World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
66
Citations
20096
World Ranking
1606
National Ranking
813

Overview

Alberto Villanueva is affiliated with Memorial Sloan Kettering Cancer Center in the United States, focusing on research intersecting biochemistry, genetics, molecular biology, and medicine. Their work spans multiple subfields including molecular biology, oncology, cancer research, neurology, and pulmonary and respiratory medicine.

The scientist's research addresses several key topics, notably RNA modifications and cancer, neurofibromatosis and schwannoma cases, protein degradation and inhibitors, cancer genomics and diagnostics, cancer research and treatments, neuroblastoma research and treatments, and sarcoma diagnosis and treatment.

Villanueva has contributed to numerous publications across a variety of journals and venues. Frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory) with 13 publications, Nature Communications and Cancers with 4 each, Blood with 2, and Cell Death and Disease also with 2 publications.

Frequent co-authors in their work include August Vidal, María Martínez-Iniesta, Ramón Salazar, Manel Esteller, and Ernest Nadal.

Notable papers authored or co-authored by Villanueva include:

  • Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors, 2022, published in Nature Cancer
  • Epigenetic footprint enables molecular risk stratification of hepatoblastoma with clinical implications, 2020, published in Journal of Hepatology
  • Zonation of Ribosomal DNA Transcription Defines a Stem Cell Hierarchy in Colorectal Cancer, 2020, published in Cell Stem Cell
  • Multiple low dose therapy as an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours, 2020, published in Nature Communications
  • Tumors defective in homologous recombination rely on oxidative metabolism: relevance to treatments with PARP inhibitors, 2020, published in EMBO Molecular Medicine

Best Publications

  • Human polymorphism at microRNAs and microRNA target sites.

    Liuqing Yang;Chunru Lin;Chunyu Jin;Joy C. Yang

  • Patient-derived xenograft models: an emerging platform for translational cancer research.

    Manuel Hidalgo;Frederic Amant;Andrew V. Biankin;Eva Budinská

  • Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis.

    Sonia A. Melo;Hikaru Sugimoto;Hikaru Sugimoto;Joyce T. O’Connell;Noritoshi Kato

  • A microRNA DNA methylation signature for human cancer metastasis

    Amaia Lujambio;George A. Calin;Alberto Villanueva;Santiago Ropero

  • Interrogating open issues in cancer precision medicine with patient-derived xenografts

    Annette T. Byrne;Denis G. Alférez;Frédéric Amant;Daniela Annibali

  • Retraction: A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function

    Sonia A Melo;Santiago Ropero;Catia Moutinho;Lauri A Aaltonen

  • A DNA methylation fingerprint of 1628 human samples

    Augustin F. Fernandez;Yassen Assenov;Jose Ignacio Martin-Subero;Balazs Balint

  • Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer.

    Verónica Rodilla;Alberto Villanueva;Antonia Obrador-Hevia;Àlex Robert-Moreno

  • A Genetic Defect in Exportin-5 Traps Precursor MicroRNAs in the Nucleus of Cancer Cells

    Sonia A. Melo;Catia Moutinho;Santiago Ropero;George A. Calin

  • Basic Caenorhabditis elegans methods: synchronization and observation.

    Montserrat Porta-de-la-Riva;Laura Fontrodona;Alberto Villanueva;Julián Cerón

  • Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis

    V. Davalos;C. Moutinho;A. Villanueva;Raquel Boque

  • SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo.

    Sara Mainardi;Antonio Mulero-Sánchez;Anirudh Prahallad;Anirudh Prahallad;Giovanni Germano

  • Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing

    Sonia Melo;Alberto Villanueva;Catia Moutinho;Veronica Davalos

  • Disruption of the antiproliferative TGF-beta signaling pathways in human pancreatic cancer cells.

    A Villanueva;C García;A B Paules;M Vicente

  • Head-to-head antisense transcription and R-loop formation promotes transcriptional activation

    Raquel Boque-Sastre;Marta Soler;Cristina Oliveira-Mateos;Anna Portela

  • Intronic RNAs mediate EZH2 regulation of epigenetic targets

    Sònia Guil;Marta Soler;Anna Portela;Jordi Carrère

  • MAX inactivation in small cell lung cancer disrupts MYC-SWI/SNF programs and is synthetic lethal with BRG1.

    Octavio A. Romero;Manuel Torres-Diz;Eva Pros;Suvi Savola

  • Epigenetic inactivation of the circadian clock gene BMAL1 in hematologic malignancies.

    Hiroaki Taniguchi;Agustin F Fernández;Fernando Setién;Santiago Ropero

  • Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.

    Christopher A. Maxwell;Javier Benitez;Laia Gomez-Baldo;Ana Osorio

  • Tumor thymidylate synthase 1494del6 genotype as a prognostic factor in colorectal cancer patients receiving fluorouracil-based adjuvant treatment.

    Emma Dotor;Miriam Cuatrecases;María Martínez-Iniesta;Matilde Navarro

Frequent Co-Authors

August Vidal
August Vidal University of Barcelona
Manel Esteller
Manel Esteller Josep Carreras Leukaemia Research Institute
Gabriel Capellá
Gabriel Capellá Institut d'Investigació Biomédica de Bellvitge
Victor Moreno
Victor Moreno University of Barcelona
Holger Heyn
Holger Heyn Pompeu Fabra University
Josep M. Llovet
Josep M. Llovet University of Barcelona
Montse Sanchez-Cespedes
Montse Sanchez-Cespedes Instituto de Salud Carlos III
Conxi Lázaro
Conxi Lázaro Institut d'Investigació Biomédica de Bellvitge
Agustín F. Fernández
Agustín F. Fernández University of Oviedo
Enriqueta Felip
Enriqueta Felip Vall d'Hebron Institut de Recerca

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Related Online Degrees & Career Pathways

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Exploring these additional online degree options can deepen your knowledge and expand your future career pathways within science and healthcare.

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