World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
48
Citations
10774
World Ranking
2669
National Ranking
74

Overview

Lijian Hui is affiliated with ShanghaiTech University in China, with a research focus primarily in Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans key subfields including Molecular Biology, Hepatology, Surgery, Immunology, and Epidemiology.

The main research topics covered by Hui include:

  • Liver physiology and pathology
  • Pancreatic function and diabetes
  • Organ transplantation techniques and outcomes
  • Liver disease diagnosis and treatment
  • Pluripotent stem cells research
  • Immune cells in cancer
  • RNA modifications and cancer

Hui has published extensively in several prominent venues. The most frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Cell Stem Cell
  • Nature Genetics
  • Cell Research

Recent selected papers demonstrate the scope of Hui's research:

  • Cell Plasticity in Liver Regeneration, 2020, Trends in Cell Biology
  • A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis, 2020, Cell Reports
  • Kupffer-cell-derived IL-6 is repurposed for hepatocyte dedifferentiation via activating progenitor genes from injury-specific enhancers, 2023, Cell Stem Cell
  • 25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages, 2024, Immunity
  • Progress in human liver organoids, 2020, Journal of Molecular Cell Biology

Hui frequently collaborates with several researchers, including:

  • Ludi Zhang
  • Zhen Sun
  • Baihua Wu
  • Lei Cui
  • Jin Cen

Best Publications

  • Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors

    Pengyu Huang;Zhiying He;Zhiying He;Shuyi Ji;Huawang Sun

  • Direct Reprogramming of Human Fibroblasts to Functional and Expandable Hepatocytes

    Pengyu Huang;Ludi Zhang;Yimeng Gao;Zhiying He

  • p38α suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway

    Lijian Hui;Latifa Bakiri;Andreas Mairhorfer;Norbert Schweifer

  • Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation

    Lijian Hui;Kurt Zatloukal;Harald Scheuch;Ewa Stepniak

  • YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial Homeostasis.

    Xin Zhou;Weiyun Li;Shuang Wang;Panli Zhang

  • Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38α in abrogating myoblast proliferation

    Eusebio Perdiguero;Vanessa Ruiz-Bonilla;Lionel Gresh;Lijian Hui

  • c-Jun/AP-1 controls liver regeneration by repressing p53/p21 and p38 MAPK activity

    Ewa Stepniak;Romeo Ricci;Robert Eferl;Grzegorz Sumara

  • Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin

    Lihua Min;Yuan Ji;Latifa Bakiri;Zhixin Qiu

  • MAPK signaling in inflammation-associated cancer development

    Pengyu Huang;Jiahuai Han;Lijian Hui

  • Expression profiling suggested a regulatory role of liver-enriched transcription factors in human hepatocellular carcinoma

    Liang Xu;Lijian Hui;Shaohui Wang;Jialei Gong

  • Chronic Liver Injury Induces Conversion of Biliary Epithelial Cells into Hepatocytes.

    Xing Deng;Xin Zhang;Weiping Li;Ren-Xin Feng

  • p38alpha: a suppressor of cell proliferation and tumorigenesis.

    Lijian Hui;Latifa Bakiri;Ewa Stepniak;Erwin F Wagner

  • High salt primes a specific activation state of macrophages, M(Na)

    Wu-Chang Zhang;Xiao-Jun Zheng;Lin-Juan Du;Jian-Yong Sun

  • Iron metabolism regulates p53 signaling through direct heme-p53 interaction and modulation of p53 localization, stability, and function.

    Jia Shen;Xiangpeng Sheng;Xiangpeng Sheng;ZeNan Chang;Qian Wu

  • Arid1a Has Context-Dependent Oncogenic and Tumor Suppressor Functions in Liver Cancer

    Xuxu Sun;Sam C. Wang;Yonglong Wei;Xin Luo

  • Mitogen-activated protein kinases in hepatocellular carcinoma development

    Lihua Min;Baokun He;Lijian Hui

  • In Vitro Expansion of Primary Human Hepatocytes with Efficient Liver Repopulation Capacity.

    Kun Zhang;Kun Zhang;Ludi Zhang;Wenming Liu;Xiaolong Ma

  • Reprogramming Fibroblasts into Bipotential Hepatic Stem Cells by Defined Factors

    Bing Yu;Zhi-Ying He;Pu You;Qing-Wang Han

  • Sequence variations in the mu-opioid receptor gene (OPRM1) associated with human addiction to heroin.

    Jinxiu Shi;Lijian Hui;Yonghai Xu;Feng Wang

  • The dominant hepatitis B virus genotype identified in Tibet is a C/D hybrid.

    Chaoyin Cui;Jinxiu Shi;Lijian Hui;Huifeng Xi

Frequent Co-Authors

Yixue Li
Yixue Li Chinese Academy of Sciences
Erwin F. Wagner
Erwin F. Wagner Medical University of Vienna
Hao Ying
Hao Ying Wayne State University
Mingyao Liu
Mingyao Liu University Health Network
Hans R. Schöler
Hans R. Schöler Max Planck Society
Luonan Chen
Luonan Chen Chinese Academy of Sciences
Yan Li
Yan Li Sun Yat-sen University
Bing Sun
Bing Sun Chinese Academy of Sciences
Wei Huang
Wei Huang Shanghai Jiao Tong University
Le Wang
Le Wang Pacific Northwest National Laboratory

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring a degree in Molecular Biology provides a solid foundation for many rewarding careers, but there are also several related fields you might consider. If you’re seeking flexibility or a different focus, online programs offer well-respected options suited to a range of needs and backgrounds.

Those interested in serving the community or military members may want to look into the best online colleges for military, which offer supportive resources tailored for service members and veterans. For individuals drawn to the human side of science, social work masters programs online can open doors to critical roles in health care, policy, and outreach.

If your interests intersect with psychology, consider pursuing one of the masters in psychology online for a pathway into research, clinical settings, or counseling. You can also deepen your expertise and qualify for licensure with an online masters degree in mental health counseling, which prepares graduates for meaningful work in mental health care.

Best Scientists Citing Lijian Hui

Trending Scientists

Recently Published Articles