Rejection of Fully Allogenic Islet Grafts by the Immunosuppressive Activity of Matrix Metalloproteinase-2 and -9

    Yunchuan Ding;Danmei Xu;Gang Feng;Andrew Bushell

  • The Ras Radiation Resistance Pathway

    Anjali K. Gupta;Vincent J. Bakanauskas;George J. Cerniglia;Yi Cheng

  • Proteases, extracellular matrix, and cancer: a workshop of the path B study section.

    Yves A. DeClerck;Arthur M. Mercurio;M. Sharon Stack;Harold A. Chapman

  • BRCA1 Effects on the Cell Cycle and the DNA Damage Response Are Linked to Altered Gene Expression

    Timothy K. MacLachlan;Kumaravel Somasundaram;Magda Sgagias;Yelena Shifman

Frequent Co-Authors

Thomas Brunner
Thomas Brunner University of Konstanz
Stephen M. Hahn
Stephen M. Hahn The University of Texas Health Science Center at Houston
Nicola R. Sibson
Nicola R. Sibson University of Oxford
Ester M. Hammond
Ester M. Hammond University of Oxford
adrian l harris
adrian l harris University of Oxford
Rosemarie Mick
Rosemarie Mick University of Pennsylvania
Jeffrey W. Pollard
Jeffrey W. Pollard University of Edinburgh
Andrew D. Hamilton
Andrew D. Hamilton New York University
Wafik S. El-Deiry
Wafik S. El-Deiry Brown University
Daniel C. Anthony
Daniel C. Anthony University of Oxford

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