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Immunology

D-Index
53
Citations
8618
World Ranking
4003
National Ranking
353

Overview

Lindy G. Durrant is affiliated with the University of Nottingham in the United Kingdom. Their research spans multiple intersecting fields within biomedical sciences, predominantly focusing on medicine, immunology and microbiology, and biochemistry, genetics, and molecular biology. The scientist's work is often situated within subfields such as immunology, oncology, molecular biology, genetics, and cell biology.

Their scholarly contributions include research on cancer immunotherapy and immune responses as well as glycosylation and glycoproteins. Specific topics explored by Durrant include immunotherapy and immune responses, cancer immunotherapy and biomarkers, glycosylation and glycoproteins research, CAR-T cell therapy research, peptidase inhibition and analysis, vaccines and immunoinformatics approaches, and RNA interference and gene delivery.

Frequent co-authors collaborating with Durrant are:

  • Victoria A. Brentville
  • Mireille Vankemmelbeke
  • Samantha Paston
  • Peter Symonds
  • Rachael L. Metheringham

Durrant has published numerous papers in prominent scientific journals. Frequent publication venues include:

  • Frontiers in Immunology
  • Journal for ImmunoTherapy of Cancer
  • Cancer Research
  • Scientific Reports
  • Cancers

Selected recent papers authored or co-authored by Lindy G. Durrant include:

  • Cancer Vaccines, Adjuvants, and Delivery Systems, 2021, Frontiers in Immunology
  • Immune Escape in Glioblastoma Multiforme and the Adaptation of Immunotherapies for Treatment, 2020, Frontiers in Immunology
  • Combination vaccine based on citrullinated vimentin and enolase peptides induces potent CD4-mediated anti-tumor responses, 2020, Journal for ImmunoTherapy of Cancer
  • Post-translational modifications such as citrullination are excellent targets for cancer therapy, 2020, Seminars in Immunology
  • Native/citrullinated LL37-specific T-cells help autoantibody production in Systemic Lupus Erythematosus, 2020, Scientific Reports

Best Publications

  • Immunosurveillance is active in colorectal cancer as downregulation but not complete loss of MHC class I expression correlates with a poor prognosis.

    Nicholas F.S. Watson;Judith M. Ramage;Zahra Madjd;Ian Spendlove

  • Human Leukocyte Antigen Class I, MHC Class I Chain-Related Molecule A, and CD8+/Regulatory T-Cell Ratio: Which Variable Determines Survival of Cervical Cancer Patients?

    Ekaterina S. Jordanova;Arko Gorter;Ouissam Ayachi;Frans Prins

  • Intratumoral T cell infiltration, MHC class I and STAT1 as biomarkers of good prognosis in colorectal cancer

    Jonathan A D Simpson;Ahmad Al-Attar;Nicholas F S Watson;John H Scholefield

  • NKG2D Ligand Expression in Human Colorectal Cancer Reveals Associations with Prognosis and Evidence for Immunoediting

    Roger W. McGilvray;Robert A. Eagle;Nicholas F.S. Watson;Ahmad Al-Attar

  • Expression of the stress-related MHC class I chain-related protein MICA is an indicator of good prognosis in colorectal cancer patients

    Nicholas F.S. Watson;Nicholas F.S. Watson;Ian Spendlove;Zahra Madjd;Roger McGilvray

  • Defining the critical hurdles in cancer immunotherapy

    Bernard A. Fox;Bernard A. Fox;Dolores J. Schendel;Lisa H. Butterfield;Steinar Aamdal

  • Total loss of MHC class I is an independent indicator of good prognosis in breast cancer

    Zahra Madjd;Ian Spendlove;Sarah E. Pinder;Ian O. Ellis

  • Cancer Vaccines, Adjuvants, and Delivery Systems.

    Samantha J. Paston;Victoria A. Brentville;Peter Symonds;Lindy G. Durrant

  • The in vitro growth response of primary human colorectal and gastric cancer cells to gastrin.

    S. A. Watson;L. G. Durrant;J. D. Crosbie;D. L. Morris

  • Vascular endothelial growth factor expression in ovarian cancer: a model for targeted use of novel therapies?

    Timothy J. Duncan;Ahmad Al-Attar;Phil Rolland;Ian V. Scott

  • Gastrin: growth enhancing effects on human gastric and colonic tumour cells.

    S Watson;L Durrant;D Morris

  • CD55 is over-expressed in the tumour environment

    L Li;I Spendlove;J Morgan;L G Durrant

  • The ubiquitin-binding protein p62 is expressed in breast cancers showing features of aggressive disease

    Phil Rolland;Zahra Madjd;Lindy Durrant;Ian O Ellis

  • Phase I study of monoclonal antibody-ricin A chain immunotoxin XomaZyme-791 in patients with metastatic colon cancer.

    V S Byers;R Rodvien;K Grant;L G Durrant

  • Enhanced expression of the complement regulatory protein CD55 predicts a poor prognosis in colorectal cancer patients

    L. G. Durrant;M. A. Chapman;D. J. Buckley;I. Spendlove

  • High expression of Lewis y/b antigens is associated with decreased survival in lymph node negative breast carcinomas.

    Zahra Madjd;Tina Parsons;Nicholas F S Watson;Ian Spendlove

  • Growth-promoting action of gastrin on human colonic and gastric tumour cells cultured in vitro.

    S. A. Watson;L. G. Durrant;D. L. Morris

  • The chemokine, CXCL12, is an independent predictor of poor survival in ovarian cancer.

    A Popple;L G Durrant;I Spendlove;P Rolland

  • Costimulation via CD55 on Human CD4 + T Cells Mediated by CD97

    Melania Capasso;Lindy G. Durrant;Martin Stacey;Siamon Gordon

  • Overexpression of FLIPL is an independent marker of poor prognosis in colorectal cancer patients.

    Gustave J. Ullenhag;Abhik Mukherjee;Nicholas F.S. Watson;Ahmad H. Al-Attar

Frequent Co-Authors

Robert W. Baldwin
Robert W. Baldwin University of Nottingham
Ian O. Ellis
Ian O. Ellis University of Nottingham
Uwe Aickelin
Uwe Aickelin University of Melbourne
David L. Morris
David L. Morris University of New South Wales
Sarah E Pinder
Sarah E Pinder King's College London
Robert C. Rees
Robert C. Rees Nottingham Trent University
Andrew R. Green
Andrew R. Green University of Nottingham
Christian H. Ottensmeier
Christian H. Ottensmeier University of Southampton
Guoping Qiu
Guoping Qiu University of Nottingham
Dileep N. Lobo
Dileep N. Lobo University of Nottingham

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