World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
43
Citations
5266
World Ranking
4861
National Ranking
192

Overview

Joel A G van Roon is affiliated with the University Medical Center Utrecht in the Netherlands. Their research spans several fields of study, primarily within medicine and immunology and microbiology. The subfields of their work include physiology, immunology, surgery, rheumatology, and molecular biology.

Their research topics cover diverse aspects relevant to immunology and related medical disorders, with particular focus on:

  • Salivary gland disorders and functions
  • Salivary gland tumors diagnosis and treatment
  • Chemokine receptors and signaling
  • Immune response and inflammation
  • Immune cell function and interaction
  • Diabetes and associated disorders
  • Oral health pathology and treatment

Among their recent papers are:

  • "Leflunomide-hydroxychloroquine combination therapy in patients with primary Sjögren's syndrome (RepurpSS-I): a placebo-controlled, double-blinded, randomised clinical trial", 2020, The Lancet Rheumatology
  • "CXCL4 drives fibrosis by promoting several key cellular and molecular processes", 2022, Cell Reports
  • "Hyperresponsive cytosolic DNA-sensing pathway in monocytes from primary Sjögren's syndrome", 2022, Lara D. Veeken
  • "The Role of Interleukin-4 and Interleukin-10 in Osteoarthritic Joint Disease: A Systematic Narrative Review", 2022, Cartilage
  • "Implication of miR-126 and miR-139-5p in Plasmacytoid Dendritic Cell Dysregulation in Systemic Sclerosis", 2021, Journal of Clinical Medicine

They frequently publish in venues such as:

  • Frontiers in Immunology
  • Annals of the Rheumatic Diseases
  • The Lancet Rheumatology
  • Cell Reports
  • Lara D. Veeken

Collaboration is a notable aspect of their work. Frequent co-authors include:

  • Ana P. Lopes
  • Aike A. Kruize
  • Timothy R. D. J. Radstake
  • Helen L. Leavis
  • Aridaman Pandit

Best Publications

  • Single-Cell Analysis of Human Mononuclear Phagocytes Reveals Subset-Defining Markers and Identifies Circulating Inflammatory Dendritic Cells.

    Charles Antoine Dutertre;Charles Antoine Dutertre;Etienne Becht;Sergio Erdal Irac;Sergio Erdal Irac;Ahad Khalilnezhad;Ahad Khalilnezhad

  • Proinflammatory mediator–induced reversal of CD4+,CD25+ regulatory T cell–mediated suppression in rheumatoid arthritis

    Jocea M. R. van Amelsfort;Joel A. G. van Roon;Madelon Noordegraaf;Kim M. G. Jacobs

  • The Role of Ectopic Germinal Centers in the Immunopathology of Primary Sjögren's Syndrome: A Systematic Review

    Anna P. Risselada;Marjolein F. Looije;Aike A. Kruize;Johannes W.J. Bijlsma

  • Synergistic activity of interleukin-4 and interleukin-10 in suppression of inflammation and joint destruction in rheumatoid arthritis.

    Joel A. G. van Roon;Floris P. J. G. Lafeber;J. W. J. Bijlsma

  • The prognostic value of routinely performed minor salivary gland assessments in primary Sjögren's syndrome

    Anna P Risselada;Aike A Kruize;Roel Goldschmeding;Floris P J G Lafeber

  • Relationship between the type I interferon signature and the response to rituximab in rheumatoid arthritis patients

    Rogier M. Thurlings;Marie Boumans;Janneke Tekstra;Joel A. van Roon

  • The soluble leukocyte-associated Ig-like receptor (LAIR)-2 antagonizes the collagen/LAIR-1 inhibitory immune interaction.

    Robert Jan Lebbink;Maaike C. W. van den Berg;Talitha de Ruiter;Nicolas Raynal

  • Increased intraarticular interleukin‐7 in rheumatoid arthritis patients stimulates cell contact–dependent activation of CD4+ T cells and macrophages

    Joel A.G. Van Roon;Marieke C. Verweij;Marion Wenting Van Wijk;Kim M.G. Jacobs

  • Celecoxib: considerations regarding its potential disease-modifying properties in osteoarthritis

    Manon C Zweers;Tineke N de Boer;Joël van Roon;Johannes W J Bijlsma

  • Performance of a multi-biomarker score measuring rheumatoid arthritis disease activity in the CAMERA tight control study

    Marije F Bakker;Guy Cavet;Johannes Wg Jacobs;Johannes W J Bijlsma

  • Increased expression of interleukin-7 in labial salivary glands of patients with primary Sjögren's syndrome correlates with increased inflammation.

    A. Bikker;J. M. van Woerkom;A. A. Kruize;M. Wenting‐van Wijk

  • Brief report: enrichment of activated group 3 innate lymphoid cells in psoriatic arthritis synovial fluid.

    Emmerik F. A. Leijten;Tessa S. van Kempen;Marianne Boes;Jocea M. R. Michels-van Amelsfort

  • Blockade of the interleukin‐7 receptor inhibits collagen‐induced arthritis and is associated with reduction of T cell activity and proinflammatory mediators

    Sarita A. Y. Hartgring;Cynthia R. Willis;Dina Alcorn;Laurel J. Nelson

  • Elevated expression of interleukin-7 receptor in inflamed joints mediates interleukin-7-induced immune activation in rheumatoid arthritis.

