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Medicine

D-Index
96
Citations
107171
World Ranking
9447
National Ranking
4874

Overview

P. Andrew Futreal is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research spans multiple fields within medicine and biological sciences, primarily focusing on oncology, molecular biology, and cancer research.

Their main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broader fields, their subfields of study encompass:

  • Oncology
  • Molecular Biology
  • Cancer Research
  • Pulmonary and Respiratory Medicine
  • Immunology

The main topics of their work reflect a concentration on cancer and immunology, including:

  • Cancer Genomics and Diagnostics
  • Cancer Immunotherapy and Biomarkers
  • Single-cell and spatial transcriptomics
  • Acute Myeloid Leukemia Research
  • CAR-T cell therapy research
  • Immunotherapy and Immune Responses
  • Immune Cell Function and Interaction

Their recent notable publications include:

  • "Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response" (2021, Science)
  • "Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial" (2021, Nature Medicine)
  • "Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade" (2021, Nature Medicine)
  • "Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance" (2023, Nature Medicine)
  • "Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics" (2020, Nature Communications)

Frequent co-authors in their body of work include:

  • Jianhua Zhang
  • Ignacio I. Wistuba
  • Xingzhi Song
  • Latasha Little
  • Linghua Wang

They have published extensively in several prominent scientific venues, such as:

  • Cancer Research
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Blood
  • Clinical Cancer Research

Best Publications

  • Mutations of the BRAF gene in human cancer

    Helen Davies;Graham R. Bignell;Charles Cox;Philip Stephens

  • Signatures of mutational processes in human cancer

    Ludmil B. Alexandrov;Serena Nik-Zainal;Serena Nik-Zainal;David C. Wedge;Samuel A. J. R. Aparicio

  • A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

    Yoshio Miki;Jeff Swensen;Donna Shattuck-Eidens;P. Andrew Futreal

  • The cancer genome

    Michael R. Stratton;Michael R. Stratton;Peter J. Campbell;Peter J. Campbell;P. Andrew Futreal

  • A census of human cancer genes

    P. Andrew Futreal;Lachlan Coin;Mhairi Marshall;Thomas Down

  • Patterns of somatic mutation in human cancer genomes

    Christopher Greenman;Philip Stephens;Raffaella Smith;Gillian L. Dalgliesh

  • Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells

    Wanjuan Yang;Jorge Soares;Patricia Greninger;Elena J. Edelman

  • Systematic identification of genomic markers of drug sensitivity in cancer cells

    Mathew J. Garnett;Elena J. Edelman;Sonja J. Heidorn;Christopher Greenman;Christopher Greenman

  • COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer.

    Simon A. Forbes;Nidhi Bindal;Sally Bamford;Charlotte Cole

  • Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

    Philip J. Stephens;Chris D. Greenman;Beiyuan Fu;Fengtang Yang

  • International network of cancer genome projects

    Thomas J. Hudson;Thomas J. Hudson;Warwick Anderson;Axel Aretz;Anna D. Barker

  • Landscape of somatic mutations in 560 breast cancer whole-genome sequences

    Serena Nik-Zainal;Serena Nik-Zainal;Helen Davies;Johan Staaf;Manasa Ramakrishna

  • Mutational Processes Molding the Genomes of 21 Breast Cancers

    Serena Nik-Zainal;Ludmil B. Alexandrov;David C. Wedge;Peter Van Loo;Peter Van Loo;Peter Van Loo

  • A comprehensive catalogue of somatic mutations from a human cancer genome

    Erin D. Pleasance;R. Keira Cheetham;Philip J. Stephens;David J. Mcbride

  • The landscape of cancer genes and mutational processes in breast cancer

    Philip J. Stephens;Patrick S. Tarpey;Helen Davies;Peter Van Loo;Peter Van Loo

  • Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

    Xose S. Puente;Magda Pinyol;Víctor Quesada;Laura Conde

  • Exome sequencing identifies frequent mutation of the SWI/SNF Complex Gene PBRM1 in renal carcinoma

    Ignacio Varela;Patrick Tarpey;Keiran Raine;Dachuan Huang

  • BRCA1 mutations in primary breast and ovarian carcinomas

    P. Andrew Futreal;Qingyun Liu;Donna Shattuck-Eidens;Charles Cochran

  • JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis.

    Linda M. Scott;Wei Tong;Ross L. Levine;Mike A. Scott

  • The Life History of 21 Breast Cancers

    Serena Nik-Zainal;Peter Van Loo;Peter Van Loo;Peter Van Loo;David C. Wedge;Ludmil B. Alexandrov

Frequent Co-Authors

Mark H. Skolnick
Mark H. Skolnick Myriad Genetics (Germany)
Adrienne M. Flanagan
Adrienne M. Flanagan University College London
Jeffrey R. Marks
Jeffrey R. Marks Duke University
Peter J. Campbell
Peter J. Campbell Wellcome Sanger Institute
J. Carl Barrett
J. Carl Barrett AstraZeneca (United Kingdom)
Michael R. Stratton
Michael R. Stratton Wellcome Sanger Institute
Ultan McDermott
Ultan McDermott AstraZeneca (United Kingdom)
Sean V. Tavtigian
Sean V. Tavtigian University of Utah
Jon W. Teague
Jon W. Teague Wellcome Sanger Institute
Inigo Martincorena
Inigo Martincorena Wellcome Sanger Institute

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