    Sarita A. Y. Hartgring;Joel A. G. van Roon;Marion Wenting-van Wijk;Kim M. G. Jacobs

  • Interleukin 10 treatment of patients with rheumatoid arthritis enhances Fc gamma receptor expression on monocytes and responsiveness to immune complex stimulation.

    Joel A. G. Van Roon;Siska Wijngaarden;Floris P. J. G. Lafeber;Cora Damen

  • A shift in the balance of inhibitory and activating Fcgamma receptors on monocytes toward the inhibitory Fcgamma receptor IIb is associated with prevention of monocyte activation in rheumatoid arthritis.

    Siska Wijngaarden;Jan G. J. van de Winkel;Kim M. G. Jacobs;Johannes W. J. Bijlsma

  • Intra-articular CD1c-expressing myeloid dendritic cells from rheumatoid arthritis patients express a unique set of T cell-attracting chemokines and spontaneously induce Th1, Th17 and Th2 cell activity

    Frederique M Moret;Cornelis E Hack;Kim M G van der Wurff-Jacobs;Wilco de Jager

  • Interleukin-10 protects against blood-induced joint damage

    Nathalie W. D. Jansen;Goris Roosendaal;Michel J. J. Hooiveld;Johannes W. J. Bijlsma

  • Interleukin-7: a key mediator in T cell-driven autoimmunity, inflammation, and tissue destruction.

    Angela Bikker;C. Erik Hack;Floris P.J.G. Lafeber;Joel A.G. van Roon

  • Neutrophil extracellular trap release is associated with antinuclear antibodies in systemic lupus erythematosus and anti-phospholipid syndrome

    Maarten van der Linden;Lucas L van den Hoogen;Geertje H A Westerlaken;Ruth D E Fritsch-Stork;Ruth D E Fritsch-Stork

  • Serum microRNA screening and functional studies reveal miR-483-5p as a potential driver of fibrosis in systemic sclerosis.

    Eleni Chouri;Nila H. Servaas;Cornelis P.J. Bekker;Alsya J. Affandi

  • Heat-shock protein T-cell epitopes trigger a spreading regulatory control in a diversified arthritogenic T-cell response

    Willem van Eden;Ruurd van der Zee;Leonie S. Taams;A. Berent J. Prakken

  • IL4-10 Fusion Protein Is a Novel Drug to Treat Persistent Inflammatory Pain

    Niels Eijkelkamp;Cristine Steen-Louws;Sarita A Y Hartgring;Hanneke L D M Willemen

  • Leflunomide–hydroxychloroquine combination therapy in patients with primary Sjögren's syndrome (RepurpSS-I): a placebo-controlled, double-blinded, randomised clinical trial

    Eefje Hanna Martine van der Heijden;Sofie Liny Marie Blokland;Maarten Reinier Hillen;Ana Paula Pinheiro Lopes

  • Selective elimination of synovial inflammatory macrophages in rheumatoid arthritis by an Fcγ receptor I-directed immunotoxin

    Joel A. G. Van Roon;Anneke J. Van Vuuren;Siska Wijngaarden;Kim M. G. Jacobs

  • Mutual antagonism of rheumatoid arthritis and hay fever; a role for type 1/type 2 T cell balance

    Unknown

Frequent Co-Authors

Timothy R D J Radstake
Timothy R D J Radstake Utrecht University
Floris P. J. G. Lafeber
Floris P. J. G. Lafeber Utrecht University
Johannes W. J. Bijlsma
Johannes W. J. Bijlsma Utrecht University
Jan G. J. van de Winkel
Jan G. J. van de Winkel Genmab (United States)
Boudewijn M. T. Burgering
Boudewijn M. T. Burgering Utrecht University
Linde Meyaard
Linde Meyaard Utrecht University
Willem van Eden
Willem van Eden Utrecht University
Wilco de Jager
Wilco de Jager University Medical Center Utrecht
Marianne Boes
Marianne Boes Utrecht University
Peter J. Lenting
Peter J. Lenting University of Paris-Saclay

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Immunology in the USA opens doors to various interdisciplinary pathways, especially within healthcare and nursing. For professionals looking to advance, exploring fnp to acnp bridge program online options can be a practical route to specialize in acute care nursing, aligning well with immunology expertise.

Many students without a nursing background consider online absn programs for non nurses, which provide an accelerated pathway into nursing. These programs can complement immunology studies by offering foundational healthcare skills.

For those aiming to become nurse practitioners quickly, accelerated fnp programs offer an expedited path to family nurse practitioner roles, with potential integration of immunological knowledge for enhanced patient care.

Understanding earning potential is crucial in planning a career. Transparency on dnp salary transparency helps prospective students and practitioners gauge financial outcomes across different states before committing to advanced nursing degrees.

Best Scientists Citing Joel A G van Roon

Trending Scientists

Recently Published Articles